Scopus İndeksli Yayınlar Koleksiyonu
Permanent URI for this collectionhttps://hdl.handle.net/20.500.12573/395
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Conference Object Citation - Scopus: 1The Identification of Discriminative Single Nucleotide Polymorphism Sets for the Classification of Behçet's Disease(Institute of Electrical and Electronics Engineers Inc., 2018-09) Görmez, Yasin; Işik, Yunus Emre; Bakir-Güngör, BurcuBehçet's disease is a long-term multisystem inflammatory disorder, characterized by recurrent attacks affecting several organs. As the genotyping individuals get cheaper and easier following the developments in genomic technologies, genome-wide association studies (GWAS) emerged. By this means, via studying big-sized case-control groups for a specific disease, potential genetic variations, single nucleotide polymorphisms (SNPs) are identified. Although several genetic risk factors are identified for Behçet's disease with the help of these studies via scanning around a million of SNPs, these variations could only explain up to 20% of the disease's genetic risk. In this study, for Behçet's disease classification, via comparing all the SNPs genotyped in GWAS, with the SNPs selected via using genetic knowledge, gain ratio and information gain; both reduction in the feature size and improvement in the classification accuracy is aimed. Also, using different classification algorithms such as random forest, k-nearest neighbour and logistic regression, their effects on the classification accuracy are investigated. Our results showed that compared to other feature selection methods, with at least 81% success rate, the selection of the SNPs using the genetic information (of their GWAS p-values, indicating the significance of the SNP against the disease) provides 15% to 42% improvement in all classification algorithms. This improvement is statistically sound. While gain ratio and information gain feature selection techniques yield similar classification accuracies, the models using all SNPs could not exceed 50% accuracies and results in the worst performance. © 2019 Elsevier B.V., All rights reserved.Conference Object Citation - Scopus: 5Identifying Taxonomic Biomarkers of Colorectal Cancer in Human Intestinal Microbiota Using Multiple Feature Selection Methods(Institute of Electrical and Electronics Engineers Inc., 2022-09-07) Jabeer, Amhar; Kocak, Aysegul; Akkaş, Huseyin; Yenisert, Ferhan; Nalbantoĝlu, Özkan Ufuk; Yousef, Malik; Bakir-Güngör, Burcu; Bakir Gungor, BurcuA variety of bacterial species called gut microbiota work together to maintain a steady intestinal environment. The gastrointestinal tract contains tremendous amount of different species including archaea, bacteria, fungi, and viruses. While these organisms are crucial immune system stabilizers, the dysbiosis of the intestinal flora has been related to gastrointestinal disorders including Colorectal cancer (CRC), intestinal cancer, irritable bowel syndrome and inflammatory bowel disease. In the last decade, next-generation sequencing (NGS) methods have accelerated the identification of human gut flora. CRC is a deathly condition that has been on the rise in the last century, affecting half a million people each year. Since early CRC diagnosis is critical for an effective treatment, there is an immediate requirement for a classification system that can expedite CRC diagnosis. In this study, via analyzing the available metagenomics data on CRC, we aim to facilitate the CRC diagnosis via finding biomarkers linked with CRC, and via building a classification model. We have obtained the metagenomic sequencing data of the healthy individuals and CRC patients from a metagenome-wide association analysis and we have classified this data according to the disease stages. Conditional Mutual Information Maximization (CMIM), Fast Correlation Based Filter (FCBF), Extreme Gradient Boosting (XGBoost), min redundancy max relevance (mRMR), Information Gain (IG) and Select K Best (SKB) feature selection algorithms were utilized to cope with the complexity of the features. We observed that the SKB, IG, and XGBoost techniques made significant contributions to decrease the microbiota in use for CRC diagnosis, thereby reducing cost and time. We realized that our Random Forest classifier outperformed Adaboost, Support Vector Machine, Decision Tree, Logitboost and stacking ensemble classifiers in terms of CRC classification performance. Our results reiterated some known and some potential microbiome associated mechanisms in CRC, which could aid the design of new diagnostics based on the microbiome. © 2022 Elsevier B.V., All rights reserved.Conference Object Benchmarking CNN Architectures for Eye Disease Detection With Transfer Learning Techniques(Institute of Electrical and Electronics Engineers Inc., 2025-06-27) Keles, Tolgahan; Aykanat, Muhammet Ali; Kurban, RifatIn this study, convolutional neural networks (CNN)-based approaches were compared to classify eye diseases using transfer learning techniques. A series of data augmentation strategies, including random rotation, shifting, shearing, zooming, and horizontal flipping, were applied to increase the training data's robustness and diversity. Several state-of-the-art CNNs, including ResNet50, VGG19, EfficientNetB0, Xception, InceptionV3, DenseNet121, MobileNetV2, NASNetMobile, and ConvNeXtBase, were fine-tuned through transfer learning. During training, models were evaluated based on their accuracy, training time, and validation performance, while early stopping mechanisms were employed to prevent overfitting. Experimental results demonstrated that DenseNet121 achieved the highest validation accuracy (72%) during the training phase and the best test set performance with an accuracy of 68% and an AUC-ROC of 0.93. MobileNetV2, on the other hand, provided a strong balance between classification accuracy (65%) and low inference time (7.28 ms), making it appropriate for real-time uses. The findings highlight the importance of selecting appropriate architectures by considering both predictive performance and computational efficiency, particularly in the context of medical imaging, where real-world deployment constraints are critical. © 2025 Elsevier B.V., All rights reserved.Conference Object Citation - Scopus: 19A Novel Feature Design and Stacking Approach for Non-Technical Electricity Loss Detection(Institute of Electrical and Electronics Engineers Inc., 2018-05) Aydin, Zafer; Güngör, Vehbi ÇağrıNon-technical electricity losses continue to jeopardize economic and social well-being of many countries. In this work, we develop machine learning classifiers that can identify anomalous electricity consumption in Turkey. Starting from weekly electricity usage data, we develop new features that capture statistical and frequency domain characteristics of the customers and their consumption patterns. We analyze the effect of reducing number of feature descriptors through dimensionality reduction and feature selection techniques. To overcome the class imbalance problem, we implement several ensemble methods and compare their prediction accuracy to those of the standard classifiers. The proposed features and combining strengths of different classifiers bring significant improvements on performance metrics, which is demonstrated through detailed simulations on shopping mall sector. We anticipate that advances in this field will contribute to the economies considerably. © 2018 Elsevier B.V., All rights reserved.Conference Object Citation - Scopus: 3A Hybrid Adaptive Neuro-Fuzzy Inference System (ANFIS) Approach for Professional Bloggers Classification(Institute of Electrical and Electronics Engineers Inc., 2019-11) Asim, Yousra; Raza, Basit; Malik, Ahmad Kamran Kamran; Shahid, Ahmad Raza; Faheem, Muhammed Yasir; Kumar, Y. J.Despite their small numbers, some users of the online social networks demonstrate the ability to influence others. Bloggers are one of such kind of users that through their ideas and opinions on different topics, influence other users. Their identification may be beneficial for several purposes, such as online marketing for products. Much effort has been expanded towards finding the impact of such bloggers within the blogging community. We have expanded on their work by identifying influential bloggers using labeled data. We have improved upon the accuracy of the classification of professional and nonprofessional bloggers. We have made use of Adaptive Neuro-Fuzzy Inference System (ANFIS), and the Fuzzy Inference System (FIS) models. Their performance has been gauged and compared with the existing techniques and approaches, such as an Artificial Neural Network (ANN), Alternating Decision Tree (ADTree) algorithm, and Classification Based on Associations (CBA) algorithm. Adaptive techniques (ANFIS and ANN) are found better than the aforementioned rule-based classifiers. The FIS model outperformed the CBA algorithm, but showed similar performance to the ADTree algorithm. Our proposed ANFIS model showed improved results in terms of performance measures with 93% accuracy for blogger classification. © 2020 Elsevier B.V., All rights reserved.Conference Object Citation - WoS: 3Citation - Scopus: 13NSEM: Duygu Analizi için Özgün Yıǧınlanmiş Topluluk Yöntemi(Institute of Electrical and Electronics Engineers Inc., 2018-09) Işik, Yunus Emre; Görmez, Yasin; Kaynar, Oǧuz; Aydin, Zafer; Emre Isik, YunusToday, people often share their ideas, opinions and feelings through forums, social media sites, blogs and similar platforms. For this reason, access to these data has become very easy. Increase in the number of shares makes it possible to analyze and use these data in terms of marketing and politics. However, due to the large number of data, it is impossible that this analysis will be done by humans. Determination of what type of emotion is included automatically is done by sentiment analysis methods. In these methods, the text is defined as a mathematical vector and classified by machine learning methods. Ensemble methods are one of the most important methods used as classifiers in sentiment analysis. In these methods, a classifier error is tried to be solved by another classifier. In sentiment analysis, the feature vector that describes the text is as important as the classifier. Feature vectors obtained using different methods can make mistakes in different places. For this reason, in this study, NSEM is proposed for sentiment analysis, which is a new ensemble method that uses 2 different classifiers and 2 different feature extraction methods. As a result of the analysis, the proposed method is the most successful method with an accuracy rate of 79.1%. © 2019 Elsevier B.V., All rights reserved.Conference Object Population Specific Classification of Colorectal Cancer With Meta-Analysis of Metagenomic Data(Institute of Electrical and Electronics Engineers Inc., 2023-10-11) Temiz, Mustafa; Yousef, Malik; Bakir-Güngör, BurcuAdvances in next-generation sequencing and '-omics' technologies makes it possible to characterize the human gut microbiome. While some of these microorganisms are important regulators of our immune system, modulation of the microbiota leads to a variety of diseases. Colorectal cancer (CRC), the third most common cancer worldwide, is caused by genetic mutations, environmental conditions, and abnormalities in the gut microbiota. Using various machine learning methods and meta-analysis techniques, this study aims to build a classification model that can help in CRC diagnosis by analyzing metagenomic datasets of different populations obtained at the species level. Using 8 different countries and 9 different metagenomic datasets, 3 different meta-analyzes are performed: within-population, cross-population, and one population is selected for testing and the rest is used as a training dataset (LODO). For CRC classification, 4 different classification algorithms (Random Forest (RF), Logitboost, Adaboost, and Decision Tree (DT)) are used. The best performance among these methods was obtained with the Random Forest algorithm with an AUC of 0.98 by using JP for the training data set and JPN populations for the test data set in the cross-population performance evaluation. © 2023 Elsevier B.V., All rights reserved.Conference Object Citation - Scopus: 3İki Durumlu Bir Beyin Bilgisayar Arayüzünde Özellik Çıkarımı ve Sınıflandırma(Institute of Electrical and Electronics Engineers Inc., 2016-10) Altindis, Fatih; Yilmaz, BulentBrain Computer Interface (BCI) technology is used to help patients who do not have control over motor neurons such as ALS or paralyzed patients, to communicate with outer world. This work aims to classify motor imageries using real-time EEG dataset, which was published by Graz University, Austria. The dataset consists of two-channel EEG signals of right-hand movement imagery and left-hand movement imagery of 8 subjects. There are a total of 120 motor imagery trials (60 left and 60 right) EEG signals recorded from each subject. EEG signals are filtered and feature vectors were extracted that consist of 24, 32 and 40 relative band power values (RBPV). In this work, feature vectors classified by three different methods, linear discriminant analysis (LDA), K nearest neighbor (KNN) and support vector machines (SVM). Results show that best performance was achieved by 24 RBPV feature vector and LDA classification method. © 2017 Elsevier B.V., All rights reserved.Conference Object Citation - Scopus: 2Makine Öǧrenmesi Teknikleri Ile İnternet Servis Saǧlayıcısı için Müşteri Kayıp Tahmini(Institute of Electrical and Electronics Engineers Inc., 2020-09) Göy, Gökhan; Kolukisa, Burak; Bahçevan, Cenk Anıl; Güngör, Vehbi ÇağrıWith the developing technology in every fields, a competitive marketing environment has been arised. In this competitive environment, analyzing customer behavior has become vital. In particular, the ability to easily change any service provider has become very critical for the company to continue its existence. At the same time, the amount of financial resources spent on retaining customers much less than to obtain new clients. In this context, the traditional methods of examining vast amount of data obtained today for establishing decision support systems have lost their validities. In this study, we used a dataset which is provided by TurkNet serving as an internet service provider in Turkey. Various preprocessing steps has performed on this dataset and then classification algorithms ran. Afterwards results have obtained and compared. The results of these experiments analyzed in terms of the area under the curve value. In this context, the most successful classifier algorithm has been determined as the Random Trees algorithm with a value of 0.936. © 2020 Elsevier B.V., All rights reserved.Conference Object Citation - WoS: 8Citation - Scopus: 9Meme Kanseri Histopatolojik Görüntülerinin Bilgisayar Destekli Sınıflandırılması(Institute of Electrical and Electronics Engineers Inc., 2017-10) Aksebzeci, Bekir Hakan; Kayaaltı, ÖmerNowadays, one of the most common types of cancer is breast cancer. The early and accurate diagnosis of breast cancer has great importance in the treatment of the disease. In the diagnosis of breast cancer, histopathological analysis of cell and tissue specimens taken by biopsy is considered as the gold standard. Histopathological analysis is a tedious process that is highly dependent on the knowledge and experience of the pathologists. In this study; it is aimed to develop a computer-Aided system that can reduce the workload of pathologists and help them in their diagnosis. An image set containing benign and malignant tumor images of breast cancer has been studied. To perform texture analysis on tumor images; first order statistics, Gabor and gray-level co-occurrence matrix (GLCM) feature extraction methods have been applied. Then, various classifiers were applied to the obtained feature matrices and their performances were compared. The highest classification accuracy was achieved 82.06% by Random Forests classifier with feature combination of Gabor and GLCM methods. The results presented here show that computer-Assisted diagnosis of breast cancer is a promising field. © 2018 Elsevier B.V., All rights reserved.