Scopus İndeksli Yayınlar Koleksiyonu

Permanent URI for this collectionhttps://hdl.handle.net/20.500.12573/395

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  • Article
    Citation - WoS: 5
    Citation - Scopus: 7
    Rational Design of EDTA-Incorporated Nanoflowers as Novel and Effective Endodontic Disinfection Against Biofilms
    (Springer, 2023-10-03) Aslan, Tugrul; Dadi, Seyma; Kafdag, Ozgur; Temur, Nimet; Ildiz, Nilay; Ocsoy, Ismail; Ustun, Yakup
    The ethylenediaminetetradiacetic acid (EDTA) is one of the most commonly used irrigation solutions. Although EDTA has a very low antimicrobial property, it is used to remove inorganic part of smear layer in areas of root canal system. Herein, we developed EDTA-incorporated nanoflowers (EDTA NFs), for the first time, as novel and effective irrigation solution with quite high antimicrobial property to provide complete disinfection in root canal system. We both systematically elucidated the formation of the EDTA NFs with various techniques, and their catalytic and antimicrobial activities in the presence of hydrogen peroxide (H2O2) were documented through intrinsic EDTA property and peroxidase-like activities.
  • Book Part
    Citation - Scopus: 1
    Green Magnetic Nanoparticles in Enzyme Immobilization
    (Elsevier, 2024) Dadi, Seyma; Alrifai, Wardishan Kassem; Öçsoy, Ismail
    Enzymes as highly efficient biocatalysts are widely used in various biotechnological sectors including cosmetic, textile, food, and detergent. However, their practical applications can be hampered due to high expense and challenges in the extraction, separation, and purification steps. Additionally, enzymes have limited activity and stability at high temperature and different pH values. Aiming to overcome these challenges, various nanoparticles (NPs) have been used as supporting matrices and carriers for enzyme immobilization. Among the NPs, in recent years, green magnetic nanoparticles (GMNPs) have attracted great attention as ideal support material for enzyme immobilization owing to their exceptional properties, such as their easy preparation, low toxicity, biocompatibility, and lower diffusion limitation. These properties enable the immobilized enzymes on GMNPs to be used in many different applications. This chapter aims to summarize the recent developments about enzyme immobilization on magnetic nanoparticles and GMNPs and their practical applications. © 2024 Elsevier B.V., All rights reserved.