Scopus İndeksli Yayınlar Koleksiyonu

Permanent URI for this collectionhttps://hdl.handle.net/20.500.12573/395

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  • Article
    Citation - Scopus: 63
    Energy Efficient and Reliable Data Gathering Using Internet of Software-Defined Mobile Sinks for WSNS-Based Smart Grid Applications
    (Elsevier B.V., 2019-10) Faheem, Muhammed Yasir; Butt, Rizwan Aslam; Raza, Basit; Ashraf, Muhammad Waqar; Ngadi, M. A.; Güngör, Vehbi Çağrı
    The smart grid is an emerging concept that introduces innovative ways to handle the power quality and reliability issues for both service provider and consumers. The key aims of the smart grid (SG) in smart cities (SCs) is to preserve a certain level of residents’ life quality and support the entire spectrum of their economic activities. In this paper, we present a novel Energy Efficient and Reliable Data Gathering Routing Protocol (ODGRP) for wireless sensor networks (WSNs)-based smart grid applications. The developed scheme employs a software-defined centralized controller and multiple mobile sinks for energy efficient and reliable data gathering from WSNs in the SG. The extensive simulation results conducted through the EstiNet 9.0 show that the designed scheme outperforms existing approaches and achieves its defined goals for event-driven applications in the SG. © 2019 Elsevier B.V., All rights reserved.
  • Article
    Citation - Scopus: 6
    Amelioration Potential of Synthetic Oxime Chemical Cores Against Multiple Sclerosis and Alzheimer's Diseases: Evaluation in Aspects of in Silico and in Vitro Experiments
    (Elsevier B.V., 2024-12) Yilmaz, Anil; Koca, Murat; Ercan, Selami; Acar, Özden Ozgun; Boǧa, Mehmet; Sen, Alaattin; Kurt, Adnan
    Alzheimer disease (AD) and multiple sclerosis (MS) are inflammatory neurological disorders. The main symptom of AD is dementia, and the main symptoms of MS are vertigo, sexual dysfunction, cognitive problems, and fatigue. Today, millions of people are affected by AD and MS, and the number is growing day by day. However, there are not any accurate remedies for both disorders. For this reason, discovering novel drug molecules against neurological disorders such as AD and MS is essential and precious. Oximes and benzofurans exhibit many pharmacological effects including anti-inflammatory and neurological activities. Thus, several novel compounds bearing oxime and benzofuran chemical cores were designed and synthesized, and their in vitro anticholinesterase activities were investigated in our previous study. A number of the synthesized molecules showed excellent anticholinesterase activity against both AChE and BChE enzymes. The mentioned study constituted a background for this study. In this study, we picked different chemical skeletons among all the synthesized molecules to conduct further in silico and in vitro experiments. In order to support our in vitro anticholinesterase findings, we also examined in silico anti-Alzheimer activity of the selected molecules. In addition, in silico and in vitro activities against MS disease of the synthesized molecules were investigated. Molecule 4 extraordinarily showed outstanding activity against AD disease both in silico and in vitro, as well as in silico activity against MS disease. This feature makes molecule 4 a possible drug lead molecule which is very limited in the market. On the other hand, molecule 1, a less substituted oxime skeleton, demonstrated the strongest in vitro activity against MS disease through in vitro anti-inflammatory effect. As an observation, molecule 4 was determined to be the most promising molecule to focus on in the further steps. © 2024 Elsevier B.V., All rights reserved.
  • Article
    Citation - WoS: 5
    Citation - Scopus: 5
    Formation of a Very High-Density Amorphous Phase of Carbon and Its Crystallization into a Simple Cubic Structure at High Pressure
    (Elsevier B.V., 2021) Durandurdu, M.
    We report a direct computational evidence of a two-step transformation sequence for tetrahedral amorphous carbon (ta-C) with increasing pressure. First, ta-C gradually transforms into a very high-density amorphous phase (VHDA) phase. Second, the VDHA phase converts into a simple cubic (SC) crystal. The structural defects formed during the high-pressure treatment play important roles for the formation and stabilization of the SC structure, rather than favorable the SC4 crystal. These phase transformations are reversible. © 2021 Elsevier B.V., All rights reserved.