Scopus İndeksli Yayınlar Koleksiyonu
Permanent URI for this collectionhttps://hdl.handle.net/20.500.12573/395
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Conference Object Generating Lost Urban Fabric: Exploration of Generative Adversarial Networks as a Design Tool in Post-Disaster Urban Recovery(Education and Research in Computer Aided Architectural Design in Europe, 2025) Takış, F.N.; Akyüz, S.This study investigates the use of GANs, particularly the Pix2PixHD, for reconstructing urban fabric and preserving urban memory in post-disaster contexts, focusing on Hatay, Türkiye, after the 2023 earthquakes. Models were trained on pre-disaster urban maps and tested on incomplete post-earthquake data to regenerate damaged urban areas. Evaluation metrics, including FID scores, SSIM values, and visual inspections, demonstrated the model's ability to produce contextually accurate designs. The trained model effectively maintained road networks, building geometries, and spatial coherence. In addition to spatial consistency, the model produced outputs with sharp edges and high visual clarity. These results highlight the significant potential of GANs as generative design tools, offering valuable support to urban planners and architects in balancing urgent reconstruction needs with the long-term preservation of urban identity and memory in disaster-affected areas. © 2025, Education and research in Computer Aided Architectural Design in Europe. All rights reserved.Article Deep-Learning Detection of Open-Apex Teeth on Panoramic Radiographs Using YOLO Models(Springer, 2025-12-23) Edik, Merve; Celebi, Fatma; Cukurluoglu, AykaganObjectivesThe use of deep learning in detecting teeth with open apices can prevent the need for additional radiographs for patients. The presented study aims to detect open-apex teeth using You Only Look Once (YOLO)-based deep learning models and compare these models.MethodsA total of 966 panoramic radiographs were included in the study. Open-apex teeth in panoramic radiographs were labeled. During the labeling process, they were divided into 6 classes in the maxilla and mandible, namely incisors, premolars, and molars. AI models YOLOv3, YOLOv4, and YOLOv5 were used. To evaluate the performance of the three detection models, both overall and separately for each class in the test dataset, precision, recall, average precision (mAP), and F1 score were calculated.ResultsYOLOv4 achieved the highest overall performance with a mean average precision (mAP) of 87.84% at IoU (Intersection over Union) 0.5 (mAP@0.5), followed by YOLOv5 with 85.6%, and YOLOv3 with 84.46%. Regarding recall, YOLOv4 also led with 90%, while both YOLOv3 and YOLOv5 reached 89%. Moreover, the F1 score was the highest for YOLOv4 (0.87), followed by YOLOv3 (0.86) and YOLOv5 (0.85).ConclusionsIn this study, YOLOv3, YOLOv4, and YOLOv5 were evaluated for the detection of open-apex teeth, and their mAP, recall, and F1 scores exceeded 84%. Deep learning-based systems can provide faster and more accurate results in the detection of open-apex teeth. This may help reduce the need for additional radiographs from patients and aid dentists by saving time.Article G-C3N4@Fe3O4 Nanomaterial Synthesis for Magnetic Solid-Phase Extraction and Photocatalytic Removal of Basic Blue 3(Springer Heidelberg, 2025-12-16) Kizil, Nebiye; Kayaci, Nilgun; Erbilgin, Duygu Erkmen; Yola, Mehmet Lutfi; Yilmaz, Erkan; Soylak, MustafaThe present research synthesized a g-C3N4@Fe3O4 hybrid material for efficient magnetic solid-phase extraction (MSPE) and photocatalytic degradation of Basic Blue 3 (BB3) dye from wastewater. Characterization of the synthesized g-C3N4@Fe3O4 was conducted through Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), scanning electron microscopy (SEM), and energy-dispersive X-ray spectroscopy (EDX). The optimization of the method was carried out by examining parameters such as pH, g-C3N4@Fe3O4 amount, sample volume, and adsorption/desorption duration. In addition, analytical performance criteria such as limit of detection (LOD), limit of quantification (LOQ), and relative standard deviation (RSD) of the MSPE method were calculated as 1.29 mu g L-1, 4.28 mu g L-1, and 1.9%, respectively. The method was applied to real samples, including wastewater and textiles, and validated through addition/recovery studies for the magnetic solid-phase extraction procedure. The recoveries were gained between 91 and 100%. The reusability synthesized g-C3N4@Fe3O4 was also evaluated. The recoveries for Basic Blue 3 dye decreased to 81% after the fourth experiment. Furthermore, the photocatalytic performance of the g-C3N4@Fe3O4 hybrid material was evaluated due to its good surface area and strong interaction with Basic Blue 3 dye. The photocatalytic activity of g-C3N4@Fe3O4 hybrid material was calculated as 96.8% for 100 mg in 300 min.Conference Object Shooting a Water Slug Into an Air Column with and without Vent(Amer Soc Mechanical Engineers, 2025-07-20) Bozkus, Zafer; Dincer, Ali Ersin; Tijsseling, Arris S.; van de Ven, FonsCompressed air is used to shoot a single water slug into an upward sloping pipe with elbow and orifice at its upper end. The experiment concerns a 12 m long pipe of 0.1 m diameter connected to a 0.5 m3 air vessel. The 10 to 50 kg heavy slugs are initially at rest in the lower part of the system. Because the upper end is closed by a flange with orifice, the water slug is expected not to hit the upstream elbow. It causes - like a piston - a fast compression of the air column ahead of it. Sometimes the slug bounces back and forth, which results in a pressure oscillation of serious amplitude. Numerical simulations based on an elementary mathematical model are normally used to interpret the pressure measurements, not all of which are fully understood. Lessons learned are summarised, and suggestions for improved experiments and enhanced simulations are given. The research is of importance, for example, for steam lines where liquid condensates may collect in lower parts after power failure. Start-up of the system will then lead to rapid slug acceleration and potentially damaging impact on elbows, orifices, and machinery.Article Does Your Love Lift Me Higher? A Direct Replication of the Energising Role of Secure Relationships(John Wiley & Sons Ltd, 2025-12-07) Lagap, Adar Cem; Harma, MehmetPrevious work has revealed that priming people with significant others increases feelings of security and energy, and in turn, boosts exploration motivations. In this preregistered study, we directly replicated Luke et al.'s (2012) Study 2 (N = 281). We found similar results as the replicated study regarding increased security feelings and exploration motivations on the self-report measures after the priming. However, we did not find any support for the increased energy feelings after the attachment security priming. In addition, contrary to Luke et al.'s (2012) results, energy feelings did not mediate the relationship between security priming and exploration motivations. A discussion of null findings, along with the limitations of self-reports and potential misinterpretation of the mediational analyses, follows. We also discuss possible future implications of the current findings.Book Part Design and Analysis of a Solar-Assisted Combined Cooling, Heating, and Power System for Smart Cities: Case Study From Doha(IGI Global, 2025-08-22) Akroot, A.; Almohammedi, A.A.; Talal, W.The rising demand for sustainable and energy-efficient solutions in urban areas has driven interest in renewable systems for smart cities. This chapter presents a solar-assisted combined cooling, heating, and power (SA-CCHP) system designed for Doha, Qatar, where high solar radiation and cooling needs prevail. Powered solely by a parabolic trough collector (PTC) field, the system delivers net power from 1200 kW in winter to 195 kW in summer, with cooling loads of ~2100-3400 kW and heating loads of ~90)00-14500 kW. Increasing the superheating degree at the ORC turbine inlet enhances power and heating but reduces cooling, while raising the pressure ratio (A) from 0.5 to 0.8 boosts net output and efficiency, cutting CO2 emissions from 0.22 to 0.13 kg/kWh. Overall energy efficiency rises from 85% to 90% and exergy efficiency from 76% to 78.5%, while costs decline from $40/hr to $36/hr, confirming both environmental and economic viability. The study demonstrates the feasibility of solar-powered CCHP systems as scalable models for achieving clean energy goals in smart cities. © 2026, IGI Global Scientific Publishing. All rights reserved.Conference Object Fully Flexible, Low-Cost, Environmentally Friendly Yarn-Based Inp/Ag Nw Photodetectors for UV-Visible Light Detection(SPIE, 2025-08-01) Savaş, M.; Akrema, A.; Ocal, S.K.; Erdem, T.We report the fabrication and investigate of a novel photodetector using a heterostructure of InP quantum dots (QDs) and silver nanowires (Ag NWs) incorporated into yarn. This device is simple, scalable, low-cost, flexible, and functions under ambient conditions. Ag NWs and red-emitting InP QDs were separately synthesized via chemical methods and mixed in a specific ratio to coat functional yarns, which were then knitted into fabrics. The photodetector benefits from the excellent electrical conductivity of Ag NWs and the strong optical absorption of InP QDs. It shows enhanced photoelectric response in both UV and visible regions. At 405 nm illumination, the device achieves a photoresponsivity of 5.8 mA W-1 and a detectivity of 2 × 1010 Jones-values comparable to or exceeding those of similar devices. The enhanced performance is attributed to efficient charge transfer enabled by favorable band alignment between Ag NWs and InP QDs, along with synergistic effects from nanostructure dimensionality and quantum confinement. The device's combination of flexibility, sensitivity, and cost-efficiency makes it a strong candidate for wearable UV-visible photodetectors. © 2025 SPIE. All rights reserved.Conference Object Minimising the Cycle Time with Assembly Line Balancing and Worker Assignment: A Case Study in a Medical Device Manufacturer Company(ISRES Publishing, 2025-10-27) Kayser, A.; Sipahi, G.; Sevimli, O.; Toplu, N.; Turan, S.; Satic, U.In this research, we considered the mixed-model assembly line balancing and worker assignment problems of a medical device manufacturer in Türkiye. We combined these problems into a single integer programming model where multiple types of products can be assembled simultaneously on a single assembly line, and workers are assigned to workstations based on their abilities while ensuring the balance and efficiency of the assembly line. Our proposed approach seeks to minimise the cycle time and ability-based assignment costs on the assembly line. We used the Gurobi solver to find the optimal solution for the proposed problem. Our approach provides higher efficiency and results in a 76% increase in productivity without requiring additional work hours or workers. © 2025 Published by ISRES Publishing.Conference Object Scheduling in Flexible Flow Shop Environments with Re-Entrant Jobs and Heterogeneous Workers(ISRES Publishing, 2025-10-27) Bekli, S.; Kayisoglu, B.In many industries, manufacturing is organized as a flexible flow shop (FFS), which has gotten the researchers' attention. The scheduling studies, particularly those on FFS scheduling, are concerned with homogeneous workers with the same skill set or heterogeneous workers who can only perform one specific type of operation on the production lines. Moreover, jobs are mainly assumed to go through an operation once. Yet, in real-life production, workers might have different skill sets with varying processing times. Furthermore, certain jobs may require revisiting the same machine multiple times, i.e., re-entrant jobs. We study an FFS environment with re-entrant jobs, considering worker flexibility. We propose a mixed integer linear programming model to find the optimal sequences of jobs to be processed by the multiskilled workers assigned to the production system, ensuring each re-entrant job waits for a predefined time window before reprocessing on the same operation. The objective of the model is to minimize makespan. We tested the proposed model on a dataset taken from a real production system of a PVC windows and doors production facility. © 2025 Published by ISRES Publishing.Article Citation - WoS: 2Citation - Scopus: 2Neuroinflammatory Human Brain Organoids Enable Comprehensive Drug Screening Studies: Fingolimod and Its Analogues in Focus(Bentham Science Publishing Ltd, 2025-10-08) Acar, Busra; Pepe, Nihan Aktas; Zivkovic, Aleksandra; Stark, Holger; Sen, AlaattinIntroduction The absence of physiologically relevant models for neuroinflammatory brain disorders, such as multiple sclerosis (MS), highlights the need for improved drug screening platforms. To bridge this gap, this study aimed to develop a human brain organoid (hBO) model incorporating essential neural cell types, including astrocytes, microglia, and oligodendrocytes.Methods hBOs were generated from H9 stem cells, and neuroinflammatory characteristics were elicited by lipopolysaccharide (LPS). The expression of specific neuronal and inflammatory markers was assessed through qRT-PCR, immunofluorescence staining (IFS), and ELISA.Results IFS of mature hBOs with anti-SOX2, anti-SATB2, anti-MAPT, anti-GFAP, anti-MBP, and anti-IBA1 antibodies and images collected with the confocal microscope confirmed the differentiation of H9 cells into cortical neurons, astrocytes, microglia, and oligodendrocyte cell types. Elevated GFAP, IBA1, NF-kappa B, and IL-6 levels, along with reduced CNPase expression with LPS treatment, were considered reflective of MS-like pathology and were used to test fingolimod and its derivatives. Fingolimod and all its derivatives, specifically ST-1505, decreased MAPT (2.1-fold in ELISA, 1.7-fold in IFS), GFAP (1.8-fold in IFS), TNF alpha (5.4-fold in qRT-PCR), and FABP (1.5-fold in ELISA) levels, and increased IL-10 (11-fold in qRT-PCR) and MBP (2.9-fold in IFS) levels.Discussion The present data collectively showed LPS to evoke neuroinflammation in the hBO model, while fingolimod and its derivatives, particularly ST-1505, exhibited significant anti-inflammatory and neuroprotective properties by counteracting these evoked changes in the hBO model.Conclusion The findings supported the applicability of brain organoids as a model system for drug screening studies for neuroinflammatory brain diseases.
