Immunomagnetic Separation of B Type Acute Lymphoblastic Leukemia Cells from Bone Marrow With Flow Cytometry Validation and Microfluidic Chip Measurements
| dc.contributor.author | Icoz, Kutay | |
| dc.contributor.author | Eken, Ahmet | |
| dc.contributor.author | Cinar, Suzan | |
| dc.contributor.author | Murat, Aysegul | |
| dc.contributor.author | Ozcan, Servet | |
| dc.contributor.author | Unal, Ekrem | |
| dc.contributor.author | Deniz, Gunnur | |
| dc.date.accessioned | 2025-09-25T10:48:41Z | |
| dc.date.available | 2025-09-25T10:48:41Z | |
| dc.date.issued | 2021 | |
| dc.description | Deniz, Gunnur/0000-0002-0721-6213; Murat-Cifci, Aysegul/0000-0002-6823-4175; Eken, Ahmet/0000-0002-5816-0686; Icoz, Kutay/0000-0002-0947-6166; Ozcan, Servet/0000-0002-9914-8843; | en_US |
| dc.description.abstract | In order to detect the blast cells from bone marrow of patients, one strategy is to first isolate the cells using immunomagnetic beads. The aim of this study was to report the experimental results of the immunomagnetic separation efficiency of the blast cells from bone marrow of pediatric leukemia patients. To test the efficiency of immunomagnetic separation, flow cytometry measurements at critical steps were performed. We here reported 94.5% capture efficiency for CD10 nano beads. Patients samples were also analyzed with a microfluidic chip to test the feasibility for further developments. | en_US |
| dc.description.sponsorship | Turkiye Bilimsel ve Teknolojik Arastirma Kurumu [115E020] | en_US |
| dc.description.sponsorship | This work was supported by the Turkiye Bilimsel ve Teknolojik Arastirma Kurumu [project number: 115E020]. | en_US |
| dc.identifier.doi | 10.1080/01496395.2020.1835983 | |
| dc.identifier.issn | 0149-6395 | |
| dc.identifier.issn | 1520-5754 | |
| dc.identifier.scopus | 2-s2.0-85093978240 | |
| dc.identifier.uri | https://doi.org/10.1080/01496395.2020.1835983 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.12573/3975 | |
| dc.language.iso | en | en_US |
| dc.publisher | Taylor & Francis inc | en_US |
| dc.relation.ispartof | Separation Science and Technology | en_US |
| dc.rights | info:eu-repo/semantics/closedAccess | en_US |
| dc.subject | B Type Acute Lymphoblastic Leukemia | en_US |
| dc.subject | Immunomagnetic Separation | en_US |
| dc.subject | Flow Cytometry | en_US |
| dc.subject | Bone Marrow | en_US |
| dc.subject | Hematogone | en_US |
| dc.subject | Microfluidic Chip | en_US |
| dc.title | Immunomagnetic Separation of B Type Acute Lymphoblastic Leukemia Cells from Bone Marrow With Flow Cytometry Validation and Microfluidic Chip Measurements | en_US |
| dc.type | Article | en_US |
| dspace.entity.type | Publication | |
| gdc.author.id | Deniz, Gunnur/0000-0002-0721-6213 | |
| gdc.author.id | Murat-Cifci, Aysegul/0000-0002-6823-4175 | |
| gdc.author.id | Eken, Ahmet/0000-0002-5816-0686 | |
| gdc.author.id | Icoz, Kutay/0000-0002-0947-6166 | |
| gdc.author.id | Ozcan, Servet/0000-0002-9914-8843 | |
| gdc.author.scopusid | 24801985000 | |
| gdc.author.scopusid | 36476996200 | |
| gdc.author.scopusid | 8686750300 | |
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| gdc.author.scopusid | 26644286400 | |
| gdc.author.scopusid | 15058356700 | |
| gdc.author.scopusid | 15058356700 | |
| gdc.author.wosid | Icoz, Kutay/Abi-3903-2020 | |
| gdc.author.wosid | , Gunnur Deniz/Aac-2909-2020 | |
| gdc.author.wosid | Eken, Ahmet/Aak-4232-2021 | |
| gdc.author.wosid | Icoz, Kutay/J-2063-2015 | |
| gdc.author.wosid | Unal, Ekrem/A-5099-2019 | |
| gdc.author.wosid | Cinar, Suzan/J-4770-2019 | |
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| gdc.bip.influenceclass | C5 | |
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| gdc.coar.access | metadata only access | |
| gdc.coar.type | text::journal::journal article | |
| gdc.collaboration.industrial | false | |
| gdc.description.department | Abdullah Gül University | en_US |
| gdc.description.departmenttemp | [Icoz, Kutay] Abdullah Gul Univ, BioMINDS Bio Micro Nano Devices & Sensors Lab, Dept Elect & Elect Engn, Kayseri, Turkey; [Icoz, Kutay] Abdullah Gul Univ, Bioengn Dept, Kayseri, Turkey; [Eken, Ahmet; Murat, Aysegul; Ozcan, Servet; Unal, Ekrem] Erciyes Univ, Genome & Stem Cell Ctr GENKOK, Kayseri, Turkey; [Cinar, Suzan; Deniz, Gunnur] Istanbul Univ, Aziz Sancar Inst Expt Med, Dept Immunol, Istanbul, Turkey; [Ozcan, Servet] Erciyes Univ, Biol Dept, Kayseri, Turkey; [Unal, Ekrem] Erciyes Univ, Pediat Hematol & Oncol Dept, Kayseri, Turkey | en_US |
| gdc.description.endpage | 2666 | en_US |
| gdc.description.issue | 15 | en_US |
| gdc.description.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
| gdc.description.scopusquality | Q3 | |
| gdc.description.startpage | 2659 | en_US |
| gdc.description.volume | 56 | en_US |
| gdc.description.woscitationindex | Science Citation Index Expanded | |
| gdc.description.wosquality | Q3 | |
| gdc.identifier.openalex | W3094381058 | |
| gdc.identifier.wos | WOS:000581167200001 | |
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| gdc.oaire.keywords | bone marrow | |
| gdc.oaire.keywords | flow cytometry | |
| gdc.oaire.keywords | B type acute lymphoblastic leukemia | |
| gdc.oaire.keywords | hematogone | |
| gdc.oaire.keywords | microfluidic chip | |
| gdc.oaire.keywords | immunomagnetic separation | |
| gdc.oaire.popularity | 8.041266E-9 | |
| gdc.oaire.publicfunded | false | |
| gdc.oaire.sciencefields | 0301 basic medicine | |
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| gdc.virtual.author | İçöz, Kutay | |
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