Scopus İndeksli Yayınlar Koleksiyonu
Permanent URI for this collectionhttps://hdl.handle.net/20.500.12573/395
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Article GraphUnet-SS: A Novel Deep Learning Model for Protein Secondary Structure Prediction Based on U-Net Architecture(Elsevier Ltd, 2026-04) Aydin, Zafer; Görmez, Yasin; Sabzekar, MostafaArticle Non-Contact Acoustic Screening for Sleep Apnea: A Subject-Aware Deep Learning Approach(Springer Science and Business Media Deutschland GmbH, 2026-02-11) Aygün Çakıroğlu, M.; Kizilkaya Aydoǧan, E.; Bolatturk, Ö.F.; Aydoğan, S.; Ismailoǧullari, S.; Delice, Y.Purpose: To explore the feasibility of using camera-derived, non-contact audio synchronized with PSG for clinically relevant sleep-apnea classification, and to benchmark compact deep models under a subject-aware design using a previously unstudied, real-world dataset. Methods: Thirty-two adults underwent simultaneous polysomnography (PSG) and camera-based non-contact audio recording. The synchronized audio segments were used to train and compare three compact deep-learning architectures (convolutional, attention-augmented, and transformer-based) under a subject-aware evaluation design that prevented identity leakage. Model performance and calibration were assessed at both segment and subject levels using standard statistical tests. Results: Subject-level evaluation was based on a very small, imbalanced test set of six subjects (one positive). Within this limited yet previously unstudied local dataset, the CNN_trans model achieved an apparent perfect ranking performance (AUC = 1.00; 95% CI 0.00–1.00), though this likely reflects the small, imbalanced test cohort, with recall = 1.00 and precision = 0.55. The wide confidence interval reflects substantial statistical uncertainty, and DeLong comparisons showed no significant AUC difference between CNN_trans and CNN_att (ΔAUC = − 0.042; p = 0.43). Conclusion: PSG-synchronized, non-contact audio supports accurate and well-calibrated sleep-apnea classification with compact deep models. This subject-aware evaluation suggests that contactless acoustic monitoring may have potential clinical relevance, motivating larger, multi-site validation. © The Author(s), under exclusive licence to Springer Nature Switzerland AG 2026.Article Deep-Learning Detection of Open-Apex Teeth on Panoramic Radiographs Using YOLO Models(Springer, 2025-12-23) Edik, Merve; Celebi, Fatma; Cukurluoglu, AykaganObjectivesThe use of deep learning in detecting teeth with open apices can prevent the need for additional radiographs for patients. The presented study aims to detect open-apex teeth using You Only Look Once (YOLO)-based deep learning models and compare these models.MethodsA total of 966 panoramic radiographs were included in the study. Open-apex teeth in panoramic radiographs were labeled. During the labeling process, they were divided into 6 classes in the maxilla and mandible, namely incisors, premolars, and molars. AI models YOLOv3, YOLOv4, and YOLOv5 were used. To evaluate the performance of the three detection models, both overall and separately for each class in the test dataset, precision, recall, average precision (mAP), and F1 score were calculated.ResultsYOLOv4 achieved the highest overall performance with a mean average precision (mAP) of 87.84% at IoU (Intersection over Union) 0.5 (mAP@0.5), followed by YOLOv5 with 85.6%, and YOLOv3 with 84.46%. Regarding recall, YOLOv4 also led with 90%, while both YOLOv3 and YOLOv5 reached 89%. Moreover, the F1 score was the highest for YOLOv4 (0.87), followed by YOLOv3 (0.86) and YOLOv5 (0.85).ConclusionsIn this study, YOLOv3, YOLOv4, and YOLOv5 were evaluated for the detection of open-apex teeth, and their mAP, recall, and F1 scores exceeded 84%. Deep learning-based systems can provide faster and more accurate results in the detection of open-apex teeth. This may help reduce the need for additional radiographs from patients and aid dentists by saving time.Article Citation - WoS: 3Citation - Scopus: 9Probabilistic Assessment of Wind Power Plant Energy Potential Through a Copula-Deep Learning Approach in Decision Trees(Cell Press, 2024-04) Sahin, Kubra Nur; Sutcu, MuhammedIn the face of environmental degradation and diminished energy resources, there is an urgent need for clean, affordable, and sustainable energy solutions, which highlights the importance of wind energy. In the global transition to renewable energy sources, wind power has emerged as a key player that is in line with the Paris Agreement, the Net Zero Target by 2050, and the UN 2030 Goals, especially SDG-7. It is critical to consider the variable and intermittent nature of wind to efficiently harness wind energy and evaluate its potential. Nonetheless, since wind energy is inherently variable and intermittent, a comprehensive assessment of a prospective site's wind power generation potential is required. This analysis is crucial for stakeholders and policymakers to make well-informed decisions because it helps them assess financial risks and choose the best locations for wind power plant installations. In this study, we introduce a framework based on Copula-Deep Learning within the context of decision trees. The main objective is to enhance the assessment of the wind power potential of a site by exploiting the intricate and non-linear dependencies among meteorological variables through the fusion of copulas and deep learning techniques. An empirical study was carried out using wind power plant data from Turkey. This dataset includes hourly power output measurements as well as comprehensive meteorological data for 2021. The results show that acknowledging and addressing the non-independence of variables through innovative frameworks like the Copula-LSTM based decision tree approach can significantly improve the accuracy and reliability of wind power plant potential assessment and analysis in other real-world data scenarios. The implications of this research extend beyond wind energy to inform decision-making processes critical for a sustainable energy future.Article Citation - WoS: 13Citation - Scopus: 20IGPRED: Combination of Convolutional Neural and Graph Convolutional Networks for Protein Secondary Structure Prediction(Wiley, 2021-05-25) Gormez, Yasin; Sabzekar, Mostafa; Aydin, ZaferThere is a close relationship between the tertiary structure and the function of a protein. One of the important steps to determine the tertiary structure is protein secondary structure prediction (PSSP). For this reason, predicting secondary structure with higher accuracy will give valuable information about the tertiary structure. Recently, deep learning techniques have obtained promising improvements in several machine learning applications including PSSP. In this article, a novel deep learning model, based on convolutional neural network and graph convolutional network is proposed. PSIBLAST PSSM, HHMAKE PSSM, physico-chemical properties of amino acids are combined with structural profiles to generate a rich feature set. Furthermore, the hyper-parameters of the proposed network are optimized using Bayesian optimization. The proposed model IGPRED obtained 89.19%, 86.34%, 87.87%, 85.76%, and 86.54% Q3 accuracies for CullPDB, EVAset, CASP10, CASP11, and CASP12 datasets, respectively.Article Citation - WoS: 3Citation - Scopus: 6IGPRED-Multitask: A Deep Learning Model to Predict Protein Secondary Structure, Torsion Angles and Solvent Accessibility(IEEE Computer Soc, 2023-03-01) Gormez, Yasin; Aydin, ZaferProtein secondary structure, solvent accessibility and torsion angle predictions are preliminary steps to predict 3D structure of a protein. Deep learning approaches have achieved significant improvements in predicting various features of protein structure. In this study, IGPRED-Multitask, a deep learning model with multi task learning architecture based on deep inception network, graph convolutional network and a bidirectional long short-term memory is proposed. Moreover, hyper-parameters of the model are fine-tuned using Bayesian optimization, which is faster and more effective than grid search. The same benchmark test data sets as in the OPUS-TASS paper including TEST2016, TEST2018, CASP12, CASP13, CASPFM, HARD68, CAMEO93, CAMEO93_HARD, as well as the train and validation sets, are used for fair comparison with the literature. Statistically significant improvements are observed in secondary structure prediction on 4 datasets, in phi angle prediction on 2 datasets and in psi angel prediction on 3 datasets compared to the state-of-the-art methods. For solvent accessibility prediction, TEST2016 and TEST2018 datasets are used only to assess the performance of the proposed model.Article Citation - WoS: 2Citation - Scopus: 4Deep-Learning AI-Model for Predicting Dental Plaque in the Young Permanent Teeth of Children Aged 8-13 Years(MDPI, 2025-04-07) Tez, Banu Cicek; Guzel, Yasin; Eliacik, Bahar Basak Kiziltan; Aydin, Zafer; Kızıltan Eliaçık, Bahar BaşakBackground/Objectives: Dental plaque is a significant contributor to various prevalent oral health conditions, including caries, gingivitis, and periodontitis. Consequently, its detection and management are of paramount importance for maintaining oral health. Manual plaque assessment is time-consuming, error-prone, and particularly challenging in uncooperative pediatric patients. These limitations have encouraged researchers to seek faster, more reliable methods. Accordingly, this study aims to develop a deep learning model for detecting and segmenting plaque in young permanent teeth and to evaluate its diagnostic precision. Methods: The dataset comprises 506 dental images from 31 patients aged between 8 and 13 years. Six state-of-the-art models were trained and evaluated using this dataset. The U-Net Transformer model, which yielded the best performance, was further compared against three experienced pediatric dentists for clinical feasibility using 35 randomly selected images from the test set. The clinical trial was registered on under the ID NCT06603233 (1 June 2023). Results: The Intersection over Union (IoU) score of the U-Net Transformer on the test set was measured as 0.7845, and the p-values obtained from the three t-tests conducted for comparison with dentists were found to be below 0.05. Compared with three experienced pediatric dentists, the deep learning model exhibited clinically superior performance in the detection and segmentation of dental plaque in young permanent teeth. Conclusions: This finding highlights the potential of AI-driven technologies in enhancing the accuracy and reliability of dental plaque detection and segmentation in pediatric dentistry.Article Citation - Scopus: 8Building a Challenging Medical Dataset for Comparative Evaluation of Classifier Capabilities(Elsevier Ltd, 2024-08) Bozkurt, Berat; Coskun, Kerem; Bakal, GokhanSince the 2000s, digitalization has been a crucial transformation in our lives. Nevertheless, digitalization brings a bulk of unstructured textual data to be processed, including articles, clinical records, web pages, and shared social media posts. As a critical analysis, the classification task classifies the given textual entities into correct categories. Categorizing documents from different domains is straightforward since the instances are unlikely to contain similar contexts. However, document classification in a single domain is more complicated due to sharing the same context. Thus, we aim to classify medical articles about four common cancer types (Leukemia, Non-Hodgkin Lymphoma, Bladder Cancer, and Thyroid Cancer) by constructing machine learning and deep learning models. We used 383,914 medical articles about four common cancer types collected by the PubMed API. To build classification models, we split the dataset into 70% as training, 20% as testing, and 10% as validation. We built widely used machine-learning (Logistic Regression, XGBoost, CatBoost, and Random Forest Classifiers) and modern deep-learning (convolutional neural networks - CNN, long short-term memory - LSTM, and gated recurrent unit - GRU) models. We computed the average classification performances (precision, recall, F-score) to evaluate the models over ten distinct dataset splits. The best-performing deep learning model(s) yielded a superior F1 score of 98%. However, traditional machine learning models also achieved reasonably high F1 scores, 95% for the worst-performing case. Ultimately, we constructed multiple models to classify articles, which compose a hard-to-classify dataset in the medical domain. © 2024 Elsevier B.V., All rights reserved.