Scopus İndeksli Yayınlar Koleksiyonu
Permanent URI for this collectionhttps://hdl.handle.net/20.500.12573/395
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Conference Object Normal Mixture Model-Based Clustering of Data Using Genetic Algorithm(Springer International Publishing AG, 2020) Gogebakan, Maruf; Erol, HamzaIn this study, a new algorithm was developed for clustering multivariate big data. Normal mixture distributions are used to determine the partitions of variables. Normal mixture models obtained from the partitions of variables are generated using Genetic Algorithms (GA). Each partition in the variables corresponds to a clustering center in the normal mixture model. The best model that fits the data structure from normal mixture models is obtained by using the information criteria obtained from normal mixture distributions.Conference Object Protein-Protein Etkilesim Ağlarinda Aktif Alt Ağ Arama Yöntemlerinin Performans Degerlendirmeleri(Institute of Electrical and Electronics Engineers Inc., 2019-09) Güner, Pinar; Bakir-Güngör, BurcuProtein-protein interaction networks are mathematical representations of the physical contacts between proteins in the cell. A group of interconnected proteins in a protein-protein interaction network that contains most of the disease associated proteins and some interacting other proteins is called an active subnetwork. Active subnetwork search is important to understand mechanisms underlying diseases. Active subnetworks are used to discover disease related regulatory pathways, functional modules and to classify diseases. In the literature there are many methods to search for active subnetworks. The purpose of this study is to compare the performance of different subnetwork identification methods. By using the Rheumatoid Arthritis dataset, the performances of greedy approach, genetic algorithm, simulated annealing algorithm, prize collecting steiner forest and game theory based subnetwork search methods are compared. © 2020 Elsevier B.V., All rights reserved.