Scopus İndeksli Yayınlar Koleksiyonu

Permanent URI for this collectionhttps://hdl.handle.net/20.500.12573/395

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  • Article
    Citation - Scopus: 25
    Recursive Cluster Elimination Based Rank Function (SVM-RCE-R) Implemented in KNIME
    (F1000 Research Ltd, 2021-01-05) Yousef, Malik; Bakir-Güngör, Burcu; Jabeer, Amhar; Göy, Gökhan; Qureshi, Rehman A.; C Showe, Louise; C. Showe, Louise
    In our earlier study, we proposed a novel feature selection approach, Recursive Cluster Elimination with Support Vector Machines (SVM-RCE) and implemented this approach in Matlab. Interest in this approach has grown over time and several researchers have incorporated SVM-RCE into their studies, resulting in a substantial number of scientific publications. This increased interest encouraged us to reconsider how feature selection, particularly in biological datasets, can benefit from considering the relationships of those genes in the selection process, this led to our development of SVM-RCE-R. SVM-RCE-R, further enhances the capabilities of SVM-RCE by the addition of a novel user specified ranking function. This ranking function enables the user to stipulate the weights of the accuracy, sensitivity, specificity, f-measure, area under the curve and the precision in the ranking function This flexibility allows the user to select for greater sensitivity or greater specificity as needed for a specific project. The usefulness of SVM-RCE-R is further supported by development of the maTE tool which uses a similar approach to identify MicroRNA (miRNA) targets. We have also now implemented the SVM-RCE-R algorithm in Knime in order to make it easier to applyThe use of SVM-RCE-R in Knime is simple and intuitive and allows researchers to immediately begin their analysis without having to consult an information technology specialist. The input for the Knime implemented tool is an EXCEL file (or text or CSV) with a simple structure and the output is also an EXCEL file. The Knime version also incorporates new features not available in SVM-RCE. The results show that the inclusion of the ranking function has a significant impact on the performance of SVM-RCE-R. Some of the clusters that achieve high scores for a specified ranking can also have high scores in other metrics. © 2021 Elsevier B.V., All rights reserved.
  • Article
    Citation - Scopus: 5
    Hyperplastic and Tubular Polyp Classification Using Machine Learning and Feature Selection
    (Elsevier B.V., 2024) Doǧan, Refika Sultan; Akay, Ebru; Doǧan, Serkan; Yilmaz, Bulent
    Purpose: The aim of this study is to develop an effective approach for differentiating between hyperplastic and tubular adenoma colon polyps, which is one of the most difficult tasks in colonoscopy procedures. The main research challenge is how to improve the classification of these polyp subtypes applying various focusing levels on the polyp images, data preprocessing approaches, and classification algorithms. Methods: This study employed 202 colonoscopy videos from a total of 201 patients, focusing on 59 videos containing hyperplastic and tubular adenoma polyps. Manually extract key frames and several feature extraction and classification techniques were applied. The influence of different datasets with various focuses as well as data preprocessing steps on the performance of classification was examined, and AUC values were calculated using ten classifiers. Results: The study discovered that the optimal dataset, data preprocessing method, and classification algorithm all had significant effects on classification results. The Random Forest model with the Recursive Feature Elimination (RFE) feature selection approach, for example, consistently outperformed other models and achieved the highest AUC value of 0.9067. In terms of accuracy, F1 score, recall, and AUC, the suggested model outperformed a gastroenterologist, nevertheless precision remained slightly lower. Conclusion: This study emphasizes the importance of dataset selection, data preprocessing, and feature selection in enhancing the classification of difficult colon polyp subtypes. The suggested model offers a promising model for the clinical differentiation of hyperplastic and tubular adenoma polyps, potentially improving diagnostic accuracy in gastroenterology. © 2024 Elsevier B.V., All rights reserved.