Scopus İndeksli Yayınlar Koleksiyonu
Permanent URI for this collectionhttps://hdl.handle.net/20.500.12573/395
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Article Citation - WoS: 5Citation - Scopus: 5Novel Antimicrobial Peptide Design Using Motif Match Score Representation(IEEE Computer Soc, 2024-11) Soylemez, Ummu Gulsum; Yousef, Malik; Kesmen, Zulal; Bakir-Gungor, BurcuAntimicrobial peptides (AMPs) have drawn the interest of the researchers since they offer an alternative to the traditional antibiotics in the fight against antibiotic resistance and they exhibit additional pharmaceutically significant properties. Recently, computational approaches attemp to reveal how antibacterial activity is determined from a machine learning perspective and they aim to search and find the biological cues or characteristics that control antimicrobial activity via incorporating motif match scores. This study is dedicated to the development of a machine learning framework aimed at devising novel antimicrobial peptide (AMP) sequences potentially effective against Gram-positive/Gram-negative bacteria. In order to design newly generated sequences classified as either AMP or non-AMP, various classification models were trained. These novel sequences underwent validation utilizing the "DBAASP: strain-specific antibacterial prediction based on machine learning approaches and data on AMP sequences" tool. The findings presented herein represent a significant stride in this computational research, streamlining the process of AMP creation or modification within wet lab environments.Article Citation - WoS: 2Citation - Scopus: 2Machine-Generated Hierarchical Structure of Human Activities to Reveal How Machines Think(IEEE-Inst Electrical Electronics Engineers Inc, 2021) Altin, Mahsun; Gursoy, Furkan; Xu, LinaDeep-learning based computer vision models have proved themselves to be ground-breaking approaches to human activity recognition (HAR). However, most existing works are dedicated to improve the prediction accuracy through either creating new model architectures, increasing model complexity, or refining model parameters by training on larger datasets. Here, we propose an alternative idea, differing from existing work, to increase model accuracy and also to shape model predictions to align with human understandings through automatically creating higher-level summarizing labels for similar groups of human activities. First, we argue the importance and feasibility of constructing a hierarchical labeling system for human activity recognition. Then, we utilize the predictions of a black box HAR model to identify similarities between different activities. Finally, we tailor hierarchical clustering methods to automatically generate hierarchical trees of activities and conduct experiments. In this system, the activity labels on the same level will have a designed magnitude of accuracy and reflect a specific amount of activity details. This strategy enables a trade-off between the extent of the details in the recognized activity and the user privacy by masking some sensitive predictions; and also provides possibilities for the use of formerly prohibited invasive models in privacy-concerned scenarios. Since the hierarchy is generated from the machine's perspective, the predictions at the upper levels provide better accuracy, which is especially useful when there are too detailed labels in the training set that are rather trivial to the final prediction goal. Moreover, the analysis of the structure of these trees can reveal the biases in the prediction model and guide future data collection strategies.Article Citation - WoS: 26Citation - Scopus: 27ATOM: AI-Powered Sustainable Resource Management for Serverless Edge Computing Environments(IEEE-Inst Electrical Electronics Engineers Inc, 2024-11) Golec, Muhammed; Gill, Sukhpal Singh; Cuadrado, Felix; Parlikad, Ajith Kumar; Xu, Minxian; Wu, Huaming; Uhlig, SteveServerless edge computing decreases unnecessary resource usage on end devices with limited processing power and storage capacity. Despite its benefits, serverless edge computing's zero scalability is the major source of the cold start delay, which is yet unsolved. This latency is unacceptable for time-sensitive Internet of Things (IoT) applications like autonomous cars. Most existing approaches need containers to idle and use extra computing resources. Edge devices have fewer resources than cloud-based systems, requiring new sustainable solutions. Therefore, we propose an AI-powered, sustainable resource management framework called ATOM for serverless edge computing. ATOM utilizes a deep reinforcement learning model to predict exactly when cold start latency will happen. We create a cold start dataset using a heart disease risk scenario and deploy using Google Cloud Functions. To demonstrate the superiority of ATOM, its performance is compared with two different baselines, which use the warm-start containers and a two-layer adaptive approach. The experimental results showed that although the ATOM required more calculation time of 118.76 seconds, it performed better in predicting cold start than baseline models with an RMSE ratio of 148.76. Additionally, the energy consumption and CO2 emission amount of these models are evaluated and compared for the training and prediction phases.