Scopus İndeksli Yayınlar Koleksiyonu
Permanent URI for this collectionhttps://hdl.handle.net/20.500.12573/395
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Conference Object Citation - Scopus: 1Drug Repositioning via Entity Transformation in Biomedical Knowledge Systems(Springer Science and Business Media Deutschland GmbH, 2025) Erkantarci, B.; Bakal, G.The drug discovery process for known diseases is crucial in bioinformatics, given the extensive clinical trials, regulatory approvals, and high costs. Computational in silico methods are essential to mitigate these challenges, as they help identify promising drug candidates, thereby reducing the time and cost associated with drug discovery. An effective strategy in this domain is drug repositioning, where existing drugs, already approved for one disease, are repurposed for treating another. This approach is advantageous as it leverages the established safety profiles of existing drugs, avoiding toxic effects on human metabolism. In this effort, we employed a translational entity embedding-based neural network model to advance drug repositioning efforts. We utilize the Semantic Medline Database (SemMedDB) as the primary source of biomedical entity relationships for model training. The model is validated using repoDB, a gold standard dataset for drug repositioning. Technically, the model will learn to minimize the vector distance between related entities. This distance will serve as the basis for predicting potential drug-disease pairs in drug repositioning, offering a novel computational method to expedite the drug discovery process. © 2025 Elsevier B.V., All rights reserved.Book Part Citation - Scopus: 3Deep Learning Based Formation Control of Drones(Springer Science and Business Media Deutschland GmbH, 2021) Kabore, Kader Monhamady; Guler, SametRobot swarms can accomplish demanding missions fast, efficiently, and accurately. For a robust operation, robot swarms need to be equipped with reliable localization algorithms. Usually, the global positioning system (GPS) and motion capture cameras are employed to provide robot swarms with absolute position data with high precision. However, such infrastructures make the robots dependent on certain areas and hence reduce robustness. Thus, robots should have onboard localization capabilities to demonstrate a swarm behavior in challenging scenarios such as GPS-denied environments. Motivated by the need for a reliable onboard localization framework for robot swarms, we present a distance and vision-based localization algorithm integrated into a distributed formation control framework for three-drone systems. The proposed approach is established upon the bearing angles and the relative distances between the pairs of drones in a cyclic formation where each drone follows its coleader. We equip each drone with a monocular camera sensor and derive the bearing angle between a drone and its coleader with the recently developed deep learning algorithms. The onboard measurements are then relayed back to the formation control algorithm in which every drone computes its control action in its own frame based on its neighbors only, forming a completely distributed architecture. The proposed approach enables three-drone systems to perform in coordination indepen- dent of any external infrastructure. We validate the performance of our approach in a realistic simulation environment. © 2021 Elsevier B.V., All rights reserved.