Scopus İndeksli Yayınlar Koleksiyonu
Permanent URI for this collectionhttps://hdl.handle.net/20.500.12573/395
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Conference Object The Effect of Different Classifiers on Recursive Cluster Elimination in the Analysis of Transcriptomic Data(Institute of Electrical and Electronics Engineers Inc., 2023-10-11) Bulut, Nurten; Bakir-Güngör, Burcu; Qaqish, Bahjat F.; Yousef, MalikGene expression data with limited sample size and a large number of genes are frequently encountered in genetic studies. In such high-dimensional data, identification of genes that distinguish between disease states is a challenging task. Feature selection (FS) is a useful approach in dealing with high dimensionality. Support Vector Machines Recursive Cluster Elimination (SVM-RCE) is a technique for FS in high-dimensional data. The SVM-RCE approach has been utilized for identification of clusters of genes whose expression levels correlate with pathological state. A key step in SVM-RCE is the use of an SVM classifier to assign an area under the curve (AUC) score to each gene cluster based on its ability to predict class labels. In this study, we investigate the use of alternative classifiers in the cluster-scoring step. Specifically, we compare Support Vector Machines, Random Forest, XgBoost, Naive Bayes, and linear logistic regression. In addition to AUC score performance evaluation, the algorithms are compared in terms of the number of selected genes at different levels of clustering and in terms of the running time. © 2023 Elsevier B.V., All rights reserved.Conference Object Citation - Scopus: 4A Model Selection Algorithm for Mixture Model Clustering of Heterogeneous Multivariate Data(IEEE, 2013-06) Erol, H.A model selection algorithm is developed for finding the best model among a set of mixture of normal densities fitted to heterogeneous multivariate data. Model selection algorithm proposed first finds total number of mixture of normal densities then selects possible number of mixture of normal densities and finally searches the best model among them in mixture model clustering of heterogeneous multivariate data. Log-likelihood function, Akaike's information criteria and Bayesian information criteria values are computed and graphically ploted for each mixture of normal densities. The best model is chosen according to the values of these information criterions. © 2013 IEEE. © 2013 Elsevier B.V., All rights reserved.