Scopus İndeksli Yayınlar Koleksiyonu
Permanent URI for this collectionhttps://hdl.handle.net/20.500.12573/395
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Article Citation - Scopus: 5University Librarians’ Perceptions Of Artificial Intelligence, Its Application Areas İn Libraries, And The Future(University and Research Librarians Association (UNAK), 2024-12-26) Cuhadar, S.; Mert, S.; Gezer, Ç.; Helvacioğlu, E.; Arus, O.; Aslan, Ö.; Atli, S.; Gurdal, Gultekin; Erken, MehmetToday, libraries are among the institutions affected by changing technology and innovations. The popularization of artificial intelligence (AI) technologies has also begun to transform library services. In this research, a survey was conducted to determine the adjustments that university libraries in Turkey have made and plan to make during the development process of AI technologies and applications, and to identify the services they have developed specific to the relevant period. The survey was carried out with the participation of 111 university library managers from 208 university libraries in Turkey. Through the analysis of the data, the status, knowledge, and awareness levels of university libraries regarding AI technologies and applications were determined, and measures and recommendations were presented to improve deficiencies and weaknesses. This research is the first and most comprehensive study conducted in Turkey by obtaining opinions and suggestions from university library managers on artificial intelligence. The research findings revealed that university libraries use AI applications such as ChatGPT, Gemini, and Grammarly to a certain extent; however, they have needs in developing institutional policies, enhancing personnel competencies, and planning related to AI. © 2024 University and Research Librarians Association (UNAK). All rights reserved.Article Performance Boost in QLEDs Using Octanethiol-Capped Core/Shell Quantum Dots(IOP Publishing Ltd, 2026-01-07) Yazici, Ahmet F.; Yuruc, Adnan M.; Kelestemur, Yusuf; Serin, Ramis Berkay; Kacar, Rifat; Ulku, Alper; Mutlugun, EvrenQuantum dots attract significant attention as one of the most promising colloidal nanocrystals with unique optical properties and potential applications for the next generation of display technology. In this paper, we evaluate the performance of CdZnSeS-based alloyed-shell quantum dots (QDs) for electroluminescence devices upon additional shell growth and ligand exchange. This includes core/shell (C/S) and core/shell/shell (C/S/S) QDs, whose latter includes an additional ZnS shell and octanethiol (OT) ligands. We present detailed characterizations of QDs using transmission electron microscopy, XRD, and various spectroscopic techniques and demonstrate their QD light emitting (QLEDs). We find the photoluminescence quantum yield of C/S/S QDs increased from 68.8% to 88.7% compared to C/S QDs whereas the emission linewidth narrows from 22.2 nm to 20.8 nm. QLEDs fabricated with C/S/S QDs exhibit a higher peak external quantum efficiency (EQE) of 4.1% and maximum luminance of 85 000 cd m-2, compared to 2.3% EQE and 67 000 cd m-2 for C/S QLEDs. In this respect, the OT-assisted shell growth significantly improves the optical property of QDs and performance of QLEDs, likely attributed to the enhanced charge balance and increased radiative recombination rate.Article A Small Indole Derivative Isolated From Caper (Capparis Ovata) as an Inducer of P53-Mediated Apoptosis in Prostate Cancer: Comprehensive In Vitro and In Silico Studies(Wiley, 2025-12-31) Acar, Ozden Ozgun; Gazioglu, Isil; Oruc, Hatice; Kale, Elif; Senol, Halil; Topcu, Gulacti; Sen, AlaattinNatural products with stunning chemical diversity have been extensively researched for their anticancer potential for more than fifty years. This study aimed to determine the effect of indole derivative 1H-indole-2-hydroxy-3-carboxylic acid (IHCA), isolated as a novel alkaloid from Capparis ovata, on selected tumor suppressor, apoptotic, and cell cycle regulatory genes, which are known to be important in cancer pathophysiology, on Caco-2 and LNCaP cells in comparison with Taxol. The molecular mechanism of IHCA's anticancer activity is essentially undefined. Different concentrations of IHCA increased the expression levels of apoptosis-related genes, including BCL-2 and TNF-alpha. In addition, the tumor suppressor genes PTEN, P53, and RB were increased in LNCaP and Caco-2 cells. KRAS, an oncogenic gene, was significantly downregulated by IHCA in LNCaP cells. Western blot results showed that the protein expression levels of P53 and PTEN in LNCaP cells were increased when treated with IHCA, whereas CDK4 and TNF-alpha were decreased. Finally, IHCA and doxorubicin significantly increased P53-driven luciferase activity compared to the control. The results strongly suggest that the novel natural compound IHCA has an anticancer effect involving the regulation of the P53 gene and its networks in vitro. The molecular docking and MD simulation analyses reveal that IHCA exhibits superior binding potential to the MDM2 protein compared to Nutlin-3a. MD simulations further confirm that IHCA maintains a more stable and consistent interaction with MDM2, as indicated by lower RMSD values and reduced ligand fluctuation. These results highlight IHCA's potential as a more effective MDM2 inhibitor, suggesting its promise as a lead compound for anticancer drug development.Clinical Trial Registration: Not applicable.Editorial Advances in Natural Building and Construction Materials(MDPI, 2025-12-16) Strzalkowski, Pawel; Sousa, Luis; Koken, Ekin; Strzałkowski, PawełArticle G-S a Prior Biological Knowledge-Based Pattern Detection and Enrichment Framework for Multi-Omics Data Integration(MDPI, 2025-11-29) Unlu Yazici, Miray; Bakir-Gungor, Burcu; Yousef, MalikThe rapid advancements in high-throughput technologies have led to a dramatic increase in diverse -omics data types, enabling comprehensive analyses, especially for complex diseases like cancer. Despite the development of multi-omics approaches, the challenges of scaling integration to massive, heterogeneous -omics datasets suggest that novel computational tools need to be designed. In this study, we propose an approach for integrating microRNA (miRNA) and messenger RNA (mRNA) expression data, incorporating prior biological knowledge (PBK). This approach scores and ranks groups of miRNAs and their associated genes using cross-validation iterations. The proposed method incorporates a Pattern detection (P) component to identify molecular motifs unique to each biological group. The analysis also facilitates the visualization of the groups, facilitating the identification of co-occurring groups and their characteristic features across iterations. Furthermore, the groups are scored using an over-representation analysis through a new Enrichment (E) component in each iteration. The clusters of the groups based on the Enrichment Scores (ESs) are visualized in a heatmap to obtain novel insights into the collective behavior and dependencies of the groups, aiming to understand the molecular mechanisms of complex diseases. The developed G-S-M-E tool not only provides performance metrics and biological scores at the group level but also offers comprehensive insights into intricate multi-omics interactions. In summary, our study emphasizes the importance of mathematical and data science methodologies in elucidating intricate multi-omics integration, yielding a formalized approach that deepens our comprehension of complex diseases.Article Assessment of the Quality of Tuffs in Central Anatolia, Turkey: A Quantitative Classification Approach(Acad Sci Czech Republic Inst Rock Structure & Mechanics, 2025-12-03) Koken, Ekin; Ince, IsmailThe growing global demand for dimension stones necessitates efficient and accurate evaluation methods to ensure their optimal use in various industries. To assess their suitability for various dimension stone applications, this study investigates tuffs from Central Anatolia, Turkey. For this purpose, the fundamental physical and mechanical properties of the tuffs were determined in laboratory studies, and a detailed durability assessment was conducted for each rock type. The analysis results indicate that most of the examined rocks are of low quality and more suitable for non-load-bearing applications. Based on the collected data, fuzzy clustering techniques were applied to develop a new classification system, categorising the tuffs into four classes (Class A-D) according to their potential applications. Additionally, a user-friendly MATLAB-based software tool was also developed to facilitate the implementation of the proposed classification system.Article Measuring Disaster Resilience in MENA Countries and Its Impact on Disaster Losses(Nature Portfolio, 2025-12-08) Demir, Abdullah; Dincer, Ali Ersin; Dincer, Nazire NergizDisaster resilience is a protective feature aimed at reducing the effects of natural disaster events and losses resulting from these events. This study develops a Disaster Resilience Index (DRI) for MENA countries to assess resilience across ten dimensions, including economic, social, institutional, infrastructural, and environmental factors. Unlike most prior studies, which focus on individual countries or use narrower sets of indicators, this study provides a multi-country, region-specific framework tailored to MENA's socio-economic and environmental heterogeneity. The index integrates geospatial data on disaster risk from geographic information systems (GIS) and a natural hazard risk dimension. Validation using disaster-related fatalities, supported by a dual PCA-based sensitivity analysis, confirms the robustness of the DRI and reveals that countries with stronger governance, higher human capital, and robust infrastructure tend to exhibit greater resilience, while fragile states and resource-dependent economies are more vulnerable. Notably, the DRI calculated using both dimension-specific and all-indicator PCA produces closely aligned values, indicating the choice of conducting PCA at the dimension level does not significantly alter the overall assessment of disaster resilience. These insights provide a foundation for targeted disaster risk reduction strategies and highlight areas where international cooperation and policy interventions can strengthen resilience in the region.Conference Object Clean Energy Production and Decarbonization of Energy Sector With Floating Photovoltaic Systems(Institute of Physics, 2025-11-01) Bajc, T.; Ozgun, F.; Koca, K.; Karipoğlu, F.Floating photovoltaic systems (FPVS) offer several advantages over traditional land-based PV systems, which has contributed to a growing global interest in their deployment. Since the energy yields are strongly dependent on location and tilt angle of FPVS, this research focuses on the clean energy production and decarbonization potential of FPVS in Serbia and Türkiye for different water bodies, such are natural and artificial lakes and dams. The research is performed for the most appropriate lakes and dams, having in mind importance of the location, energy yields potential, distance from the electricity grid and main roads, environmental impact, water depth and land type quality. Tilt angles are analyzed in a range from 5 to 40°, and the optimal angle is depicted for selected locations. The highest energy yields for Türkiye were obtained for 30° tilt angle, while for Serbia it was 36°. The results showed that possible clean energy production in both countries reaches 15345 kWh of energy in total, while the yearly carbon emissions reduction for all selected locations goes up to 10.76 tCO<inf>2</inf>/year in total. Since the legal framework for the application of FPVS is not established yet in observed countries, these results contribute to the future development of legislation in the field of FPVS and encourage the stakeholders to invest in clean energy production. © Published under licence by IOP Publishing Ltd.Conference Object Offshore Floating Modular Energy Islands: Technologies and Challenges(Institute of Physics, 2025-11-01) Gkantou, M.; Amlashi, H.; Snæbjörnsson, J.; Skejic, D.; Ferri, G.; Marino, E.; Baniotopoulos, C.Offshore floating modular energy islands (FMEIs) represent a promising solution to meet growing global energy demands, while addressing challenges associated with conventional energy infrastructure. This paper explores key technological components underpinning the design, construction, and energy generation of FMEIs, with a focus on three core areas: energy generation systems, floating structures and construction methods. The first technological component focuses on energy generation systems, examining the technologies of offshore wind power, solar and wave energy, to maximise overall energy production, while also highlighting the challenges involved in integrating these technologies. The second section examines the support structure of offshore floating platforms, as well as the key role of mooring systems in ensuring structural integrity under challenging marine conditions. The importance of advanced monitoring and maintenance strategies for long-term viability is also discussed. The third technological component discusses modular construction, highlighting the material choices and associated construction challenges in building FMEIs. This review also includes case studies and ongoing projects that demonstrate the real-world application of these technologies. Through the integration of advanced renewable energy generation technologies, floating and mooring systems and modular construction methods, FMEIs offer a sustainable and innovative approach to offshore energy production. This paper provides an overview of FMEIs and contributes to advancing development in this emerging field. © Published under licence by IOP Publishing Ltd.Conference Object Modular Floating Energy Islands With Green Hydrogen Integration: Design of a Small-Scale P2x Scheme(Institute of Physics, 2025-11-01) Akpolat, A.N.; Cundeva, S.; Todorovic, J.; Rexhepi, V.; Okhay, O.; Bakon, T.; Borg, R.P.The climate crisis and rising carbon emissions make the integration of renewable energy systems into electricity grids worldwide inevitable. In this context, modular floating energy islands (MFEI) provide innovative solutions for hybrid systems with high renewable energy penetration. This study explores the simultaneous use of various renewable resources, such as solar, wind, tidal, and wave energy, through small-scale MFEI structures that can be situated in seas and lakes. Thanks to their modular design, these systems offer benefits like scalability, portability, and ease of maintenance, allowing for flexible and adaptive developments in the energy infrastructure. As highlighted in recent literature (e.g., the North Sea Wind Power Hub and EU H2Ocean projects), offshore structures for green hydrogen production support energy storage and carbon-free fuel conversion within the Power-to-X (P2X) framework. This study evaluates the potential of photovoltaic (PV)-supported hydrogen production in MFEI structures through numerical analyses. The results emphasize the strategic role of these structures in enhancing energy security, coastal protection, and reducing carbon emissions by producing significant amounts of hydrogen. This hydrogen can be used for various purposes, including re-electrification, industrial applications, heating, and agriculture. Future research should focus on real-time data optimization, AI-supported system management, and integrated hydrogen consumption scenarios. © Published under licence by IOP Publishing Ltd.