Yüksek Lisans Tezleri
Permanent URI for this collectionhttps://hdl.handle.net/20.500.12573/5799
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Master Thesis İnsan Bağırsak Mikrobiyotasından Hastalık Biyobelirteçlerinin Tespiti için Makine Öğrenmesi Temelli Sistem Geliştirilmesi(Abdullah Gül Üniversitesi, Fen Bilimleri Enstitüsü, 2024) Koçak, Ayşegül; Güngör, Burcu; Yousef, MalikThe human gut microbiota consists of a diverse ecosystem of organisms, encompasses billions of species. Recently developed next-generation sequencing methods have enabled researchers to examine the microbiota in greater detail, leading to new insights into its functions and dysfunctions. This study aims to identify metagenomic biomarkers (Microorganism-Enzyme Pairs) for colorectal cancer (CRC). The tool that we used allows for the analysis of microorganisms and enzymes within the gut microbiota. It achieves this by initially clustering enzymes based on their correlations with species and subsequently utilizing these clustering results to evaluate the ability of groups to differentiate between patient and healthy cohorts. By integrating species and enzymes, it is possible to identify pathogen microorganisms and enzyme clusters, that have the potential to distinguish cases (individuals with CRC) from controls (healthy individuals). The identified enzyme clusters and associated species could potentially act as biomarkers for colorectal cancer (CRC), enabling early diagnosis and more effective treatment. This approach holds promise for further exploration of the gut microbiota and its importance in human health and illness. Keywords: Bioinformatics, Machine Learning, Colorectal Cancer DiagnosisMaster Thesis Meme Kanseri Histopatoloji Görüntülerinde Evrişimsel Sinir Ağları Kullanarak Tümör Tespiti(Abdullah Gül Üniversitesi, Fen Bilimleri Enstitüsü, 2024) Şahbaz, Zeki; Aksebzeci, Bekir HakanBreast cancer is one of the most common cancer types among women worldwide. Early detection significantly increases the chances of survival and effective treatment, making advancements in diagnostic methodologies crucial. This study aims to improve the detection of tumor cells in breast cancer histopathology images using deep learning and image processing techniques. Significant modifications have been made to the hyperparameters, including the tumor bounding box size, batch size, optimization algorithms, learning rate, and weight decay. These changes focus on determining the best parameters of the Faster R-CNN model. A comprehensive analysis of different parameters was conducted using the Breast Cancer Histopathological Annotation and Diagnosis (BreCaHAD) dataset. The analysis identified the best settings for model performance, shows by improvements in precision, recall, and F-score. Our research contributes to the field of medical image analysis by identifying critical factors that affect the accuracy of tumor detection, contributing to the development of more accurate diagnostic tools.Master Thesis Yarı-Tek-Aşamalı Dört-Anahtarlı Alçaltıcı-Yükseltici Evirici için Pürüzsüz Mod Geçiş Tekniğinin İncelenmesi ve Geliştirilmesi(Abdullah Gül Üniversitesi, Fen Bilimleri Enstitüsü, 2023) Keskinkılıç, Ebubekir; Keskinkılıç, Ebubekir; Tekgün, BurakIn recent decades, given the world's inevitable energy scarcity, increasing energy demand and green energy concerns, high efficiency energy conversion has become more important and attractive than ever, and researchers have directed their interest to energy-efficient converters. Inverters are a commonly utilized type of converter, which can be classified into two categories: single and two-stage inverters. Considering the inherent drawbacks of traditional inverters, a quasi-single-stage inverter (QSSI) has emerged. The QSSI uses a DC-DC converter to shape the rectified version of the desired AC waveform in the first stage and, in the second stage, it switches only once to alternate the polarity. It stands forward in terms of efficiency, control simplicity, and system stability. Among QSSI, a non-inverting buck-boost converter has drawn attention due to its capability to perform both step-up and down modes and its bidirectional power transfer feature. In the first stage of the QSS non-inverting buck-boost converter; smooth transitions between the buck and boost modes and efficient conversion cannot be achieved by the traditional two-mode control method when the output voltage level is close to the input voltage level due to various limitations, non-idealities, and disturbances. Many methods have been applied and studied in the literature to minimize or eliminate the effects of the region which is called the 'dead zone'. In this thesis study, further efficiency and THD improvement for the QSSI is targeted by employing a four-mode control method. The study incorporates a comparative study of the dead zone effects on inverter systems, which have not been previously documented in the literature. Moreover, it places a priority on optimizing efficiency and minimizing distortion in various applications—ranging from motor control and solar energy systems to grid-tied wind turbines and switched-mode power supplies—by comparing existing methods with open-loop voltage control. In conclusion, the theoretical results are verified with experimental studies.Master Thesis Derin Öğrenme Yöntemleri Kullanarak Dermatoskopik Görüntülerden Otomatik Cilt Kanseri Tespiti ve Sınıflandırılması(Abdullah Gül Üniversitesi / Fen Bilimleri Enstitüsü, 2023) Kalaycı, Serdar; Yılmaz, BülentEarly detection of skin cancer is crucial for successful treatment and improved patient outcomes. The most prevalent form of cancer is skin cancer and if left undetected, it can spread and become more difficult to treat. A dangerous and frequently fatal type of skin cancer is melanoma. Regular skin examinations and self-examinations can help identify suspicious moles or lesions, which can then be evaluated by a dermatologist. In addition, advances in technology and artificial intelligence have enabled the development of tools for automated skin cancer screening, providing a convenient and efficient means of early detection. This can lead to more efficient diagnosis, reduced healthcare costs and improved patient care. By evaluating skin lesions from images, deep learning techniques have shown considerable potential in increasing the precision of melanoma detection. By using large datasets and complex neural networks, deep learning algorithms can effectively distinguish between benign and malignant skin lesions with high accuracy. Ensemble of CNN models helps improve the performance and reliability of the classification task. By combining the predictions of multiple CNN models lead to more accurate and robust predictions. In this thesis, for melanoma classification problem, many different data augmentations techniques applied and different convolutional neural networks architectures evaluated, applied vignetting effect filter and hair noise in accordance with the dataset and results of ensemble of the best CNN models are promising. This thesis attempts to produce a reliable model for the classification of melanoma by conducting experiments on two combined publically accessible data sets, ISIC 2019 and ISIC 2020. On the testing sets in our studies, the proposed solution attained 95.75% AUC.Master Thesis Anahtarlamalı Relüktans Motorlarında Tork Dalgalanmasının Azaltılması için Uyarlanabilir Çevrimiçi Tork Paylaşım Fonksiyonu Geliştirilmesi(Abdullah Gül Üniversitesi, Fen Bilimleri Enstitüsü, 2023) Genç, Ufuk; Tekgün, BurakElectrical machines play a crucial role in modern society by transforming electrical energy into mechanical energy and vice versa. These machines include various types of motors and generators, which are used in a wide range of applications such as electric vehicles, industrial automation, and renewable energy systems. One of the popular electrical machines is the switched reluctance machine (SRM), which is known for its high reliability and efficiency. The key advantages of the SRM include its simple structure, robustness, and low cost. The SRM does not require a permanent magnet or an excitation winding, making it an attractive option for high-volume, low-cost applications. Despite its advantages, the SRM also has some disadvantages that need to be considered. One of the main drawbacks of the SRM is being susceptible to torque ripple, which can result in vibration and noise. In order to overcome these disadvantages, advanced control methods have been developed for the SRM. One such control method is the torque sharing function, which distributes the load among the phases of the motor. This results in improved torque characteristics and reduced torque ripple. However, this control method also has some disadvantages, such as increased complexity and the need for more advanced sensors and controllers. Additionally, the torque sharing function may result in reduced efficiency, especially at high speeds. The purpose of this thesis study is to improve the torque ripple performance of SRM for a wide speed range through the proposed control approach. In conclusion, minimizing the torque ripple is a critical aspect of the operation of SRMs, and a range of control strategies and techniques can be used to achieve this goal. By reducing the torque ripple, SRMs can deliver improved efficiency, performance, and reliability, making them even more attractive for a wide range of applications.Master Thesis Bilgisayar Algoritmalarının GPU ile Hızlandırılması(Abdullah Gül Üniversitesi, Fen Bilimleri Enstitüsü, 2023) Yalçın, Salih; Alkan, Gülay YalçınTravelling Salesman Problem (TSP) is one of the significant problems in computer science which tries to find the shortest path for a salesman who needs to visit a set of cities and it involves in many computing problems such as networks, genome analysis, logistic etc. Using parallel executing paradigms, especially GPUs, is appealing in order to reduce the problem-solving time of TSP. One of the main issues in GPUs is to have limited GPU memory which would not be enough for the entire data. Therefore, transferring data from host device would reduce the performance in execution time. In this study, we present a methodology for compressing data to represent cities in the TSP so that we include more cities in GPU memory. We implement our methodology in Iterated Local Search (ILS) algorithm with 2-opt and show that our implementation presents 29% performance improvement compared to the state-of-the-art GPU implementation.Master Thesis Erken Orman Yangını Tespiti için Otonom Heterojen Çoklu Robot Sistemi Tasarımı(Abdullah Gül Üniversitesi, Fen Bilimleri Enstitüsü, 2022) Serin, Ömer Faruk; Güler, SametThe usage of autonomous multi-robot systems for human life-endangering applications is emerging. Early wildfire detection and firefighting are two example applications. In this study, a heterogenous multi-robot system is proposed for both fire detection and response. The system employs an unmanned aerial vehicle for beyond-visual line-of-sight observations and an unmanned ground robot for fire extinguisher carrying. The proposed method uses ultrawideband (UWB) communication and ranging modules for the relative localization of robots during their movements. A specially trained YOLOv7 object detection model is used for robustly detecting forest fires and smoke while a modified version of the Vector Field Histogram Plus (VFH+) algorithm on the ground robot is used for obstacle avoidance while navigating. The structural design of the system requires no odometry or mapping of the environment hence improving the applicability of the system while decreasing system complexity. Additionally, the proposed UWB localization system is shown to be robust in long-lasting operations unlike many odometry-based approaches which accumulate errors with time. Moreover, localization of the UAV is realized with only three independent UWB-based range measurements and the altitude information of the UAV. The system is tested both in a realistic simulation environment and in real experimental setups with multiple runs. Results showed that the proposed system is improvable for better detection and practical to implement even in a dense forest environment without the need for GPS sensors, odometer data, or magnetometer.Master Thesis Kanser Alt Tipi Tanımlama Problemi için Bir Etiket Yayma Yaklaşımı Geliştirme(Tubitak Scientific & Technological Research Council Turkey, 2022) Guner, Pinar; Bakir-Gungor, Burcu; Coskun, Mustafa; Güner, Pınar; Güngör, Burcu; Coşkun, MustafaKanser terimi, anormal hücrelerin kontrolden çıkıp diğer dokuları istila ettiği hastalıkları tanımlamak için kullanılır. Çok sayıda kanser türü vardır ve birçok kanser türü, farklı klinik ve biyolojik etkileri olan çeşitli alt tiplere sahiptir. Bu farklılıklar, kanserin farklı alt tiplerinin tedavisi için farklı yöntemlerin izlenmesi gerektiğini göstermektedir. Kişiselleştirilmiş tıbbın geliştirilmesine yardımcı olabileceğinden, kanser alt tiplerini keşfetmek biyoinformatikte önemli bir problemdir. Kanserin alt tipinin bilinmesi, tedavi basamaklarının ve öngörünün belirlenmesinde faydalıdır. Hesaplamalı biyoinformatik yöntemler, farklı kanser alt tiplerinin ortak moleküler patolojisini ortaya çıkararak hedeflenen tedavileri tasarlamak için kanser analizi yapmaya yardımcı olur. Şimdiye kadar, kanser alt tiplerini keşfetmek veya kanseri bilgilendirici alt tiplere ayırmak için çeşitli hesaplamalı yöntemler önerildi. Ancak, mevcut çalışmalar verilerin seyrekliğini dikkate almamakta ve kötü koşullu (tersi alınamayan) çözümle sonuçlanmaktadır. Bu eksikliği gidermek için, bu tezde, uygulamalı sayısal cebir tekniklerini kullanarak kanseri alt tiplerine ayırmak için alternatif bir denetimsiz hesaplama yöntemi öneriyoruz. Daha detaylı olarak, bu etiket yayma tabanlı yaklaşımı kolon, baş ve boyun, rahim, mesane ve meme tümörlerinin somatik mutasyon profillerini sınıflandırmak için uyguladık. Sonra, yöntemimizin performansını temel yöntemlerle karşılaştırarak değerlendirdik. Kapsamlı deneyler, yaklaşımımızın, modern denetimsiz ve denetimli yaklaşımlardan büyük ölçüde daha iyi performans göstererek tümör sınıflandırma görevlerini yüksek oranda yerine getirdiğini kanıtlamaktadır.Master Thesis Grafik Teorisi Tabanlı Trafik Işığı Yöntemi(Abdullah Gül Üniversitesi, Fen Bilimleri Enstitüsü, 2022) Thahir, Adam Rizvi; Güngör, Vehbi Çağrı; Coşkun, MustafaTraffic congestion and delays caused in traffic light intersections can adversely affect countries in terms of money, time, and air pollution. With the advancement of computational power as well as artificial intelligent algorithms, researchers seek novel and optimized solutions to the traffic congestion problem. Most modern traffic light systems use manually designed traffic phase plans at intersections, and although this has proven to be relatively sufficient for today's traffic management systems, implementing a smarter traffic phase selection system is deemed to be more effective. Traditional approaches rely heavily on traffic history (static information), whereas Reinforcement Learning (RL) algorithms, which offer an 'adoptable'/dynamic traffic management system, are gaining increased research interest. Despite the usefulness of these RL based deep learning techniques, they inherently suffer from training time to apply them in real-world traffic management systems. This study aims to alleviate the training time problem of deep learning-based techniques, The research brings forth a novel graph-based approach that is able to use known occupancies of roads to predict which other roads in a given network would become congested in the future. Based on the predictions obtained, we are able to dynamically set traffic light times in all intersections within a connected network, starting from roads with known occupancies, and moving along connected roads that are anticipated to be congested. Predications are done using edge-based semi-supervised graph algorithms. Conducted simulations show that our approach can yield comparable average wait time to that of deep-learning based approach in minutes, compared to the much longer training time required by the deep-learning models. Keywords: Deep Learning, Reinforcement Learning, Traffic Flow, CongestionMaster Thesis Esnek Kağıt Tabanlı Kapasitif Sensör Kullanarak Solunum İzleme(Abdullah Gül Üniversitesi, Fen Bilimleri Enstitüsü, 2022) Solak, İrfan; İçöz, Kutay; Hah, DooyoungRespiration is an action known to be essential and crucial for life. Unfortunately, in some cases such as illnesses and accidents various respiratory problems can be experienced. It might be difficult to maintain normal respiration for the people who have respiratory diseases. It is known that respiration monitoring of people who have respiratory problems, albeit for different reasons, is important in terms of their treatment and maintaining their life quality. Current respiration monitoring systems are expensive and bulky. Many of these systems are only available at hospitals or in laboratories. Low-cost, easy to use and portable respiratory monitoring devices are needed. Having these motivations, we aimed to monitor respiration by designing and producing a paper-based sensor that is easy to manufacture, low-cost, and highly responsive. The sensor, which is the subject of this thesis project, has potential to be used for different purposes such as measuring the humidity in the environment. In this project, we focused on designing a system for people who have respiratory problems by providing respiration monitoring data. In addition, according to the data obtained, we are able to analyze the health status of the users. Therefore, this sensor can be used both for the detection of respiration diseases and monitor the status of the patients. In this way, respiration related unhealthy situation can be detected and treated immediately.