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Scopus İndeksli Yayınlar Koleksiyonu

Permanent URI for this collectionhttps://hdl.handle.net/20.500.12573/395

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Author: search.filters.author.Dedeturk, Beyhan AdanurHas files: No

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  • Conference Object
    Comparison of Disease Specific Sub-Network Identification Programs
    (Institute of Electrical and Electronics Engineers Inc., 2018-09) Dedeturk, Beyhan Adanur; Bakir-Güngör, Burcu; Adanur, Beyhun; Gungor, Burcu Bakir
    Active sub-network search aims to identify a group of interconnected genes in a protein-protein interaction network that contains most of the disease-associated genes. In recent years, to address active sub-network search problem, various algorithms and programs are developed. In this study, performances of disease specific sub-network identification programs are compared. The same input dataset is run in jActiveModules, ActiveSubnetworkGA, CytoHubba, ClusterViz, MCODE, CytoMOBAS, PathFindR, PINBPA and PEWCC programs. Then, functional enrichment analysis is applied on obtained sub-networks. Finally, they are compared according to the results of GO Enrichment Analysis. In addition to these, work performances, features and requirements of programs are compared. © 2019 Elsevier B.V., All rights reserved.
  • Conference Object
    Citation - Scopus: 2
    Comparative Performance Analysis of Ethereum and Optimism Smart Contracts in Health Insurance
    (Institute of Electrical and Electronics Engineers Inc., 2024-10-26) Dedeturk, Beyhan Adanur; Dedeturk, Bilge Kagan
    One type of insurance that people purchase to cover unexpected medical expenses is health insurance. In exchange for premium payments, the insurance company may cover a portion of the insured person's medical expenses, such as prescription medications, hospital stays, and doctor visits. This method makes access to healthcare easier and less expensive. Health insurance systems do, however, have a number of issues, including fair insurance premium calculation, automation, data verification, privacy and security, and cost effectiveness. These issues are starting to be addressed by blockchain technology, particularly with the help of smart contracts. Using a comparison analysis between Ethereum and Optimism smart contracts, this paper demonstrates the performance of health insurance. Simulation of these BC technologies was carried out both on the Sepolia testnet and using Alchemy. Tools and metrics provided to monitor the performance of Alchemy applications, detect errors, and analyze user interactions were used in the measurements. While Ethereum's well-established ecosystem offers robust support for smart contracts, Optimism distinguishes itself as a scalable substitute that delivers quicker transaction speeds and more affordable options. According to the analysis results, the advantages and disadvantages of Ethereum and Optimism are highlighted when it comes to health insurance. © 2025 Elsevier B.V., All rights reserved.
  • Article
    Citation - Scopus: 6
    CSA-DE-LR Enhancing Cardiovascular Disease Diagnosis With a Novel Hybrid Machine Learning Approach
    (PeerJ Inc., 2024-07-18) Dedeturk, Beyhan Adanur; Dedeturk, Bilge Kagan; Bakir-Güngör, Burcu
    Cardiovascular diseases (CVD) are a leading cause of mortality globally, necessitating the development of efficient diagnostic tools. Machine learning (ML) and metaheuristic algorithms have become prevalent in addressing these challenges, providing promising solutions in medical diagnostics. However, traditional ML approaches often need to be improved in feature selection and optimization, leading to suboptimal performance in complex diagnostic tasks. To overcome these limitations, this study introduces a new hybrid method called CSA-DE-LR, which combines the clonal selection algorithm (CSA) and differential evolution (DE) with logistic regression. This integration is designed to optimize logistic regression weights efficiently for the accurate classification of CVD. The methodology employs three optimization strategies based on the F1 score, the Matthews correlation coefficient (MCC), and the mean absolute error (MAE). Extensive evaluations on benchmark datasets, namely Cleveland and Statlog, reveal that CSA-DELR outperforms state-of-the-art ML methods. In addition, generalization is evaluated using the Breast Cancer Wisconsin Original (WBCO) and Breast Cancer Wisconsin Diagnostic (WBCD) datasets. Significantly, the proposed model demonstrates superior efficacy compared to previous research studies in this domain. This study’s findings highlight the potential of hybrid machine learning approaches for improving diagnostic accuracy, offering a significant advancement in the fields of medical data analysis and CVD diagnosis. © 2024 Elsevier B.V., All rights reserved.
  • Article
    Citation - Scopus: 4
    Aguhyper: A Hyperledger-Based Electronic Health Record Management Framework
    (PeerJ Inc, 2024-05-22) Dedeturk, Beyhan Adanur; Bakir-Gungor, Burcu
    The increasing importance of healthcare records, particularly given the emergence of new diseases, emphasizes the need for secure electronic storage and dissemination. With these records dispersed across diverse healthcare entities, their physical maintenance proves to be excessively time-consuming. The prevalent management of electronic healthcare records (EHRs) presents inherent security vulnerabilities, including susceptibility to attacks and potential breaches orchestrated by malicious actors. To tackle these challenges, this article introduces AguHyper, a secure storage and sharing solution for EHRs built on a permissioned blockchain framework. AguHyper utilizes Hyperledger Fabric and the InterPlanetary Distributed File System (IPFS). Hyperledger Fabric establishes the blockchain network, while IPFS manages the off -chain storage of encrypted data, with hash values securely stored within the blockchain. Focusing on security, privacy, scalability, and data integrity, AguHyper ' s decentralized architecture eliminates single points of failure and ensures transparency for all network participants. The study develops a prototype to address gaps identi fi ed in prior research, providing insights into blockchain technology applications in healthcare. Detailed analyses of system architecture, AguHyper ' s implementation con fi gurations, and performance assessments with diverse datasets are provided. The experimental setup incorporates CouchDB and the Raft consensus mechanism, enabling a thorough comparison of system performance against existing studies in terms of throughput and latency. This contributes signi fi cantly to a comprehensive evaluation of the proposed solution and offers a unique perspective on existing literature in the fi eld.
  • Conference Object
    Citation - WoS: 4
    Citation - Scopus: 10
    Sağlıkta Blokzincir Tabanlı Sistem Bilişimi Uygulamaları
    (Institute of Electrical and Electronics Engineers Inc., 2020-10-05) Dedeturk, Beyhan Adanur; Bakir-Güngör, Burcu; Soran, Ahmet; Adanur, Beyhan
    Recently, the use of blockchain technology in the field of healthcare has increased. Although blockchain technology brought several innovations to healthcare, still there are problems waiting to be resolved. In order to provide alternative solutions to these problems, the use of fog computing together with blockchain technology has been proposed. In this study, the applications of blockchain based fog computing technology in healthcare are investigated. The aim of this study is to provide the readers an idea about the interactive use of blockchain and fog computing in the field of healthcare. For this purpose, firstly, fog computing and blockchain technologies are introduced. Afterwards, the integration of these areas, the advantages and disadvantages of using these technologies in the field of healthcare is discussed and a new system architecture is proposed. © 2021 Elsevier B.V., All rights reserved.