Rational Design of EDTA-Incorporated Nanoflowers as Novel and Effective Endodontic Disinfection Against Biofilms

dc.contributor.author Aslan, Tugrul
dc.contributor.author Dadi, Seyma
dc.contributor.author Kafdag, Ozgur
dc.contributor.author Temur, Nimet
dc.contributor.author Ildiz, Nilay
dc.contributor.author Ocsoy, Ismail
dc.contributor.author Ustun, Yakup
dc.date.accessioned 2025-09-25T10:56:16Z
dc.date.available 2025-09-25T10:56:16Z
dc.date.issued 2024
dc.description Ildiz, Nilay/0000-0002-3799-856X; Ustun, Yakup/0000-0002-9290-5661 en_US
dc.description.abstract The ethylenediaminetetradiacetic acid (EDTA) is one of the most commonly used irrigation solutions. Although EDTA has a very low antimicrobial property, it is used to remove inorganic part of smear layer in areas of root canal system. Herein, we developed EDTA-incorporated nanoflowers (EDTA NFs), for the first time, as novel and effective irrigation solution with quite high antimicrobial property to provide complete disinfection in root canal system. We both systematically elucidated the formation of the EDTA NFs with various techniques, and their catalytic and antimicrobial activities in the presence of hydrogen peroxide (H2O2) were documented through intrinsic EDTA property and peroxidase-like activities. en_US
dc.description.sponsorship This work was supported by grants from the Erciyes University Scientific Research Office (TSA-2018-8023). [TSA-2018-8023]; Erciyes University Scientific Research Office en_US
dc.description.sponsorship This work was supported by grants from the Erciyes University Scientific Research Office (TSA-2018-8023). en_US
dc.identifier.doi 10.1007/s10266-023-00857-2
dc.identifier.issn 1618-1247
dc.identifier.issn 1618-1255
dc.identifier.scopus 2-s2.0-85173103698
dc.identifier.uri https://doi.org/10.1007/s10266-023-00857-2
dc.identifier.uri https://hdl.handle.net/20.500.12573/4536
dc.language.iso en en_US
dc.publisher Springer en_US
dc.relation.ispartof Odontology en_US
dc.rights info:eu-repo/semantics/closedAccess en_US
dc.subject Edta Nanoflowers en_US
dc.subject Catalytic Activity en_US
dc.subject Endodontic Disinfection en_US
dc.subject Biofilms en_US
dc.title Rational Design of EDTA-Incorporated Nanoflowers as Novel and Effective Endodontic Disinfection Against Biofilms en_US
dc.type Article en_US
dspace.entity.type Publication
gdc.author.id Ildiz, Nilay/0000-0002-3799-856X
gdc.author.id Ustun, Yakup/0000-0002-9290-5661
gdc.author.scopusid 55336754100
gdc.author.scopusid 57219312593
gdc.author.scopusid 57201292096
gdc.author.scopusid 57847994200
gdc.author.scopusid 57188707417
gdc.author.scopusid 37017685100
gdc.author.scopusid 37017685100
gdc.author.wosid Ildiz, Nilay/Aaj-9263-2021
gdc.author.wosid Temur, Nimet/Odl-0565-2025
gdc.author.wosid Üstün, Yakup/Aaf-2749-2019
gdc.author.wosid Aslan, Tugrul/Aao-6269-2021
gdc.author.wosid Ustun, Yakup/M-9527-2014
gdc.bip.impulseclass C4
gdc.bip.influenceclass C5
gdc.bip.popularityclass C4
gdc.coar.access metadata only access
gdc.coar.type text::journal::journal article
gdc.collaboration.industrial false
gdc.description.department Abdullah Gül University en_US
gdc.description.departmenttemp [Aslan, Tugrul; Kafdag, Ozgur; Ustun, Yakup] Erciyes Univ, Fac Dent, Dept Endodont, Kayseri, Turkiye; [Dadi, Seyma] Abdullah Gul Univ, Dept Nanotechnol Engn, TR-38080 Kayseri, Turkiye; [Temur, Nimet; Ocsoy, Ismail] Erciyes Univ, Fac Pharm, Dept Analyt Chem, TR-38039 Kayseri, Turkiye; [Ildiz, Nilay] Bandirma Onyedi Eylul Univ, Vocat Sch Hlth Serv, Med Imaging Dept, TR-10200 Bandirma, Turkiye en_US
gdc.description.endpage 452 en_US
gdc.description.issue 2 en_US
gdc.description.publicationcategory Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı en_US
gdc.description.scopusquality Q1
gdc.description.startpage 444 en_US
gdc.description.volume 112 en_US
gdc.description.woscitationindex Science Citation Index Expanded
gdc.description.wosquality Q2
gdc.identifier.openalex W4387296241
gdc.identifier.pmid 37787827
gdc.identifier.wos WOS:001076956900001
gdc.index.type WoS
gdc.index.type Scopus
gdc.index.type PubMed
gdc.oaire.diamondjournal false
gdc.oaire.impulse 7.0
gdc.oaire.influence 2.6847524E-9
gdc.oaire.isgreen false
gdc.oaire.keywords Disinfection
gdc.oaire.keywords Anti-Infective Agents
gdc.oaire.keywords Root Canal Irrigants
gdc.oaire.keywords Sodium Hypochlorite
gdc.oaire.keywords Smear Layer
gdc.oaire.keywords Biofilms
gdc.oaire.keywords Humans
gdc.oaire.keywords Hydrogen Peroxide
gdc.oaire.keywords Dental Pulp Cavity
gdc.oaire.keywords Edetic Acid
gdc.oaire.keywords Root Canal Preparation
gdc.oaire.popularity 7.3129223E-9
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gdc.openalex.collaboration National
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gdc.openalex.toppercent TOP 10%
gdc.opencitations.count 4
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