Scopus İndeksli Yayınlar Koleksiyonu
Permanent URI for this collectionhttps://hdl.handle.net/20.500.12573/395
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Article Citation - WoS: 7Citation - Scopus: 8The Determination of Distinctive Single Nucleotide Polymorphism Sets for the Diagnosis of Behcet's Disease(IEEE Computer Soc, 2022-05-01) Isik, Yunus Emre; Gormez, Yasin; Aydin, Zafer; Bakir-Gungor, BurcuBehcet's Disease (BD) is a multi-system inflammatory disorder in which the etiology remains unclear. The most probable hypothesis is that genetic tendency and environmental factors play roles in the development of BD. In order to find the essential reasons, genetic changes on thousands of genes should be analyzed. Besides, there is a need for extra analysis to find out which genetic factor affects the disease. Machine learning approaches have high potential for extracting the knowledge from genomics and selecting the representative Single Nucleotide Polymorphisms (SNPs) as the most effective features for the clinical diagnosis process. In this study, we have attempted to identify representative SNPs using feature selection methods, incorporating biological information and aimed to develop a machine-learning model for diagnosing Behcet's disease. By combining biological information and machine learning classifiers, up to 99.64 percent accuracy of disease prediction is achieved using only 13,611 out of 311,459 SNPs. In addition, we revealed the SNPs that are most distinctive by performing repeated feature selection in cross-validation experiments.Article Citation - WoS: 4Citation - Scopus: 7IGPRED-Multitask: A Deep Learning Model to Predict Protein Secondary Structure, Torsion Angles and Solvent Accessibility(IEEE Computer Soc, 2023-03-01) Gormez, Yasin; Aydin, ZaferProtein secondary structure, solvent accessibility and torsion angle predictions are preliminary steps to predict 3D structure of a protein. Deep learning approaches have achieved significant improvements in predicting various features of protein structure. In this study, IGPRED-Multitask, a deep learning model with multi task learning architecture based on deep inception network, graph convolutional network and a bidirectional long short-term memory is proposed. Moreover, hyper-parameters of the model are fine-tuned using Bayesian optimization, which is faster and more effective than grid search. The same benchmark test data sets as in the OPUS-TASS paper including TEST2016, TEST2018, CASP12, CASP13, CASPFM, HARD68, CAMEO93, CAMEO93_HARD, as well as the train and validation sets, are used for fair comparison with the literature. Statistically significant improvements are observed in secondary structure prediction on 4 datasets, in phi angle prediction on 2 datasets and in psi angel prediction on 3 datasets compared to the state-of-the-art methods. For solvent accessibility prediction, TEST2016 and TEST2018 datasets are used only to assess the performance of the proposed model.Article Citation - WoS: 26Citation - Scopus: 27ATOM: AI-Powered Sustainable Resource Management for Serverless Edge Computing Environments(IEEE-Inst Electrical Electronics Engineers Inc, 2024-11) Golec, Muhammed; Gill, Sukhpal Singh; Cuadrado, Felix; Parlikad, Ajith Kumar; Xu, Minxian; Wu, Huaming; Uhlig, SteveServerless edge computing decreases unnecessary resource usage on end devices with limited processing power and storage capacity. Despite its benefits, serverless edge computing's zero scalability is the major source of the cold start delay, which is yet unsolved. This latency is unacceptable for time-sensitive Internet of Things (IoT) applications like autonomous cars. Most existing approaches need containers to idle and use extra computing resources. Edge devices have fewer resources than cloud-based systems, requiring new sustainable solutions. Therefore, we propose an AI-powered, sustainable resource management framework called ATOM for serverless edge computing. ATOM utilizes a deep reinforcement learning model to predict exactly when cold start latency will happen. We create a cold start dataset using a heart disease risk scenario and deploy using Google Cloud Functions. To demonstrate the superiority of ATOM, its performance is compared with two different baselines, which use the warm-start containers and a two-layer adaptive approach. The experimental results showed that although the ATOM required more calculation time of 118.76 seconds, it performed better in predicting cold start than baseline models with an RMSE ratio of 148.76. Additionally, the energy consumption and CO2 emission amount of these models are evaluated and compared for the training and prediction phases.