PubMed İndeksli Yayınlar Koleksiyonu

Permanent URI for this collectionhttps://hdl.handle.net/20.500.12573/397

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Citation - WoS: 2
Citation - Scopus: 1
Computational Prediction of MicroRNAs in Histoplasma Capsulatum
(Academic Press Ltd- Elsevier Science Ltd, 2020) Demirci, Mueserref Duygu Sagar
MicroRNAs (miRNAs) are small and non-coding RNAs that regulate gene expression through post-transcriptional regulation. Although, the standard miRNA repository, MiRBase, lists more than 200 organisms having miRNA mediated regulation mechanism and thousands of miRNAs, there is not enough information about miRNAs of fungal species. Considering that there are various fungal pathogens causing disease phenotypes, it is important to search for miRNAs of those organisms. The leading cause of endemic mycosis in the USA is a fungal disease known as histoplasmosis, which is resulted by infection with a fungal intracellular parasite, Histoplasma capsulatum (H. capsulatum). In this work, genomes of H. capsulatum strains NAm1 and G217B were explored for potential miRNA like sequences and structures. Through a complex workflow involving miRNA detection and target prediction, several miRNA candidates of H. capsulatum and their possible targets in human were identified. The results presented here indicate that H. capsulatum might be one of the fungal pathogens having a miRNA based post-transcriptional gene regulation mechanism and it might have a miRNA mediated host - parasite interaction with human.
Citation - WoS: 130
Citation - Scopus: 143
Analyzing the Nexus Between Energy Transition, Environment and ICT: A Step Towards COP26 Targets
(Academic Press Ltd- Elsevier Science Ltd, 2023) Tzeremes, Panayiotis; Dogan, Eyup; Alavijeh, Nooshin Karimi
In line with the Sustainable Development Goals and the recent COP26 summit, energy transition, low carbon emissions and technology have become extremely important subjects in the agenda of governments and poli-cymakers. The present study thus discusses the nexus between energy transition, economic growth, CO2 emis-sions and information and communications technology (ICT) in BRICS countries applying the novel GMM-PVAR method proposed on the annual data for the period 2000-2017. This method is strong to the issue of endogeneity which is commonly faced in the context of panel data analysis but mostly ignored in the literature. The findings of this research demonstrate that carbon emissions have a positive and significant effect on energy transition; similarly, raising economic growth augments the consumption of energy transition. Furthermore, ICT is found to be a significant choice in the development of energy transition and the solution of environmental challenges. Overall, technological factors in addition to economic and environmental factors also have great roles in the development of renewable energy and energy transition. Thus, results from this study call for government supports to develop ICT across the BRICS countries.
Citation - WoS: 65
Analysis of the Best Available Techniques for Wastewaters from a Denim Manufacturing Textile Mill
(Academic Press Ltd- Elsevier Science Ltd, 2017) Yukseler, H.; Uzal, N.; Sahinkaya, E.; Kitis, M.; Dilek, F. B.; Yetis, U.
The present study was undertaken as the first plant scale application and evaluation of Best Available Techniques (BAT) within the context of the Integrated Pollution Prevention and Control/Industrial Emissions Directive to a textile mill in Turkey. A "best practice example" was developed for the textile sector; and within this context, BAT requirements for one of the World's leading denim manufacturing textile mills were determined. In order to achieve a sustainable wastewater management; firstly, a detailed wastewater characterization study was conducted and the possible candidate wastewaters to be reused within the mill were identified. A wastewater management strategy was adopted to investigate the possible reuse opportunities for the dyeing and finishing process wastewaters along with the composite mill effluent. In line with this strategy, production processes were analysed in depth in accordance with the BAT Reference Document not only to treat the generated wastewaters for their possible reuse, but also to reduce the amount of water consumed and wastewater generated. As a result, several applicable BAT options and strategies were determined such as reuse of dyeing wastewaters after treatment, recovery of caustic from alkaline finishing wastewaters, reuse of biologically treated composite mill effluent after membrane processes, minimization of wash water consumption in the water softening plant, reuse of concentrate stream from reverse osmosis plant, reducing water consumption by adoption of counter-current washing in the dyeing and finishing processes. The adoption of the selected in-process BAT options for the minimization of water use provided a 30% reduction in the total specific water consumption of the mill. The treatability studies adopted for both segregated and composite wastewaters indicated that nanofiltration is satisfactory in meeting the reuse criteria for all the wastewater streams considered. (C) 2017 Elsevier Ltd. All rights reserved.
Citation - WoS: 42
Citation - Scopus: 44
Evaluation of the Neutralization Performances of the Industrial Waste Products (IWPS) in Sulphide-Rich Environment of Cemented Paste Backfill
(Academic Press Ltd- Elsevier Science Ltd, 2020) Yilmaz, Tekin; Ercikdi, Bayram; Cihangir, Ferdi
The purpose of this research is to examine the neutralization performances of CaO-rich industrial waste products (IWPs) in the sulphide-rich environment of cemented paste backfill (CPB). A total of 205 CPB samples were prepared by using four different IWPs (type-C fly ash (C-FA), blast furnace slag (BFS), calcitic limestone (CL) and dolomitic limestone (DL)) as 5, 10 and 15 wt% substitute for sulphide-rich tailings. These CPB samples were cured and subjected to the acid (pH) and sulphate (SO42-) tests during 7-360 days of curing periods. MIP and XRD tests were also carried out to understand the generation of acid and sulphate and their effect on CPB stability at 28 and 180 days. The findings indicated that the utilisation of IWPs in CPB mixtures mitigated the acid (up to 58.9% higher pH values) and sulphate (up to 72.1% lower SO42- ion release) production, and enhanced the microstructure (12.43% lower total porosity) of CPBs owing to the neutralization potential, pore-filling effect, pozzolanic and partially binding characteristics of IWPs. It can be inferred from these findings that the IWPs can be suitably utilised as neutralization materials in CPB of sulphide-rich tailings. This in turn allows the mitigation of potential disposal/pollution problems associated with these IWPs.
Citation - WoS: 9
Citation - Scopus: 11
Unravelling the Moderating Roles of Environmental Regulations on the Impact of Foreign Direct Investment on Environmental Sustainability
(Academic Press Ltd- Elsevier Science Ltd, 2025) Ehigiamusoe, Kizito Uyi; Chen, Danqing; Dogan, Eyup; Binsaeed, Rima H.
In the era of economic globalization, China attracts significant foreign direct investment (FDI) to accelerate economic prosperity. FDI inflows could have ramifications on environmental degradation (ED) despite the enactment of different environmental regulations (ERs) such as market-incentive, command-and-control as well as informal regulations. Though some studies have shown that FDI and ED have significant relationship, the moderating roles of different ERs on the environmental impact of FDI has not been empirically unraveled. This study fills this research gap by analyzing the direct impact of FDI on ED (i.e., carbon dioxide emissions, ecological footprint) using the provincial panel data. Second, it unravels the moderating roles of different ERs on the environmental impact of FDI in the provinces and regions. The results indicate that FDI directly mitigates ED, verifying the pollution halo hypothesis while ERs directly alleviate ED in China. However, the interaction between FDI and ERs do not alleviate ED in China albeit regional heterogeneity exist. The economic implication is that FDI is not a channel through which ERs enhance environmental sustainability in China. This study recommends some policy options arising from the findings.
Citation - WoS: 179
Citation - Scopus: 190
The Role of Economic Policy Uncertainty in the Energy-Environment Nexus for China: Evidence From the Novel Dynamic Simulations Method
(Academic Press Ltd- Elsevier Science Ltd, 2021) Amin, Azka; Dogan, Eyup
Even though a great number of researches have explored the determinants of carbon emissions, the impact of economic policy uncertainty (EPU) on the environment has not been fully investigated in the energy-environment literature. Since recent studies show a strong relationship between the external environment and uncertainty, the present study for the first time in the literature aims to explore the function of EPU in the energy-environment nexus for China by using the novel bounds testing with dynamic simulations. The empirical results indicate that increases in the real income and energy intensity contribute to environmental pollution while increases in renewable energy lower the level of emissions. Besides, an increase in EPU causes an increase in the volume of carbon emissions. As EPU increases, the government's attention to implement environmental protection policies decreases, and the execution of the environment-related strategies is likely directed in an expected way. The empirical findings suggest that the government should establish consistency in economic and environmental policies to mitigate environmental pollution and thus to reach environmental sustainability.
Citation - WoS: 13
Citation - Scopus: 14
How Does Technological Innovation Moderate the Environmental Impacts of Economic Growth, Natural Resource Rents and Trade Openness
(Academic Press Ltd- Elsevier Science Ltd, 2024) Ehigiamusoe, Kizito Uyi; Dogan, Eyup; Ramakrishnan, Suresh; Binsaeed, Rima H.
The objective of this study is to unravel the linear impacts of economic growth, technological innovation, natural resource rents and trade openness on carbon emissions in Malaysia during 1980-2021. It also unveils the moderating role of technological innovation on the impacts of economic growth, natural resource rents and trade openness on carbon emissions. It further analyses the nonlinear relationship between technological innovation and carbon emissions. It estimates the parameters with the Autoregressive Distributed Lag model technique. The results of the linear model reveal that economic growth, natural resource rents and trade openness contributes to carbon emissions while technological innovation mitigates carbon emissions. The disaggregated analysis of natural resource rents indicates that oil rents, natural gas rents and coal rents intensify carbon emissions while mineral rents and forest rents do not contribute to carbon emissions. The disaggregated analysis of trade openness shows that exports worsen carbon emissions while imports have tenuous effect. The disaggregated analysis of technological innovation indicates that innovation by non-residents mitigate carbon emissions while innovation by residents do not alleviate carbon emissions. Moreover, evidence from the interaction model reveals that technological innovation can favourably mitigate the adverse impacts of economic growth and trade openness on carbon emissions albeit it cannot alleviate the impact of natural resource rents on carbon emissions. Besides, the nonlinear model indicates a U-shaped relationship between technological innovation and carbon emissions. Unlike previous studies that typically focused on the direct impacts of these variables, this study unravels the impacts of the disaggregated components as well as provides insights into the moderating and nonlinear effects of technological innovation on carbon emissions. The implication of this study is that efforts to achieve a carbon-neutral economy should consider the direct and indirect impacts of economic growth, technological innovation, natural resource rents and trade openness. It is recommended for Malaysia to encourage technological innovation in her quest to abate the adverse environmental impacts of economic activities.
Citation - WoS: 12
Citation - Scopus: 15
Ecological Footprints and Sustainable Environmental Management: A Critical View of China's Economy
(Academic Press Ltd- Elsevier Science Ltd, 2023) Li, Menghan; Badeeb, Ramez Abubakr; Dogan, Eyup; Gu, Xiao; Zhang, Hong
Global economies have recently been concerned about sustainable environmental management by reducing emissions and tackling ecological footprints. The rapid economic expansion and investment in traditional manufacturing further raises environmental degradation. China surpasses other emerging economies in the economic growth race yet has remained the top pollution-emitting economy for the last few decades, necessitating scholarly attention. This study examines the influencing factors of ecological footprints in China from the perspective of COP27. Using the extended dataset from 1988 to 2021, this study uses several time series diagnostic tests and verifies the existence of the long-run association between the study variables. Consequently, the non-linear scattered data leads to non-parametric (method of moment quantile regression) adoption. The empirical results indicate that only economic growth is a significant factor in environmental quality degradation in China. However, improving renewable energy usage, research and development, and foreign direct investment reduces the country's ecological footprint. Hence, the latter variables substantially lead to environmental sustainability. The robustness of the results is confirmed via a robust non-parametric estimator and causality test. Based on the empirical results, this study recommends increased investment in research and development, renewable production, and foreign direct investment enhancement.

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