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Scopus İndeksli Yayınlar Koleksiyonu

Permanent URI for this collectionhttps://hdl.handle.net/20.500.12573/395

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Scopus Q: search.filters.scopusQuartile.Q2Subject: search.filters.subject.Computational Modeling

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  • Article
    Citation - WoS: 5
    Citation - Scopus: 5
    Novel Antimicrobial Peptide Design Using Motif Match Score Representation
    (IEEE Computer Soc, 2024-11) Soylemez, Ummu Gulsum; Yousef, Malik; Kesmen, Zulal; Bakir-Gungor, Burcu
    Antimicrobial peptides (AMPs) have drawn the interest of the researchers since they offer an alternative to the traditional antibiotics in the fight against antibiotic resistance and they exhibit additional pharmaceutically significant properties. Recently, computational approaches attemp to reveal how antibacterial activity is determined from a machine learning perspective and they aim to search and find the biological cues or characteristics that control antimicrobial activity via incorporating motif match scores. This study is dedicated to the development of a machine learning framework aimed at devising novel antimicrobial peptide (AMP) sequences potentially effective against Gram-positive/Gram-negative bacteria. In order to design newly generated sequences classified as either AMP or non-AMP, various classification models were trained. These novel sequences underwent validation utilizing the "DBAASP: strain-specific antibacterial prediction based on machine learning approaches and data on AMP sequences" tool. The findings presented herein represent a significant stride in this computational research, streamlining the process of AMP creation or modification within wet lab environments.
  • Article
    Citation - WoS: 26
    Citation - Scopus: 27
    ATOM: AI-Powered Sustainable Resource Management for Serverless Edge Computing Environments
    (IEEE-Inst Electrical Electronics Engineers Inc, 2024-11) Golec, Muhammed; Gill, Sukhpal Singh; Cuadrado, Felix; Parlikad, Ajith Kumar; Xu, Minxian; Wu, Huaming; Uhlig, Steve
    Serverless edge computing decreases unnecessary resource usage on end devices with limited processing power and storage capacity. Despite its benefits, serverless edge computing's zero scalability is the major source of the cold start delay, which is yet unsolved. This latency is unacceptable for time-sensitive Internet of Things (IoT) applications like autonomous cars. Most existing approaches need containers to idle and use extra computing resources. Edge devices have fewer resources than cloud-based systems, requiring new sustainable solutions. Therefore, we propose an AI-powered, sustainable resource management framework called ATOM for serverless edge computing. ATOM utilizes a deep reinforcement learning model to predict exactly when cold start latency will happen. We create a cold start dataset using a heart disease risk scenario and deploy using Google Cloud Functions. To demonstrate the superiority of ATOM, its performance is compared with two different baselines, which use the warm-start containers and a two-layer adaptive approach. The experimental results showed that although the ATOM required more calculation time of 118.76 seconds, it performed better in predicting cold start than baseline models with an RMSE ratio of 148.76. Additionally, the energy consumption and CO2 emission amount of these models are evaluated and compared for the training and prediction phases.