An Effective Colorectal Polyp Classification for Histopathological Images Based on Supervised Contrastive Learning

dc.contributor.author Yengec-Tasdemir, Sena Busra
dc.contributor.author Aydin, Zafer
dc.contributor.author Akay, Ebru
dc.contributor.author Doǧan, Serkan
dc.contributor.author Yilmaz, Bulent
dc.date.accessioned 2025-09-25T10:40:24Z
dc.date.available 2025-09-25T10:40:24Z
dc.date.issued 2024
dc.description.abstract Early detection of colon adenomatous polyps is pivotal in reducing colon cancer risk. In this context, accurately distinguishing between adenomatous polyp subtypes, especially tubular and tubulovillous, from hyperplastic variants is crucial. This study introduces a cutting-edge computer-aided diagnosis system optimized for this task. Our system employs advanced Supervised Contrastive learning to ensure precise classification of colon histopathology images. Significantly, we have integrated the Big Transfer model, which has gained prominence for its exemplary adaptability to visual tasks in medical imaging. Our novel approach discerns between in-class and out-of-class images, thereby elevating its discriminatory power for polyp subtypes. We validated our system using two datasets: a specially curated one and the publicly accessible UniToPatho dataset. The results reveal that our model markedly surpasses traditional deep convolutional neural networks, registering classification accuracies of 87.1% and 70.3% for the custom and UniToPatho datasets, respectively. Such results emphasize the transformative potential of our model in polyp classification endeavors. © 2024 Elsevier B.V., All rights reserved. en_US
dc.description.sponsorship This work was supported by the Scientific and Technological Research Council of Türkiye (TUBITAK) under Grant 120E204. The authors would like to thank Serdal Sadet Ozcan for her valuable contribution to detailed labeling of the dataset. This study was conducted ethically based on the standards of the Declaration of Helsinki, and it has been approved by Erciyes University, the Clinical Research Ethics Committee. We ensured that all research procedures adhered to the accepted ethical standards. The committee's approval on October 9, 2019, with the reference number 96 681 246, confirmed that our experimental protocols were thoroughly evaluated and endorsed by the appropriate institutional body. Before participation, all subjects participating in this study were comprehensively informed about the research objectives, the procedures to be followed, potential risks, and the benefits that could arise from their participation. Following this briefing, informed voluntary consent was obtained from each participant. This meticulous process was designed to ensure that participants were fully aware of their rights and the nature of the research being conducted, thereby preserving their autonomy and well-being throughout the study. In line with our commitment to ethical conduct, we have taken strict measures to ensure the rights to privacy of human subjects at all times. All the participants’ personal data that were to be collected in the course of the study were treated with maximum confidentiality and used for this research alone. Identifiable information had been appropriately either anonymized or pseudonymized, and strict access was limited to the research team only, hence protecting all participants from the breach of either their privacy or integrity.
dc.description.sponsorship This work was supported by the Scientific and Technological Research Council of Turkey (TUBITAK) under Grant 120E204 .
dc.description.sponsorship Türkiye Bilimsel ve Teknolojik Araştırma Kurumu, TÜBİTAK, (120E204); Türkiye Bilimsel ve Teknolojik Araştırma Kurumu, TÜBİTAK; Erciyes Üniversitesi, (96 681 246); Erciyes Üniversitesi
dc.identifier.doi 10.1016/j.compbiomed.2024.108267
dc.identifier.issn 1879-0534
dc.identifier.issn 0010-4825
dc.identifier.scopus 2-s2.0-85187543033
dc.identifier.uri https://doi.org/10.1016/j.compbiomed.2024.108267
dc.identifier.uri https://hdl.handle.net/20.500.12573/3247
dc.language.iso en en_US
dc.publisher Elsevier Ltd en_US
dc.relation.ispartof Computers in Biology and Medicine en_US
dc.rights info:eu-repo/semantics/openAccess en_US
dc.subject Big Transfer en_US
dc.subject Colonic Polyp Classification en_US
dc.subject Computer-Aided Diagnosis en_US
dc.subject Histopathology Image Classification en_US
dc.subject Supervised Contrastive Learning en_US
dc.subject Transfer Learning en_US
dc.subject Classification (Of Information) en_US
dc.subject Computer Aided Diagnosis en_US
dc.subject Computer Aided Instruction en_US
dc.subject Convolutional Neural Networks en_US
dc.subject Deep Neural Networks en_US
dc.subject Transfer Learning en_US
dc.subject Vision en_US
dc.subject Big Transfer en_US
dc.subject Colonic Polyp Classification en_US
dc.subject Colonic Polyps en_US
dc.subject Colorectal Polyps en_US
dc.subject Histopathological Images en_US
dc.subject Histopathology Image Classification en_US
dc.subject Image-Based en_US
dc.subject Images Classification en_US
dc.subject Supervised Contrastive Learning en_US
dc.subject Image Classification en_US
dc.subject Adult en_US
dc.subject Aged en_US
dc.subject Article en_US
dc.subject Cancer Classification en_US
dc.subject Colorectal Polyp en_US
dc.subject Convolutional Neural Network en_US
dc.subject Diagnostic Imaging en_US
dc.subject Female en_US
dc.subject Histopathology en_US
dc.subject Human en_US
dc.subject Human Tissue en_US
dc.subject Major Clinical Study en_US
dc.subject Male en_US
dc.subject Receiver Operating Characteristic en_US
dc.subject Adenomatous Polyp en_US
dc.subject Artificial Neural Network en_US
dc.subject Colon Polyp en_US
dc.subject Computer Assisted Diagnosis en_US
dc.subject Procedures en_US
dc.subject Adenomatous Polyps en_US
dc.subject Colonic Polyps en_US
dc.subject Diagnosis, Computer-Assisted en_US
dc.subject Diagnostic Imaging en_US
dc.subject Humans en_US
dc.subject Neural Networks, Computer en_US
dc.title An Effective Colorectal Polyp Classification for Histopathological Images Based on Supervised Contrastive Learning en_US
dc.type Article en_US
dspace.entity.type Publication
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gdc.coar.type text::journal::journal article
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gdc.description.department Abdullah Gül University en_US
gdc.description.departmenttemp [Yengec-Tasdemir] Sena Busra, Electrical Engineering and Computer Science, Queen's University Belfast, Belfast, United Kingdom; [Aydin] Zafer, Department of Electrical & Computer Engineering, Abdullah Gül Üniversitesi, Kayseri, Turkey, Department of Computer Engineering, Abdullah Gül Üniversitesi, Kayseri, Turkey; [Akay] Ebru, Pathology Clinic, Kayseri City Hospital, Kayseri, Turkey; [Doǧan] Serkan, Gastroenterology Clinic, Kayseri City Hospital, Kayseri, Turkey; [Yilmaz] Bulent, Department of Electrical & Computer Engineering, Abdullah Gül Üniversitesi, Kayseri, Turkey, Department of Electrical Engineering, Gulf University for Science and Technology Kuwait, Hawally, Kuwait en_US
gdc.description.publicationcategory Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı en_US
gdc.description.scopusquality Q1
gdc.description.volume 172 en_US
gdc.description.wosquality Q1
gdc.identifier.openalex W4392579088
gdc.identifier.pmid 38479197
gdc.index.type Scopus
gdc.index.type PubMed
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gdc.oaire.keywords Diagnostic Imaging
gdc.oaire.keywords Colonic Polyps
gdc.oaire.keywords Computer-aided diagnosis
gdc.oaire.keywords Big transfer
gdc.oaire.keywords Supervised contrastive learning
gdc.oaire.keywords Transfer learning
gdc.oaire.keywords Adenomatous Polyps
gdc.oaire.keywords Histopathology image classification
gdc.oaire.keywords Humans
gdc.oaire.keywords Neural Networks, Computer
gdc.oaire.keywords Diagnosis, Computer-Assisted
gdc.oaire.keywords Colonic polyp classification
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gdc.oaire.sciencefields 0301 basic medicine
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gdc.oaire.sciencefields 03 medical and health sciences
gdc.oaire.sciencefields 0202 electrical engineering, electronic engineering, information engineering
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gdc.opencitations.count 9
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gdc.scopus.citedcount 13
gdc.virtual.author Aydın, Zafer
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