Scopus İndeksli Yayınlar Koleksiyonu
Permanent URI for this collectionhttps://hdl.handle.net/20.500.12573/395
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Conference Object Citation - WoS: 1Citation - Scopus: 1Polyp Localization in Colonoscopy Images Using Vessel Density(Institute of Electrical and Electronics Engineers Inc., 2018-11) Doǧan, Refika Sultan; Yilmaz, BulentIn this paper, we present a new approach for polyp localization in colonoscopy images. This approach is based on the determination of the polyp location using the vessel density in colon images. Primarily, we used pre-processing procedures on the colon images, and then blood vessel extraction techniques were employed. Later, segmentation of the vessel boundaries was performed. With the help of vessel boundaries we calculated the vessel density, and used this for the localization of the polyps. We tested the success of this approach using a publicly available image set (CVC-ClinicDB database). This database consisted of 612 images from 29 different polyps. This approach succeeds in correct detection of 24 out of 29 different polyps. © 2019 Elsevier B.V., All rights reserved.Conference Object Hepatoselüler Karsinom Oluşumunda Etkili Moleküler Mekanizmaların İn Siliko Yöntemlerle Araştırılması(Institute of Electrical and Electronics Engineers Inc., 2020-09) Doǧan, Refika Sultan; Saka, Samed; Bakir-Güngör, Burcu; Gungor, Burcu BakirHepatocellular carcinoma (HCC) is the most common cause of cancer-related death in the world. The molecular changes in the organism during the development of HCC are not fully understood. The aim of the present study is to contribute to the identification of critical genes and pathways associated with HCC via integrating various bioinformatics methods. In this study, experiments were conducted on gene expression data of 14 HCC tissues and noncancerous control tissues. A total of 1229 genes, which show a statistically significant change between the groups, were identified. Among these, 681 genes were upregulated and 548 genes were downregulated. Via mapping the detected genes into protein protein interaction networks, active subnetwork search, subnetwork topological analysis and functional enrichment analyses were carried out. The interactions between the molecular pathways affected by HCC were also presented. © 2020 Elsevier B.V., All rights reserved.