Scopus İndeksli Yayınlar Koleksiyonu

Permanent URI for this collectionhttps://hdl.handle.net/20.500.12573/395

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Publisher: search.filters.publisher.Springer International PublishingScopus Q: search.filters.scopusQuartile.Q4

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  • Conference Object
    Citation - Scopus: 2
    The Influence of Plastic Deformation Mechanisms on the Adhesion Behavior and Collagen Formation in Osteoblast Cells
    (Springer International Publishing, 2018) Uzer, B.; Monte, Felipe Alves Do; Awad, Kamal R.; Aswath, Pranesh; Varanasi, Venu Gopal; Canadinc, Demircan
    In many of biomedical applications, the implant might get in direct contact with the bone tissue where the osteogenesis needs to be stimulated. If osteoblasts can not successfully attach on the implant surface, the bone might resorb and implant can fail. In the current study MC3T3 cells were cultured on the 316L stainless steel samples which were deformed up to four different strain levels (5, 15, 25 and 35%) to activate plastic deformation mechanisms (slip and twinning) in different volume fractions. Scanning electron microscopy (SEM) images showed that cells adhered and spread significantly on the 25 and 35% deformed samples owing to the greater surface roughness and energy provided by the increased density of micro-deformation mechanisms which promoted the formation of focal contacts. In addition, significant amount of collagen formation was observed on the sample deformed up to 25% of strain which can be due to the ideal match of the surface roughness and collagen molecules. Overall these results show that material’s microstructure can be manipulated through plastic deformation mechanisms in order to enhance the cell response and collagen deposition. As a result long lasting implants could be obtained which would eliminate additional surgical interventions and provide a successful treatment. © 2018 Elsevier B.V., All rights reserved.
  • Book Part
    Citation - Scopus: 2
    Design of Bio-Joint Shaped Knee Exoskeleton Assisting for Walking and Sit-to
    (Springer International Publishing, 2018-10-14) Kapci, Mehmet Fazil; Unal, Ramazan
    In this study, a bio-joint shaped knee joint exoskeleton is presented. This design is meant for avoiding misalignment of the exoskeleton joint with the biological knee joint. For this purpose a cam mechanism has been designed to prevent the misalignment from translation of the femur on tibia. Additionally, walking and sit-to-stance is passively assisted with a spring element that is activated with the heel contact. A single spring is used for both walking and sit-to-stance, due to the similar characteristics of the gait cycle and initial phases of the sit-to-stance in joint stiffness. © 2018 Elsevier B.V., All rights reserved.
  • Book Part
    Citation - Scopus: 7
    ANT-M: Design of Passive Lower-Limb Exoskeleton for Weight-Bearing Assistance in Industry
    (Springer International Publishing, 2018-10-14) Guncan, Berkay; Unal, Ramazan
    This study describes the optimized design of a passive lower limb exoskeleton for workers in the industry. The exoskeleton is aimed at helping workers who carry heavy loads, by supporting their posture and reducing stress in their knees which would prevent future injuries. However, most of the previous passive designs are insufficient in a way that they are bulky. Therefore, this study is focused on achieving lightweight passive exoskeleton. Topology optimization has been carried out to reach this goal. The results are validated using finite elements methods, in ANSYS environment. © 2018 Elsevier B.V., All rights reserved.