Scopus İndeksli Yayınlar Koleksiyonu
Permanent URI for this collectionhttps://hdl.handle.net/20.500.12573/395
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Article Time Distributed Classification of Alzheimer’s Disease on MRI Scans(John Wiley and Sons Ltd, 2026) Dundar, Mehmet Sait; Yilmaz, BulentThe diagnosis of Alzheimer's disease (AD) has progressively depended on sophisticated neuroimaging methods alongside cognitive assessments. This study combines volumetric feature analysis with computational modeling techniques, focusing on spatial and temporal analysis, to categorize individuals as cognitively normal (CN), mild cognitive impairment (MCI), or AD using magnetic resonance imaging (MRI) data. In the initial phase, volumetric changes, comprising cortical thickness, white matter, grey matter, cerebrospinal fluid, and total intracranial volume, were derived from the Alzheimer's Disease Neuroimaging Initiative (ADNI) dataset utilizing the CAT12 toolbox in statistical parametric mapping (SPM). Linear regression was utilized on these variables over time to create slopes that reflect volumetric change rates, which then served as inputs for machine learning classifiers. The slopes of cortical thickness exhibited the greatest classification accuracy, reaching 82.5% with a random forest model for differentiating AD from CN individuals. During the second phase, a deep learning methodology was utilized, relying solely on the MRI scans and excluding the outcomes from the first phase. A pre-trained 3D ResNet-101 convolutional neural network (CNN) model extracted spatial characteristics from MRI volumes, whereas long short-term memory (LSTM) networks recorded temporal dynamics across subsequent annual scans. This hybrid CNN-LSTM design markedly improved classification performance, attaining 96.7% accuracy for AD against CN and enhancing the distinction of MCI cases. Nonetheless, discrepancies in MCI categorization were chiefly ascribed to the restricted access to annual MRI data and the model's pre-training on CN and AD cohorts. These findings highlight the potential of integrating volumetric statistical analysis with deep learning for automated AD categorization. This work enhances neuroimaging diagnostic methods by utilizing both spatial and temporal MRI data, enabling early diagnosis and better evaluation of disease development.Article Machine Learning and Scenario-Based Forecasting of Türkiye’s Renewable Energy Transition toward Net-Zero 2053(Elsevier Ltd, 2026-05) Sutcu, Muhammed; Yildiz, Baris; Sahin, Nurettin; Almomany, Abedalmuhdi; Gulbahar, Ibrahim TumayThe issue of global warming has been identified as one of the most critical challenges of the 21st century, with the consumption of fossil fuels being identified as a major contributor to greenhouse gas emissions. In response to these challenges, countries worldwide are expediting their transition towards renewable energy sources to meet international climate commitments, such as the Paris Agreement, and to achieve long-term sustainability goals. Türkiye has established a target to achieve net-zero emissions by 2053. This objective is consistent with both the nation's domestic energy strategy and its international commitments. Nevertheless, the transition from fossil fuels to renewable energy sources is impeded by geographical, economic, and technological constraints. The present study aims to assess the capacity and efficiency of renewable energy in Türkiye with environmental protocols and future electricity demand projections. Electricity generation, transmission data, and national energy plans are used to identify future electricity generation and capacity trends. In the context of this study, a range of machine learning models is executed across diverse scenarios, yielding a series of outcomes. Consequently, the repercussions of regulatory measures and financial investments were examined, and prospective inferences were derived. The findings underscore the pivotal role of scenario-based modeling in formulating sustainable energy policies and directing investment decisions within the context of climate change mitigation.Article Citation - WoS: 1Citation - Scopus: 1Machine Learning for V2X-Enabled Microgrids: A Bibliometric and Thematic Review of Intelligent Energy Management Applications(Springer Heidelberg, 2026-03-09) Dogan, Yasemin; Unlu, RamazanModern power systems are evolving due to convergence of electric mobility, artificial intelligence, and renewable energy integration. Electric vehicles serve as dynamic, mobile energy storage units playing a vital role in ensuring resilient microgrid operations, via vehicle-to-everything (V2X) technology. However, despite the rise of machine learning (ML) in energy management, much of the existing literature remains fragmented lacking a holistic perspective across all facets of V2X-enabled microgrids. This study fills this gap by conducting a systematic bibliometric and thematic analysis of 310 articles obtained from Web of Science (2013-2024). By combining bibliometric mapping with thematic synthesis, the research identifies dominant and emerging ML techniques-ranging from reinforcement learning to federated learning-and evaluates their roles in microgrid management. The study highlights underexplored areas, including decentralized coordination, encouraging prosumer participation, understanding user behavior, safeguarding cybersecurity, improving real-time optimization, and the effective integration and adaptation of V2X technology within microgrid ecosystems. These gaps emphasize the need for interdisciplinary research and policy frameworks to address the social dimensions of future energy systems. Beyond a comprehensive overview, this paper proposes a research roadmap integrating technical, social, and policy dimensions. It offers actionable guidance for researchers, stakeholders aiming to unlock the potential of intelligent, human-centered, and socially inclusive energy ecosystems. Furthermore, the findings align with UN Sustainable Development Goals (SDG 7, 11, and 13), while also creating a positive impact on humanity by supporting the well-being of both society and the planet. Ultimately, this reinforces the indispensable role of ML in advancing the zero-carbon transition.Article Citation - WoS: 2Citation - Scopus: 1A Comprehensive Analysis of Acoustic Emission Signals To Distinguish the Different Damage Types for Fiber-Reinforced Polymers: A Review(Wiley, 2025-12-03) Yilmaz, CagatayFiber-reinforced polymers (FRP) attract the attention of key industries, such as aerospace, wind energy, and automotive, as they can reduce the weight of structural components without compromising their mechanical properties. Due to FRP's anisotropic and non-homogeneous structure, their failure under different loading conditions and the corresponding failure mechanisms must be investigated. One method that progressively monitors the failure of FRP underload is Acoustic Emission (AE). AE can register the elastic stress waves in the form of digitized waveforms, released by the discontinuous events that occur in the FRP under load. These discontinuities can be clustered and identified as transverse cracking, fiber/matrix interface debonding, delamination, and fiber failure by analyzing the AE waveforms. Recently, numerous clustering approaches using machine learning algorithms, along with the varying features of AE waveforms, have been developed and are being used. These algorithms include supervised and unsupervised clustering, deep learning algorithms, and neural network methods, among others. While supervised algorithms require a training dataset to classify AE signals, unsupervised algorithms can perform clustering without training datasets. Deep learning and neural network algorithms can train themselves to cluster data, but they may require a significant amount of computer power when the dataset is large. This review paper provides comprehensive information on the clustering algorithm, along with the AE wave features, the range of features for different damage types, and the type of reinforcer.Article Citation - WoS: 85Citation - Scopus: 102Statistical and Machine Learning Techniques in Human Microbiome Studies: Contemporary Challenges and Solutions(Frontiers Media S.A., 2021-02-22) Moreno-Indias, Isabel; Lahti, Leo; Nedyalkova, Miroslava; Elbere, Ilze; Roshchupkin, Gennady; Adilovic, Muhamed; Claesson, Marcus J.The human microbiome has emerged as a central research topic in human biology and biomedicine. Current microbiome studies generate high-throughput omics data across different body sites, populations, and life stages. Many of the challenges in microbiome research are similar to other high-throughput studies, the quantitative analyses need to address the heterogeneity of data, specific statistical properties, and the remarkable variation in microbiome composition across individuals and body sites. This has led to a broad spectrum of statistical and machine learning challenges that range from study design, data processing, and standardization to analysis, modeling, cross-study comparison, prediction, data science ecosystems, and reproducible reporting. Nevertheless, although many statistics and machine learning approaches and tools have been developed, new techniques are needed to deal with emerging applications and the vast heterogeneity of microbiome data. We review and discuss emerging applications of statistical and machine learning techniques in human microbiome studies and introduce the COST Action CA18131 "ML4Microbiome" that brings together microbiome researchers and machine learning experts to address current challenges such as standardization of analysis pipelines for reproducibility of data analysis results, benchmarking, improvement, or development of existing and new tools and ontologies.Article Citation - WoS: 24Citation - Scopus: 32Recent Advances in Machine Learning for Network Automation in the O-RAN(MDPI, 2023-10-28) Hamdan, Mutasem Q.; Lee, Haeyoung; Triantafyllopoulou, Dionysia; Borralho, Ruben; Kose, Abdulkadir; Amiri, Esmaeil; Tafazolli, RahimThe evolution of network technologies has witnessed a paradigm shift toward open and intelligent networks, with the Open Radio Access Network (O-RAN) architecture emerging as a promising solution. O-RAN introduces disaggregation and virtualization, enabling network operators to deploy multi-vendor and interoperable solutions. However, managing and automating the complex O-RAN ecosystem presents numerous challenges. To address this, machine learning (ML) techniques have gained considerable attention in recent years, offering promising avenues for network automation in O-RAN. This paper presents a comprehensive survey of the current research efforts on network automation usingML in O-RAN.We begin by providing an overview of the O-RAN architecture and its key components, highlighting the need for automation. Subsequently, we delve into O-RAN support forML techniques. The survey then explores challenges in network automation usingML within the O-RAN environment, followed by the existing research studies discussing application of ML algorithms and frameworks for network automation in O-RAN. The survey further discusses the research opportunities by identifying important aspects whereML techniques can benefit.Article Citation - Scopus: 3Prediction of Colorectal Cancer Based on Taxonomic Levels of Microorganisms and Discovery of Taxonomic Biomarkers Using the Grouping-Scoring (G-S-M) Approach(Elsevier Ltd, 2025-03) Bakir-Güngör, Burcu; Temiz, Mustafa; Canakcimaksutoglu, Beyza; Yousef, MalikColorectal cancer (CRC) is one of the most prevalent forms of cancer globally. The human gut microbiome plays an important role in the development of CRC and serves as a biomarker for early detection and treatment. This research effort focuses on the identification of potential taxonomic biomarkers of CRC using a grouping-based feature selection method. Additionally, this study investigates the effect of incorporating biological domain knowledge into the feature selection process while identifying CRC-associated microorganisms. Conventional feature selection techniques often fail to leverage existing biological knowledge during metagenomic data analysis. To address this gap, we propose taxonomy-based Grouping Scoring Modeling (G-S-M) method that integrates biological domain knowledge into feature grouping and selection. In this study, using metagenomic data related to CRC, classification is performed at three taxonomic levels (genus, family and order). The MetaPhlAn tool is employed to determine the relative abundance values of species in each sample. Comparative performance analyses involve six feature selection methods and four classification algorithms. When experimented on two CRC associated metagenomics datasets, the highest performance metric, yielding an AUC of 0.90, is observed at the genus taxonomic level. At this level, 7 out of top 10 groups (Parvimonas, Peptostreptococcus, Fusobacterium, Gemella, Streptococcus, Porphyromonas and Solobacterium) were commonly identified for both datasets. Moreover, the identified microorganisms at genus, family, and order levels are thoroughly discussed via refering to CRC-related metagenomic literature. This study not only contributes to our understanding of CRC development, but also highlights the applicability of taxonomy-based G-S-M method in tackling various diseases. © 2025 Elsevier B.V., All rights reserved.Article Citation - WoS: 3Citation - Scopus: 3NeRNA: A Negative Data Generation Framework for Machine Learning Applications of Noncoding RNAs(Pergamon-Elsevier Science Ltd, 2023-06) Orhan, Mehmet Emin; Demirci, Yilmaz Mehmet; Demirci, Mueserref Duygu Sacar; Saçar Demirci, Müşerref DuyguMany supervised machine learning based noncoding RNA (ncRNA) analysis methods have been developed to classify and identify novel sequences. During such analysis, the positive learning datasets usually consist of known examples of ncRNAs and some of them might even have weak or strong experimental validation. On the contrary, there are neither databases listing the confirmed negative sequences for a specific ncRNA class nor standardized methodologies developed to generate high quality negative examples. To overcome this challenge, a novel negative data generation method, NeRNA (negative RNA), is developed in this work. NeRNA uses known examples of given ncRNA sequences and their calculated structures for octal representation to create negative sequences in a manner similar to frameshift mutations but without deletion or insertion. NeRNA is tested individually with four different ncRNA datasets including MicroRNA (miRNA), transfer RNA (tRNA), long noncoding RNA (lncRNA), and circular RNA (circRNA). Furthermore, a species-specific case analysis is per-formed to demonstrate and compare the performance of NeRNA for miRNA prediction. The results of 1000 fold cross-validation on Decision Tree, Naive Bayes and Random Forest classifiers, and deep learning algorithms such as Multilayer Perceptron, Convolutional Neural Network, and Simple feedforward Neural Networks indicate that models obtained by using NeRNA generated datasets, achieves substantially high prediction performance. NeRNA is released as an easy-to-use, updatable and modifiable KNIME workflow that can be downloaded with example datasets and required extensions. In particular, NeRNA is designed to be a powerful tool for RNA sequence data analysis.Article Citation - WoS: 10Citation - Scopus: 14Multi-Agent Context Learning Strategy for Interference-Aware Beam Allocation in mmWave Vehicular Communications(IEEE-Inst Electrical Electronics Engineers Inc, 2024-07) Kose, Abdulkadir; Lee, Haeyoung; Foh, Chuan Heng; Shojafar, MohammadMillimeter wave (mmWave) has been recognized as one of key technologies for 5G and beyond networks due to its potential to enhance channel bandwidth and network capacity. The use of mmWave for various applications including vehicular communications has been extensively discussed. However, applying mmWave to vehicular communications faces challenges of high mobility nodes and narrow coverage along the mmWave beams. Due to high mobility in dense networks, overlapping beams can cause strong interference which leads to performance degradation. As a remedy, beam switching capability in mmWave can be utilized. Then, frequent beam switching and cell change become inevitable to manage interference, which increase computational and signalling complexity. In order to deal with the complexity in interference control, we develop a new strategy called Multi-Agent Context Learning (MACOL), which utilizes Contextual Bandit to manage interference while allocating mmWave beams to serve vehicles in the network. Our approach demonstrates that by leveraging knowledge of neighbouring beam status, the machine learning agent can identify and avoid potential interfering transmissions to other ongoing transmissions. Furthermore, we show that even under heavy traffic loads, our proposed MACOL strategy is able to maintain low interference levels at around 10%.Article Citation - WoS: 16Citation - Scopus: 15Microstructural, Mechanical, Tribological, and Corrosion Behavior of Ultrafine Bio-Degradable Mg/CeO2 Nanocomposites: Machine Learning-Based Modeling and Experiment(Elsevier Sci Ltd, 2023-12) Deka, Surja; Mozafari, Farzin; Mallick, AshisThe present study investigated the microstructural, mechanical, tribological, and corrosion behavior of near-dense and low-volume fraction magnesium-cerium dioxide (Mg/CeO2) (x = 0.5, 1, and 1.5 vol.%) nanocomposites synthesized by in-situ hot extrusion assisted powder metallurgy (PM) process. Results showed a significant improvement in wear resistance for Mg/CeO2 nanocomposite compared to monolithic Mg at varied applied loads. Microindentation tests were performed to access the Vickers microhardness homogeneity along the extrusion direction. The corrosion analysis revealed that introducing ceria nanoparticles enhanced Mg's corrosion resistance and expedited the development of an apatite layer on the surface, providing enhanced protection. A feedforward neural network and Long Short-Term Memory (LSTM) network were also developed to characterize nanocomposites' wear and corrosion behavior.