Scopus İndeksli Yayınlar Koleksiyonu

Permanent URI for this collectionhttps://hdl.handle.net/20.500.12573/395

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Does Your Love Lift Me Higher? A Direct Replication of the Energising Role of Secure Relationships
(John Wiley and Sons Inc, 2026) Lağap, A.C.; Harma, M.
Previous work has revealed that priming people with significant others increases feelings of security and energy, and in turn, boosts exploration motivations. In this preregistered study, we directly replicated Luke et al.'s (2012) Study 2 (N = 281). We found similar results as the replicated study regarding increased security feelings and exploration motivations on the self-report measures after the priming. However, we did not find any support for the increased energy feelings after the attachment security priming. In addition, contrary to Luke et al.'s (2012) results, energy feelings did not mediate the relationship between security priming and exploration motivations. A discussion of null findings, along with the limitations of self-reports and potential misinterpretation of the mediational analyses, follows. We also discuss possible future implications of the current findings. © 2025 International Union of Psychological Science.
Measuring Disaster Resilience in MENA Countries and Its Impact on Disaster Losses
(Nature Research, 2025) Demir, A.; Dinçer, A.E.; Dincer, N.N.
Disaster resilience is a protective feature aimed at reducing the effects of natural disaster events and losses resulting from these events. This study develops a Disaster Resilience Index (DRI) for MENA countries to assess resilience across ten dimensions, including economic, social, institutional, infrastructural, and environmental factors. Unlike most prior studies, which focus on individual countries or use narrower sets of indicators, this study provides a multi-country, region-specific framework tailored to MENA’s socio-economic and environmental heterogeneity. The index integrates geospatial data on disaster risk from geographic information systems (GIS) and a natural hazard risk dimension. Validation using disaster-related fatalities, supported by a dual PCA-based sensitivity analysis, confirms the robustness of the DRI and reveals that countries with stronger governance, higher human capital, and robust infrastructure tend to exhibit greater resilience, while fragile states and resource-dependent economies are more vulnerable. Notably, the DRI calculated using both dimension-specific and all-indicator PCA produces closely aligned values, indicating the choice of conducting PCA at the dimension level does not significantly alter the overall assessment of disaster resilience. These insights provide a foundation for targeted disaster risk reduction strategies and highlight areas where international cooperation and policy interventions can strengthen resilience in the region. © The Author(s) 2025.
Clean Energy Production and Decarbonization of Energy Sector With Floating Photovoltaic Systems
(Institute of Physics, 2025) Bajc, T.; Ozgun, F.; Koca, K.; Karipoğlu, F.
Floating photovoltaic systems (FPVS) offer several advantages over traditional land-based PV systems, which has contributed to a growing global interest in their deployment. Since the energy yields are strongly dependent on location and tilt angle of FPVS, this research focuses on the clean energy production and decarbonization potential of FPVS in Serbia and Türkiye for different water bodies, such are natural and artificial lakes and dams. The research is performed for the most appropriate lakes and dams, having in mind importance of the location, energy yields potential, distance from the electricity grid and main roads, environmental impact, water depth and land type quality. Tilt angles are analyzed in a range from 5 to 40°, and the optimal angle is depicted for selected locations. The highest energy yields for Türkiye were obtained for 30° tilt angle, while for Serbia it was 36°. The results showed that possible clean energy production in both countries reaches 15345 kWh of energy in total, while the yearly carbon emissions reduction for all selected locations goes up to 10.76 tCO2/year in total. Since the legal framework for the application of FPVS is not established yet in observed countries, these results contribute to the future development of legislation in the field of FPVS and encourage the stakeholders to invest in clean energy production. © Published under licence by IOP Publishing Ltd.
Offshore Floating Modular Energy Islands: Technologies and Challenges
(Institute of Physics, 2025) Gkantou, M.; Amlashi, H.; Snæbjörnsson, J.; Skejic, D.; Ferri, G.; Marino, E.; Baniotopoulos, C.
Offshore floating modular energy islands (FMEIs) represent a promising solution to meet growing global energy demands, while addressing challenges associated with conventional energy infrastructure. This paper explores key technological components underpinning the design, construction, and energy generation of FMEIs, with a focus on three core areas: energy generation systems, floating structures and construction methods. The first technological component focuses on energy generation systems, examining the technologies of offshore wind power, solar and wave energy, to maximise overall energy production, while also highlighting the challenges involved in integrating these technologies. The second section examines the support structure of offshore floating platforms, as well as the key role of mooring systems in ensuring structural integrity under challenging marine conditions. The importance of advanced monitoring and maintenance strategies for long-term viability is also discussed. The third technological component discusses modular construction, highlighting the material choices and associated construction challenges in building FMEIs. This review also includes case studies and ongoing projects that demonstrate the real-world application of these technologies. Through the integration of advanced renewable energy generation technologies, floating and mooring systems and modular construction methods, FMEIs offer a sustainable and innovative approach to offshore energy production. This paper provides an overview of FMEIs and contributes to advancing development in this emerging field. © Published under licence by IOP Publishing Ltd.
Modular Floating Energy Islands With Green Hydrogen Integration: Design of a Small-Scale P2x Scheme
(Institute of Physics, 2025) Akpolat, A.N.; Cundeva, S.; Todorovic, J.; Rexhepi, V.; Okhay, O.; Bakon, T.; Borg, R.P.
The climate crisis and rising carbon emissions make the integration of renewable energy systems into electricity grids worldwide inevitable. In this context, modular floating energy islands (MFEI) provide innovative solutions for hybrid systems with high renewable energy penetration. This study explores the simultaneous use of various renewable resources, such as solar, wind, tidal, and wave energy, through small-scale MFEI structures that can be situated in seas and lakes. Thanks to their modular design, these systems offer benefits like scalability, portability, and ease of maintenance, allowing for flexible and adaptive developments in the energy infrastructure. As highlighted in recent literature (e.g., the North Sea Wind Power Hub and EU H2Ocean projects), offshore structures for green hydrogen production support energy storage and carbon-free fuel conversion within the Power-to-X (P2X) framework. This study evaluates the potential of photovoltaic (PV)-supported hydrogen production in MFEI structures through numerical analyses. The results emphasize the strategic role of these structures in enhancing energy security, coastal protection, and reducing carbon emissions by producing significant amounts of hydrogen. This hydrogen can be used for various purposes, including re-electrification, industrial applications, heating, and agriculture. Future research should focus on real-time data optimization, AI-supported system management, and integrated hydrogen consumption scenarios. © Published under licence by IOP Publishing Ltd.
Design and Analysis of a Solar-Assisted Combined Cooling, Heating, and Power System for Smart Cities: Case Study From Doha
(IGI Global, 2025) Akroot, A.; Almohammedi, A.A.; Talal, W.
The rising demand for sustainable and energy-efficient solutions in urban areas has driven interest in renewable systems for smart cities. This chapter presents a solar-assisted combined cooling, heating, and power (SA-CCHP) system designed for Doha, Qatar, where high solar radiation and cooling needs prevail. Powered solely by a parabolic trough collector (PTC) field, the system delivers net power from 1200 kW in winter to 195 kW in summer, with cooling loads of ~2100-3400 kW and heating loads of ~90)00-14500 kW. Increasing the superheating degree at the ORC turbine inlet enhances power and heating but reduces cooling, while raising the pressure ratio (A) from 0.5 to 0.8 boosts net output and efficiency, cutting CO2 emissions from 0.22 to 0.13 kg/kWh. Overall energy efficiency rises from 85% to 90% and exergy efficiency from 76% to 78.5%, while costs decline from $40/hr to $36/hr, confirming both environmental and economic viability. The study demonstrates the feasibility of solar-powered CCHP systems as scalable models for achieving clean energy goals in smart cities. © 2026, IGI Global Scientific Publishing. All rights reserved.
Fully Flexible, Low-Cost, Environmentally Friendly Yarn-Based Inp/Ag Nw Photodetectors for UV-Visible Light Detection
(SPIE, 2025) Savaş, M.; Akrema, A.; Ocal, S.K.; Erdem, T.
We report the fabrication and investigate of a novel photodetector using a heterostructure of InP quantum dots (QDs) and silver nanowires (Ag NWs) incorporated into yarn. This device is simple, scalable, low-cost, flexible, and functions under ambient conditions. Ag NWs and red-emitting InP QDs were separately synthesized via chemical methods and mixed in a specific ratio to coat functional yarns, which were then knitted into fabrics. The photodetector benefits from the excellent electrical conductivity of Ag NWs and the strong optical absorption of InP QDs. It shows enhanced photoelectric response in both UV and visible regions. At 405 nm illumination, the device achieves a photoresponsivity of 5.8 mA W-1 and a detectivity of 2 × 1010 Jones-values comparable to or exceeding those of similar devices. The enhanced performance is attributed to efficient charge transfer enabled by favorable band alignment between Ag NWs and InP QDs, along with synergistic effects from nanostructure dimensionality and quantum confinement. The device's combination of flexibility, sensitivity, and cost-efficiency makes it a strong candidate for wearable UV-visible photodetectors. © 2025 SPIE. All rights reserved.
Minimising the Cycle Time with Assembly Line Balancing and Worker Assignment: A Case Study in a Medical Device Manufacturer Company
(ISRES Publishing, 2025) Kayser, A.; Sipahi, G.; Sevimli, O.; Toplu, N.; Turan, S.; Satic, U.
In this research, we considered the mixed-model assembly line balancing and worker assignment problems of a medical device manufacturer in Türkiye. We combined these problems into a single integer programming model where multiple types of products can be assembled simultaneously on a single assembly line, and workers are assigned to workstations based on their abilities while ensuring the balance and efficiency of the assembly line. Our proposed approach seeks to minimise the cycle time and ability-based assignment costs on the assembly line. We used the Gurobi solver to find the optimal solution for the proposed problem. Our approach provides higher efficiency and results in a 76% increase in productivity without requiring additional work hours or workers. © 2025 Published by ISRES Publishing.
Scheduling in Flexible Flow Shop Environments with Re-Entrant Jobs and Heterogeneous Workers
(ISRES Publishing, 2025) Bekli, S.; Kayisoglu, B.
In many industries, manufacturing is organized as a flexible flow shop (FFS), which has gotten the researchers' attention. The scheduling studies, particularly those on FFS scheduling, are concerned with homogeneous workers with the same skill set or heterogeneous workers who can only perform one specific type of operation on the production lines. Moreover, jobs are mainly assumed to go through an operation once. Yet, in real-life production, workers might have different skill sets with varying processing times. Furthermore, certain jobs may require revisiting the same machine multiple times, i.e., re-entrant jobs. We study an FFS environment with re-entrant jobs, considering worker flexibility. We propose a mixed integer linear programming model to find the optimal sequences of jobs to be processed by the multiskilled workers assigned to the production system, ensuring each re-entrant job waits for a predefined time window before reprocessing on the same operation. The objective of the model is to minimize makespan. We tested the proposed model on a dataset taken from a real production system of a PVC windows and doors production facility. © 2025 Published by ISRES Publishing.
Ultra-Durable Information-Encoded Anti-Counterfeiting Self-Assembled Nanocrystal Labels
(Wiley-VCH Verlag GmbH, 2025) Haddadifam, Taha; Shabani, Farzan; Kalay, Mustafa; Khaligh, Aisan; Mutlugun, Evren; Onses, Mustafa Serdar; Demir, Hilmi Volkan
Forgery, a serious universal problem, is causing huge economic losses every year. Against forgery, information-encoded labelling systems have attracted significant attention for a diverse range of anti-counterfeiting applications. Here, cost-effective and ultra-durable nanocrystal-based labels are proposed and demonstrated in which information can be encoded as physically unclonable functions (PUFs) of hardware-oriented security systems. The fabrication method of the PUFs is based on the self-assembly of colloidal quantum wells (CQWs) and generation of unclonable features within their pattern at a liquid-liquid interface. These CQW PUFs are analyzed with well-known statistical tests, which show a uniqueness level of 0.5060 +/- 0.0323 and prove their randomness. In addition, a feature-matching algorithm is used to authenticate these information-encoded CQW PUFs. For the safety of the semiconductor chips, a CQW PUF is attached to the surface of the chip to protect against hardware cyber-attacks. Eventually, fabricated labels are examined against high temperatures and moisture environments. The fabricated CQW label is durable for a period of 150 days it is tested, demonstrating ultra-high stability of the label. High stability and durability, cost-effectiveness, and high encoding capacity make these proposed nanocrystal labels extremely attractive for large-scale commercialization.
Neuroinflammatory Human Brain Organoids Enable Comprehensive Drug Screening Studies: Fingolimod and Its Analogues in Focus
(Bentham Science Publishing Ltd, 2026) Acar, Busra; Pepe, Nihan Aktas; Zivkovic, Aleksandra; Stark, Holger; Sen, Alaattin
Introduction The absence of physiologically relevant models for neuroinflammatory brain disorders, such as multiple sclerosis (MS), highlights the need for improved drug screening platforms. To bridge this gap, this study aimed to develop a human brain organoid (hBO) model incorporating essential neural cell types, including astrocytes, microglia, and oligodendrocytes.Methods hBOs were generated from H9 stem cells, and neuroinflammatory characteristics were elicited by lipopolysaccharide (LPS). The expression of specific neuronal and inflammatory markers was assessed through qRT-PCR, immunofluorescence staining (IFS), and ELISA.Results IFS of mature hBOs with anti-SOX2, anti-SATB2, anti-MAPT, anti-GFAP, anti-MBP, and anti-IBA1 antibodies and images collected with the confocal microscope confirmed the differentiation of H9 cells into cortical neurons, astrocytes, microglia, and oligodendrocyte cell types. Elevated GFAP, IBA1, NF-kappa B, and IL-6 levels, along with reduced CNPase expression with LPS treatment, were considered reflective of MS-like pathology and were used to test fingolimod and its derivatives. Fingolimod and all its derivatives, specifically ST-1505, decreased MAPT (2.1-fold in ELISA, 1.7-fold in IFS), GFAP (1.8-fold in IFS), TNF alpha (5.4-fold in qRT-PCR), and FABP (1.5-fold in ELISA) levels, and increased IL-10 (11-fold in qRT-PCR) and MBP (2.9-fold in IFS) levels.Discussion The present data collectively showed LPS to evoke neuroinflammation in the hBO model, while fingolimod and its derivatives, particularly ST-1505, exhibited significant anti-inflammatory and neuroprotective properties by counteracting these evoked changes in the hBO model.Conclusion The findings supported the applicability of brain organoids as a model system for drug screening studies for neuroinflammatory brain diseases.
Toward the Design of New Α-Carboline Derivatives Against Anaplastic Lymphoma Kinase (Alk): A Comprehensive in Silico Approach
(Wiley-VCH Verlag GmbH, 2025) Sari, Ceyhun; Akcok, Ismail
After the first description of anaplastic lymphoma kinase (ALK) in an anaplastic large cell lymphoma cell line as a nucleophosmin (NPM) fusion partner, ALK and its various fusion partners have been implicated in numerous cancers such as non-small cell lung cancer (NSCLC), anaplastic large cell lymphoma (ALCL), neuroblastoma, and rhabdomyosarcoma. In the last decade, several compounds targeting ALK have been developed and approved by the Food and Drug Administration (FDA). Despite the advances of generations of ALK inhibitors, a recent study highlighted that around half of the ALK-positive NSCLC patients will go through disease progression in response to first-line alectinib, which is a second-generation ALK inhibitor. In this study, we aimed to propose a novel alpha-carboline compound targeting the ALK tyrosine kinase domain to be used against various types of cancer in which ALK fusion proteins may be involved. In this regard, we designed more than 200 alpha-carboline derivatives and investigated their binding properties against ALK tyrosine kinase by using in silico protocols consisting of molecular docking studies, molecular dynamics simulations, MM/PBSA binding free energy calculation, and essential dynamics analysis. Considering the obtained results, we developed two promising candidates, compounds 208 & 209 with -9.05 and -9.80 binding energies, respectively, which demonstrated improved binding profiles over the course of a 300 ns simulation.
Crashworthiness Evaluation of 3D-Printed Hybrid-Design Multi-Cell Energy Absorbers Under Lateral Compression for Unmanned Aerial Vehicles
(Springer Heidelberg, 2025) Atahan, M. Gokhan; Zeybek, Halil; Ozturk, Sezgin
Energy absorbers can be strategically integrated into critical areas of unmanned aerial vehicles to protect their structural integrity and electronic components in the event of an accident. In this study, hybrid-design multi-cell energy absorber configurations were proposed, and their crashworthiness performance and collapse mechanisms were comparatively analyzed. Hybrid energy absorbers were designed considering circular, square, hexagonal, and re-entrant unit cell geometries. The energy absorber configurations were produced via additive manufacturing. Compared to the single-cell circular energy absorber, the hybrid-design multi-cell approach resulted in a higher peak crushing force value, while offering considerable enhancements in other crashworthiness parameters. Configuration 3 is recommended for use in energy absorber applications in unmanned aerial vehicles due to its superior crashworthiness performance. Moreover, in hybrid-design multi-cell energy absorbers, the selection of layer geometries significantly influences deformation capability. Compared to the single-cell circular configuration (Configuration 1), Configuration 3 demonstrated superior crashworthiness performance by increasing the MCF, EA, and SEA values by 7.47, 4.47, and 1.41 times, respectively.
Tuning Properties of Amorphous Boron Via Hydrogenation: An Ab Initio Study
(Elsevier, 2026) Durandurdu, Murat
Ab initio simulations are employed to investigate the structural, mechanical, and electronic properties of hydrogenated amorphous boron (a-B:H) across a range of hydrogen concentrations (approximate to 6-21 at.%). The results indicate that pentagonal-like boron clusters constitute the primary structural motifs. The bonding environment consists of both B-H terminal bonds and B-H-B bridging bonds, with the fraction of bridging bonds ranging from 10 % to 16 %. Increasing the hydrogen content leads to a reduction in density and bulk modulus, accompanied by a systematic widening of the electronic band gap. These results demonstrate that hydrogen incorporation profoundly modifies the atomic structure, softens the network, and enhances the semiconducting character of a-B:H, highlighting the tunability of properties in boron-based amorphous materials.
A Potential Hemostatic Chitosan/Gelatin Cryogel Impregnated with Verbascum Thapsus Leaf Extract for Noncompressible Hemorrhage Management
(IOP Publishing Ltd, 2025) Uzuner, Hacernur; Yuruk, Adile; Isoglu, Ismail Alper
In this study, we prepared a series of chitosan/gelatin (CS/GEL) cryogels containing Verbascum thapsus (V. thapsus) leaf extract and identified a lead formulation for noncompressible hemorrhage (NCH). Cryogels with average pore diameters ranging from 225 to 478 mu m were fabricated through cryogelation at various CS/GEL ratios. C15 was chosen as the base scaffold due to its homogeneous pore distribution, with a pore size coefficient of variation (CV) of approximately 0.22. Extract loading was 1%, 5%, 10%, and 20% w/v. Functional porosity was reported by the relative accessible void index (RAVI). In PBS, the values relative to neat C15 were 1.00, 0.27, 0.20, 0.13, and 0.09 for concentrations of 0%, 1%, 5%, 10%, and 20% w/v, respectively. In citrated blood, the series was 1.00, 0.29, 0.12, 0.14, and 0.09. After loading, equilibrium swelling decreased and the compressive modulus increased, consistent with partial pore filling in a fixed network. The cryogels maintained an interconnected macroporous network and showed swelling from 300% to 3600% in blood and PBS. Antibacterial activity reached 89% inhibition, and cell viability remained above 80%. Hemolysis was low and within acceptance limits. Clotting improved in whole blood as the blood clotting index decreased from 11.9 to 6.5, and the clotting time was approximately 6 min. The 5% w/v group provided the optimal balance of clotting, antibacterial effects, and biocompatibility. This study presents a novel hemostatic CS/GEL cryogel containing V. thapsus leaf extract that holds strong potential for future applications in NCH management.
Boundaries of Belonging: the Spatial and Social Logic of Being Yilli People in Kayseri
(Sage Publications Inc, 2025) Mus Ozmen, Nihan; Asiliskender, Burak; Ozmen, Zehni
This study explores the spatial, social, and cultural dynamics of being yilli, a deeply rooted local identity in Kayseri, Turkey. Drawing on ethnographic fieldwork, oral histories, and spatial analysis, it examines how the yilli people negotiate urban transformation through selective adaptations to modernization while maintaining traditional social boundaries. The research shows that the yilli do not passively resist change but actively reinterpret modernization to reinforce status, kinship, and symbolic belonging. Spatial relocation and investment patterns reflect economic strategies and efforts to preserve cultural distinction amid urban expansion. The findings demonstrate that urban transformation in Kayseri is both a material and cultural process, shaped by layered histories of memory, hierarchy, and social imagination. Through the case of the yilli, the study contributes to broader debates in urban sociology and cultural geography, offering insights into how culture-centered societies adapt to and reshape modernization processes.
Engineering a Bilayered Scaffold as a Potential Cardiac Patch: From Scaffold Design to in Vitro Assessment
(Springer Singapore Pte Ltd, 2025) Yuruk, Adile; Duzler, Ayhan; Isoglu, Sevil Dincer; Isoglu, Ismail Alper
In this study, we developed a novel bilayered scaffold consisting of a bottom layer composed of the Decellularized Bovine Pericardium (DP) coated with Polyaniline Nanoparticles (PANINPs) and a top layer made of an electrospun Poly(lactic-co-glycolic acid)/Gelatin (PLGA/Gel) membrane incorporated with Vascular Endothelial Growth Factor (VEGF) and hawthorn extract. Functionally, the DP supplies native Extracellular Matrix (ECM) components and mechanical support, while PANINPs provide conductivity. The electrospun PLGA/Gel layer mimics fibrous ECM. It incorporates bioactives, with VEGF promoting pro-angiogenic stimulation and hawthorn extract enhancing anticoagulant activity, as well as increasing surface hydrophilicity. The tissue adhesive ensures the interfacial integrity between the two layers. Decellularization efficiency was confirmed histologically using 4 ',6-diamidino-2-phenylindole (DAPI) and Hematoxylin-Eosin (H&E) staining. The DP exhibited a DNA content of 115.9 +/- 47.8 ng/mg DNA, compared to 982.88 +/- 395.42 ng/mg in Native Pericardium (NP). The PANINPs had an average particle size of 104.94 +/- 13.7 nm. The conductivity of PANINPs-coated decellularized pericardium was measured to be 9.093 +/- 8.6 x 10- 4 S/cm using the four-point probe method. PLGA/Gel membranes containing hawthorn extract (1%, 5%, 10%, and 15% w/v) and VEGF (0.1 mu g/mL, 0.5 mu g/mL, and 1 mu g/mL) were fabricated by electrospinning, resulting in fiber diameters between 850 and 1200 nm and pore sizes between 14 and 20 mu m. The anticoagulant efficiency of the membranes containing hawthorn extract reached 430 s in the Activated Partial Thromboplastin Time Assay (aPTT). Mechanical testing revealed a tensile strength of 22.70 +/- 6.33 MPa, an elongation of 53.58 +/- 10.63%, and Young's modulus of 0.67 +/- 0.10 MPa. The scaffold also exhibited over 91% cell viability and excellent cardiomyocyte adhesion. The hemolysis ratio was determined to be 0.421 +/- 0.191%, which confirms its blood compatibility. Our results indicate that the proposed bilayered scaffold can be a promising candidate for cardiac patch applications.
Numerical Analysis and Experimental Comparison of Stress and Stiffness Parameters of Steel Reinforced Geopolymer Concrete Columns
(Elsevier Sci Ltd, 2026) Ozbayrak, Ahmet; Kucukgoncu, Hurmet; Aslanbay, Huseyin Hilmi; Aslanbay, Yuksel Gul; Altun, Fatih
Despite extensive research, Geopolymer concrete (GPC) lacks reinforced concrete construction and design specifications. Developing such specifications requires comprehensive studies to promote the use of GPC, which is known for its superior performance and environmental benefits compared to ordinary Portland cement concrete (OPC). This study numerically investigated and compared the behavior and strength of fly ash-based geopolymer-reinforced concrete columns with the experimental results. Comparisons with OPC were made based on existing specifications. Herein, FEM analyses were conducted on 16 GPC and 4 OPC columns under eccentric axial compressive loads. Parameters such as eccentricity, reinforcement ratio, curing method, and activation solution ratios were varied. According to average numerical results, the GPC columns have 7% more moment capacity and 30% more curvature values than OPC. Moreover, GPC columns absorbed more energy than OPC columns. Also, GPC columns have higher axial load and bending moment carrying capacities than OPC for numerical results. Error analysis between FEM and experimental data revealed a strong correlation, with MAPE values of 8.88% (axial load) and 7.20% (moment) for GPC columns, confirming the reliability of the numerical model. ACI 318 and Eurocode 2 specifications were deemed applicable for GPC columns, provided axial loads are limited per TEC 2018.
Vim-Polyp: Multimodal Colon Polyp Dataset with Video, Histopathology, and Protein Expression
(Nature Portfolio, 2025) Dogan, Refika Sultan; Akay, Ebru; Dogan, Serkan; Yilmaz, Bulent
The dataset in this study includes 202 videos with a total of 422 minutes, reaching Kayseri City Hospital's gastroenterology department as colonoscopy videos and 1903 microscopy images between 2019 and 2021. It includes 399 colonoscopy, microscopy images, and pathological diagnoses of polyps, as well as immunohistochemical staining results for proteins that play an important role in the assessment of cancerous cells, such as staining results for p53 (clone: bp53-11), Ki-67 (clone: 30-9), CD34 (clone: QBend/10), PD-L1 (clone: SP142), BRAF (clone: V600E) and VEGF (clone: SP125). By sharing the data openly, we aim to facilitate benchmarking, exploratory analysis and transfer-learning studies on colorectal polyps and cancer. In combination with external datasets or pretrained models, the resource can help advance data-driven detection and characterisation work. The diverse range of polyps assigned to cancer stages from 201 patients makes this tool valuable for researchers and clinicians in furthering diagnosis and treatment.
Development and Characterization of Starch-Fatty Acid Complexes Produced with Buckwheat Starch and Capric/Stearic Acid Using Different Reaction Conditions
(Elsevier, 2025) Oskaybas-Emlek, Betul; Ozbey, Ayse; Aydemir, Levent Yurdaer; Kahraman, Kevser
The aim of present study was to investigate the impact of reaction parameters on the complex formation between buckwheat starch and capric acid (B-Capric) or stearic acid (B-Stearic). The most effective parameters on complex formation indicator (Complex index (CI) value) were found as reaction temperature (60-90 degrees C) and pH (5-8). Additionally, the effect of these parameters on physicochemical, pasting, and in-vitro digestibility properties of complex samples were evaluated. XRD and FTIR was also used in characterize the complex samples. In general, increasing pH increased the CI values of B-Stearic samples while decreasing those of B-Capric samples. Syneresis of buckwheat starch increased after complexation while paste clarity and swelling power diminished. The pasting properties of native starch significantly changed after complex formation. The FTIR results showed that starch structure changed with complex formation. XRD revealed that buckwheat starch, having an A-type pattern, converted to V-type pattern after complexation. Complex formation of buckwheat starch with capric and stearic acid significantly increased the RS content of buckwheat starch (19.01 %) by up to 36.25 % and 30.60 %, respectively. These results highlight the possibility of using buckwheat starch-capric acid/stearic acid complexes in food formulation to enhance the RS content.

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