Scopus İndeksli Yayınlar Koleksiyonu
Permanent URI for this collectionhttps://hdl.handle.net/20.500.12573/395
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Book Part Citation - Scopus: 2Metal Nanoparticles Via Green Synthesis: A New Cancer Treatment Approach(IGI Global, 2023-11-03) Saylan, Demet; Erdem, İlkerCancer is one of the most abundant lethal diseases globally threatening public health. There is considerable research effort on the prevention, diagnosis, and treatment of cancer. The current practices for cancer treatment are usage of synthetic chemicals (i.e. chemotherapy), radiotherapy, and surgery. Besides these conventional therapies, there are contemporary, innovative approaches, e.g., targeting of the drugs to the cancerous tissues, synergetic enhancement via simultaneous usage of conventional methods, and contemporary methods. Therefore, the process of drug research and development in the field of cancer is increasingly challenging, due to the limited success of current therapies and the constant need to find safer and more effective novel approaches. The utilization of nanotechnology may present new opportunities in cancer treatment. Metal nanoparticles prepared via "bottom-up" approach may be used for triggering the selective cell apoptosis mechanisms for cancerous cells, while sparing healthy cells considerably. © 2024 Elsevier B.V., All rights reserved.Book Part Isothiocyanates as Drug Candidates in Cancer Prevention and Treatment(IGI Global, 2023-06-16) Saylan, Demet; Cebeci, FatmaCancer is the second most common cause of death worldwide. Many methods such as surgery, chemotherapy, radiation therapy, etc. are being used for treatment. Most patients have a combination treatment with chemotherapy along with surgery or radiotherapy or both. Chemotherapy kills cancer cells by preventing them from reproducing, growing, and spreading in the body. Recently, safer alternatives to chemotherapy have been discovered and developed, as most of the drugs used in cancer treatment have side effects and a serious impact on patient comfort. As an alternative, the phytochemicals found in daily consumed plants are attractive candidates for clinical/pre-clinical evaluation because of their higher safety. In this context, certain degradation products of glucosinolates (isothiocyanates) are promising agents for cancer prevention and treatment. © 2023 Elsevier B.V., All rights reserved.