Scopus İndeksli Yayınlar Koleksiyonu
Permanent URI for this collectionhttps://hdl.handle.net/20.500.12573/395
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Article GenShare: A Blockchain-Based Genomic Data Sharing Platform(Association for Computing Machinery, 2026-01-27) Dedeturk, B.A.; Soran, A.; Bakir-Güngör, B.Every day, hundreds of gigabytes of data are produced due to the exponential growth of next-generation sequencing and omics technologies. By combining omics data with other data types, such as electronic health record data, panomics research is actively attempting to uncover novel and potentially useful biomarkers. For the effective analysis of high-throughput-derived omics data, it is imperative to establish robust and reliable platforms that prioritize ethical considerations while effectively managing privacy, ownership concerns, and the responsible sharing of data. The GenShare model was proposed to provide an efficient platform that fits these needs. GenShare is a hybrid platform that utilizes blockchain technology. Paillier’s homomorphic encryption scheme in tandem with Intel Software Guard Extension (SGX) serves to enable the sharing of genomic data, execution of count queries, and statistical analysis of genomic data while preserving privacy and avoiding compromise of sensitive information. The objective of this paradigm is to confront security and privacy concerns through the integration of homomorphic encryption and SGX, addressing additional challenges associated with Hyperledger Fabric and Ethereum. In pursuit of this objective, the implementation of the system involved establishing the Hyperledger Fabric network, with various workloads employed to assess the network’s efficiency. Consequently, it was hypothesized that the new GenShare model would enhance the data collection and dissemination cycle and serve as a proficient platform catering to the needs of its users. © 2026 Copyright held by the owner/author(s).Conference Object Citation - Scopus: 2Comparative Performance Analysis of Ethereum and Optimism Smart Contracts in Health Insurance(Institute of Electrical and Electronics Engineers Inc., 2024-10-26) Dedeturk, Beyhan Adanur; Dedeturk, Bilge KaganOne type of insurance that people purchase to cover unexpected medical expenses is health insurance. In exchange for premium payments, the insurance company may cover a portion of the insured person's medical expenses, such as prescription medications, hospital stays, and doctor visits. This method makes access to healthcare easier and less expensive. Health insurance systems do, however, have a number of issues, including fair insurance premium calculation, automation, data verification, privacy and security, and cost effectiveness. These issues are starting to be addressed by blockchain technology, particularly with the help of smart contracts. Using a comparison analysis between Ethereum and Optimism smart contracts, this paper demonstrates the performance of health insurance. Simulation of these BC technologies was carried out both on the Sepolia testnet and using Alchemy. Tools and metrics provided to monitor the performance of Alchemy applications, detect errors, and analyze user interactions were used in the measurements. While Ethereum's well-established ecosystem offers robust support for smart contracts, Optimism distinguishes itself as a scalable substitute that delivers quicker transaction speeds and more affordable options. According to the analysis results, the advantages and disadvantages of Ethereum and Optimism are highlighted when it comes to health insurance. © 2025 Elsevier B.V., All rights reserved.