Scopus İndeksli Yayınlar Koleksiyonu
Permanent URI for this collectionhttps://hdl.handle.net/20.500.12573/395
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Article Citation - WoS: 27Citation - Scopus: 30Super Resolution Convolutional Neural Network Based Pre-Processing for Automatic Polyp Detection in Colonoscopy Images(Pergamon-Elsevier Science Ltd, 2021-03) Tas, Merve; Yilmaz, BulentColonoscopy is the most common methodology used to detect polyps on the colon surface. Increasing the image resolution has the potential to improve the automatic colonoscopy based diagnosis and polyp detection and localization. In this study, we proposed a pre-processing approach that uses convolutional neural network based super resolution method (SRCNN) to increase the resolution of the training colonoscopy images before the localization of polyps. We also investigated the use of CNN based models such as the Single Shot MultiBox Detector (SSD) and Faster Regional CNN (RCNN) for real-time polyp detection and localization. Our results showed that using SRCNN method before the training process provides better results in terms of accuracy in both models compared to the low-resolution cases. Furthermore, we reached an F2 score of 0.945 for the correct localization of colon polyps using Faster RCNN with ResNet-101 feature extractor.Article Citation - WoS: 14Citation - Scopus: 15Image-Analysis Based Readout Method for Biochip: Automated Quantification of Immunomagnetic Beads, Micropads and Patient Leukemia Cell(Pergamon-Elsevier Science Ltd, 2020-06) Uslu, Fatma; Icoz, Kutay; Tasdemir, Kasim; Dogan, Refika S.; Yilmaz, BulentFor diagnosing and monitoring the progress of cancer, detection and quantification of tumor cells is utmost important. Beside standard bench top instruments, several biochip-based methods have been developed for this purpose. Our biochip design incorporates micron size immunomagnetic beads together with micropad arrays, thus requires automated detection and quantification of not only cells but also the micropads and the immunomagnetic beads. The main purpose of the biochip is to capture target cells having different antigens simultaneously. In this proposed study, a digital image processing-based method to quantify the leukemia cells, immunomagnetic beads and micropads was developed as a readout method for the biochip. Color, size-based object detection and object segmentation methods were implemented to detect structures in the images acquired from the biochip by a bright field optical microscope. It has been shown that manual counting and flow cytometry results are in good agreement with the developed automated counting. Average precision is 85 % and average error rate is 13 % for all images of patient samples, average precision is 99 % and average error rate is 1% for cell culture images. With the optimized micropad size, proposed method can reach up to 95 % precision rate for patient samples with an execution time of 90 s per image.