Scopus İndeksli Yayınlar Koleksiyonu
Permanent URI for this collectionhttps://hdl.handle.net/20.500.12573/395
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Conference Object Citation - Scopus: 2miRcorrNetPro: Unraveling Algorithmic Insights Through Cross-Validation in Multi-Omics Integration for Comprehensive Data Analysis(Institute of Electrical and Electronics Engineers Inc., 2023-12-05) Ünlü Yazici, Miray; Yousef, Malik; Marron, J. S.; Bakir-Güngör, Burcu; Yazici, Miray UnluHigh throughput -omics technologies facilitate the investigation of regulatory mechanisms of complex diseases. Along this line, scientists develop promising tools and methods to extend our understanding at the molecular and functional levels. To this end, miRcorrNet tool performs integrative analysis of MicroRNA (miRNA) and gene expression profiles via machine learning (ML) approach to identify significant miRNA groups and their associated target genes. In this study, we propose miRcorrNetPro tool, which extends miRcorrNet by tracking group scoring, ranking and other information through the cross-validation iterations. Heatmap visualizations enable deep novel insights into the collective behavior of clusters of groups in cellular signaling and hence facilitate detection of potential biomarkers for the disease under investigation. Although miRcorrNetPro is designed as a generic tool, here we present our findings and potential miRNA biomarkers for Breast Cancer (BRCA). The miRcorrNetPro tool and all other supplementary files are available at https://github.com/Miray-Unlu/miRcorrNetPro. © 2024 Elsevier B.V., All rights reserved.Conference Object Citation - Scopus: 1Words Speak Louder Than Actions: Decoding Emotions Through NLP(Institute of Electrical and Electronics Engineers Inc., 2024-10-26) Paksoy, Melda; Bakal, GokhanEmotion detection in text remains a significant challenge in Natural Language Processing due to human emotions' complexity and subtle nuances. This paper presents multiple experimental models for emotion classification using an up-to-date dataset curated to address 13 emotions implied in Twitter posts. We evaluated various machine learning (ML) models, including Logistic Regression, Random Forest, SVM, and XGBoost, alongside deep learning (DL) architectures such as LSTM and CNN. Our results demonstrate the efficacy of deep learning models, particularly the CNN model by achieving an impressive F1 score of 0.99. This study contributes to emotion detection capabilities, paving the way for more nuanced and accurate sentiment analysis (SA) in various text analysis applications. © 2025 Elsevier B.V., All rights reserved.Conference Object Citation - Scopus: 1TextNetTopics_TIS: Enhancing Textnettopics With Random Forest-Based Topic Importance Scoring(Institute of Electrical and Electronics Engineers Inc., 2024-10-16) Voskergian, Daniel; Bakir-Güngör, Burcu; Yousef, MalikTextNetTopics is an innovative Latent Dirichlet Allocation-based topic selection method for training text classification models. One main limitation is its computationally intensive scoring mechanism, especially when applied to many topics. This scoring mechanism involves training a machine learning model (i.e., Random Forest) on each topic using the Monte-Carlo Cross-Validation approach and assigning a score value based on a specific performance metric (e.g., accuracy or F1-score). Moreover, the measured score does not account for the interactions between all features residing in all topics. This paper presents a new topic-scoring mechanism called Topic Importance Scoring. This computationally efficient approach trains a Random Forest model on all topics simultaneously and leverages the extracted feature importance values to give each topic a score reflecting its classification potential. The experiments on three diverse datasets confirm that the proposed method's performance is superior to the Topic Performance Scoring, which was used in the original TextNetTopics method. © 2024 Elsevier B.V., All rights reserved.Article Citation - Scopus: 2Prediction of Colorectal Cancer Based on Taxonomic Levels of Microorganisms and Discovery of Taxonomic Biomarkers Using the Grouping-Scoring (G-S-M) Approach(Elsevier Ltd, 2025-03) Bakir-Güngör, Burcu; Temiz, Mustafa; Canakcimaksutoglu, Beyza; Yousef, MalikColorectal cancer (CRC) is one of the most prevalent forms of cancer globally. The human gut microbiome plays an important role in the development of CRC and serves as a biomarker for early detection and treatment. This research effort focuses on the identification of potential taxonomic biomarkers of CRC using a grouping-based feature selection method. Additionally, this study investigates the effect of incorporating biological domain knowledge into the feature selection process while identifying CRC-associated microorganisms. Conventional feature selection techniques often fail to leverage existing biological knowledge during metagenomic data analysis. To address this gap, we propose taxonomy-based Grouping Scoring Modeling (G-S-M) method that integrates biological domain knowledge into feature grouping and selection. In this study, using metagenomic data related to CRC, classification is performed at three taxonomic levels (genus, family and order). The MetaPhlAn tool is employed to determine the relative abundance values of species in each sample. Comparative performance analyses involve six feature selection methods and four classification algorithms. When experimented on two CRC associated metagenomics datasets, the highest performance metric, yielding an AUC of 0.90, is observed at the genus taxonomic level. At this level, 7 out of top 10 groups (Parvimonas, Peptostreptococcus, Fusobacterium, Gemella, Streptococcus, Porphyromonas and Solobacterium) were commonly identified for both datasets. Moreover, the identified microorganisms at genus, family, and order levels are thoroughly discussed via refering to CRC-related metagenomic literature. This study not only contributes to our understanding of CRC development, but also highlights the applicability of taxonomy-based G-S-M method in tackling various diseases. © 2025 Elsevier B.V., All rights reserved.Conference Object Metabolomics Data Analysis to Discover Chronic Granulomatous Disease-Associated Biomarkers Utilizing G-S-M Machine Learning Model via Grouping Metabolites According to Ion Type(Institute of Electrical and Electronics Engineers Inc., 2024-10-16) Ersöz, Nur Sebnem; Bakir-Güngör, Burcu; Yousef, MalikChronic Granulomatous Disease (CGD) is a rare, inherited immunodeficiency disorder characterized by white blood cells unable to effectively kill certain bacteria and fungi. This defect results in the formation of clusters of immune cells called granulomas that form at sites of infection or inflammation. Therefore, identification of disease-related biomarkers is a critical step in advancing precision medicine and improving diagnostic accuracy. In this study, we applied a G-S-M machine learning approach to metabolomics data to uncover CGD-Associated biomarkers. We obtained a metabolomics dataset from Gene Expression Omnibus with GSE220260 accession number. Data includes 85 samples (16 healthy controls and 69 CGD samples) with comprehensive metabolic profiles obtained using liquid chromatography-mass spectrometry analysis. Dataset includes metabolite names with their ion type and formula. In order to identify CGD related metabolites and their ion types, G-S-M was used as a grouping function when performing machine learning oriented metabolomics data analysis. We have performed the G-S-M approach by grouping metabolites according to their ion type. In the training part of the G-S-M approach, metabolites annotated with selected ion types have been utilized to perform a two-class classification task which generates an important set of ion type output. We also compared the performance results of the G-S-M machine learning model with traditional feature selection methods; XGB, SKB, IG, FCBF, MRMR, CMIM with random forest classifier. 100 times Monte-Carlo Cross Validation was used in our experiments. It was observed that G-S-M, XGB, SKB and FCBF methods similarly provided the best performances. In this study, besides its performance, G-S-M method used groups based on ion types unlike TFS, and then identified relevant Chronic Granulomatous Disease-associated metabolites. © 2024 Elsevier B.V., All rights reserved.Conference Object Linear Vs. Non-Linear Embedding Methods in Recommendation Systems(Institute of Electrical and Electronics Engineers Inc., 2022-09-07) Gurler, Kerem; Cos¸kun, Mustafa; Karagenc, Safak; Orun, Gokhan; Kuleli Pak, Burcu Kuleli; Güngör, Vehbi Çağrı; Coskun, Mustafa; Pak, Burcu KuleliPredicting customer interest in items is very crucial in direct marketing as it can potentially boost sales. Data mining techniques are developed to predict which items a particular user might be interested in based on their purchase history or explicit feedback in form of ratings or comments. Recently, non-linear and linear methods have been developed for this purpose. In this study, we applied Neighborhood based Collaborative Filtering (CF), Matrix Factorization (MF), Singular Value Decomposition (SVD), Neural Graph CF (NGCF) and Light Graph Convolutional Network (LightGCN) on explicit user product rating data which is acquired from the online gaming and mobile entertainment platform called HADI. We compared the results of node embedding methods in terms of Precision@k, Recall@k and NDCG@k values. SVD and LightGCN showed the best test performance and SVD was significantly superior to LightGCN in terms of training speed. To further increase predictive performance of SVD, we have applied classification with Logistic Regression and Deep Random Forest on user and item embeddings created by the SVD. © 2022 Elsevier B.V., All rights reserved.Conference Object Citation - Scopus: 1Improving Salary Offer Processes With Classification Based Machine Learning Models(Institute of Electrical and Electronics Engineers Inc., 2024-09-21) Kaya, Rukiye; Saatci, Mehtap; Bakal, Gokhan; Bakal, Mehmet GokhanIn job applications, salary is major motivational factor for employees and making accurate salary prediction is crucial for both employers and employees. Utilizing advanced technologies can significantly enhance the accuracy and efficiency of salary prediction process. In this study, we explore Machine Learning (ML) methods to enhance salary prediction process. We evaluated seven classification models for predicting salary categories, with the Artificial Neural Network (ANN) model achieving the highest accuracy at 58.2% on the test dataset, followed by the K-Nearest Neighbors (KNN) model with an accuracy of 56.8%. Additionally, we employed ensemble models to further enhance prediction accuracy. Among these, the Majority Voting Classifier using Hard Voting achieved the highest accuracy at 59.3%, demonstrating the potential of ensemble techniques in refining salary predictions. The developed salary prediction tool estimates the most appropriate salary category for each candidate and help mitigate potential biases in manual salary assessments, hence enables a more objective and consistent compensation system. ∗CRITICAL: Do Not Use Symbols, Special Characters, or Math in Paper Title or Abstract, and do not cite other papers in the abstract. © 2024 Elsevier B.V., All rights reserved.Conference Object Citation - Scopus: 1From Traditional to Deep: Evaluating Sentiment Analysis Models on a Large-Scale Tweet Dataset(Institute of Electrical and Electronics Engineers Inc., 2024-10-26) Mammadov, Alisahib; Bakal, GokhanThis study investigates the effectiveness of various machine learning (ML) and deep learning (DL) techniques for large-scale sentiment analysis on Twitter data. We leverage a publicly available dataset of one million tweets, annotated with four sentiment labels (positive, negative, uncertainty, and liti-gious), to train and evaluate a range of models. Our experiments demonstrate that traditional ML algorithms, particularly XG-Boost, achieve high performance, with the best F1 score reaching 95.81% using a combination of unigrams and bigrams. Among DL models, a hybrid CNN-BiGRU architecture yields the highest average F1 score of 95.42%. Our findings highlight the strengths of different approaches for sentiment analysis on Twitter data and emphasize the importance of data preprocessing and model selection for achieving optimal performance. © 2025 Elsevier B.V., All rights reserved.Conference Object Evaluating the Impact of Sentiment Analysis on Deep Reinforcement Learning-Based Trading Strategies(Institute of Electrical and Electronics Engineers Inc., 2024-10-26) Etcil, Mustafa; Kolukisa, Burak; Bakir-Güngör, BurcuPortfolio optimization is a form of investment management that aims to maximize returns while minimizing risks. However, the inherent complexity and unpredictability of financial markets pose a challenge. Recent advancements in machine learning, particularly in deep reinforcement learning (DRL), offer promising solutions by enabling dynamic and adaptive trading strategies. This paper presents a comprehensive evaluation of three actor-critic-based DRL algorithms-Advantage Actor-Critic (A2C), Deep Deterministic Policy Gradient (DDPG), and Proximal Policy Optimization (PPO)-applied to portfolio optimization. These strategies were implemented in both sentiment-aware and non-sentiment-aware versions, allowing for a direct comparison of their performance. The sentiment-aware models incorporated sentiment analysis using FinBERT and knowledge graphs to measure market sentiment from financial news, while the non-sentiment-aware models relied solely on stock prices and technical indicators. Our comparative study demonstrates that incorporating sentiment analysis resulted in consistently superior risk-adjusted returns and portfolio resilience during market fluctuations compared to non-sentiment-aware strategies. © 2025 Elsevier B.V., All rights reserved.Conference Object Citation - Scopus: 2Data-Driven Methods for Optimal Setting of Legacy Control Devices in Distribution Grids(IEEE Computer Society, 2024-07-21) Savasci, Alper; Ceylan, Oǧuzhan; Paudyal, SumitThis study presents machine learning-based dispatch strategies for legacy voltage regulation devices, i.e., onload tap changers (OLTCs), step-voltage regulators (SVRs), and switched-capacitors (SCs) in modern distribution networks. The proposed approach utilizes k-nearest neighbor (KNN), random forest (RF), and neural networks (NN) to map nodal net active and reactive injections to the optimal legacy controls and resulting voltage magnitudes. To implement these strategies, first, an efficient optimal power flow (OPF) is formulated as a mixed-integer linear program that obtains optimal decisions of tap positions for OLTCs, SVRs, and on/off status of SCs. Then, training and testing datasets are generated by solving the OPF model for daily horizons with 1-hr resolution for varying loading and photovoltaic (PV) generation profile. Case studies on the 33-node feeder demonstrate high-accuracy mapping between the input feature and the output vector, which is promising for integrated Volt/VAr control schemes. © 2024 Elsevier B.V., All rights reserved.