WoS İndeksli Yayınlar Koleksiyonu
Permanent URI for this collectionhttps://hdl.handle.net/20.500.12573/394
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Article Vim-Polyp: Multimodal Colon Polyp Dataset with Video, Histopathology, and Protein Expression(Nature Portfolio, 2025-12-03) Dogan, Refika Sultan; Akay, Ebru; Dogan, Serkan; Yilmaz, BulentThe dataset in this study includes 202 videos with a total of 422 minutes, reaching Kayseri City Hospital's gastroenterology department as colonoscopy videos and 1903 microscopy images between 2019 and 2021. It includes 399 colonoscopy, microscopy images, and pathological diagnoses of polyps, as well as immunohistochemical staining results for proteins that play an important role in the assessment of cancerous cells, such as staining results for p53 (clone: bp53-11), Ki-67 (clone: 30-9), CD34 (clone: QBend/10), PD-L1 (clone: SP142), BRAF (clone: V600E) and VEGF (clone: SP125). By sharing the data openly, we aim to facilitate benchmarking, exploratory analysis and transfer-learning studies on colorectal polyps and cancer. In combination with external datasets or pretrained models, the resource can help advance data-driven detection and characterisation work. The diverse range of polyps assigned to cancer stages from 201 patients makes this tool valuable for researchers and clinicians in furthering diagnosis and treatment.Conference Object Real-Time Robotic Car Control Using Brainwaves and Head Movement(IEEE, 345 E 47TH ST, NEW YORK, NY 10017 USA, 2018) Ozturk, Nedime; Yilmaz, Bulent; Onver, Ahmet YasinEmotiv Epoc Headset is a portable and low-cost device. In this study, Emotiv Epoc headset was used in order to obtain real-time gyro and EEG signals. The aim of this study was to control a robotic car in real-time by using head movement and opening and closing of the eyes. The maximum and minimum amplitude of the gyro signal, and the ratios of the beta waves of O1 and O2 channel to alpha waves of the same channels were used as threshold values. These threshold values were used to determine the direction of the robotic car. Because of its low-cost and easy implementation, Arduino Uno was used to manage the robotic car. This study has shown that brain waves and head movements can control a device in real time. This system has the potential to be used in neurofeedback and brain-computer interface applications.Conference Object Effect of Bilinear Interpolation on the Texture Analysis of Colonoscopy Images(IEEE345 E 47TH ST, NEW YORK, NY 10017 USA, 2017) Kacmaz, Rukiye Nur; Yilmaz, BulentInterpolation is a method that is used to obtain unknown intensities with the help of known intensities on an image. This method is frequently used in the literature to eliminate light reflection on colonoscopy images. Texture features are the most important characteristics used to describe the region or objects of interest in the image. They are the measures of intensity variation of a surface that determine properties such as smoothness, roughness, and regularity. The aim of this study is to find out the how bilinear interpolation applied on colonoscopy images with reflection impact texture features obtained from the same images. A research carried out to make reasonable comparison between a texture feature from an image with no reflection and the same feature obtained from the same image with synthetically added reflections with various percentages. Using the approaches like gray level co-occurence matrix (GLCM), gray level run length matrix (GLRLM), neighborhood gray tone difference matrix (NGTDM) 126 features were extracted from each 32x32 sub-images coming from 610 colonoscopy images. Several of the features extracted from sub-images with no reflection and reflection were not statistically significantly different, while majority of them were affected from the reflections.Conference Object Detection of Variation Instances on Colonoscopy Videos using Structural Similarity Index(IEEE, 345 E 47TH ST, NEW YORK, NY 10017 USA, 2018) Kacmaz, Rukiye Nur; Yilmaz, BulentThe aim of this study is to reduce the number of images extracted from the videos recorded by the specialists during the colonoscopy process for further examination, thereby enabling the specialist to deal with fewer images. Since the images obtained from the videos are very similar, the main assumption of this study is that the whole video can be represented by fewer images. The approach used in this study is the structural similarity index. Totally, images were obtained from 4 different videos coming from healthy, ulcerative colitis, Crohn's, and polyp patients. The noisy images in these videos were eliminated manually. When the structural similarity index between two consecutive clear images was less than 0.83, the second image was selected and shown to the specialist for his/her examination. By this way, the frames carrying significantly new information from the videos were defined as the variation instances. The tests on healthy or diseased colon videos showed that only 5-10% of the clear images provide significantly new information.Article Use of Laser-Induced Bubbles in Intraocular Pressure Measurement: A Preliminary Study(IOP Publishing Ltd, 2018-11-23) Altindis, Fatih; Ozdur, Ibrahim T.; Mutlu, Sait N.; Yilmaz, BulentThis work investigates the feasibility of a novel approach for measuring intraocular pressure (IOP) by analyzing micron-level laser-induced bubble characteristics in the intraocular fluid. We believe that this concept may be used as a non-invasive alternative for measuring a patient's IOP by analyzing the laser-induced bubble volume in the intraocular fluid in the anterior chamber of the eye. The behavior of laser-induced bubbles was examined under differing fluid pressure levels and at differing laser pulse energy levels. An intraocular medium-like environment was imitated and an imaging system was designed in order to capture laser-induced bubbles with their movements. The video recordings of the bubbles were processed using custom software, and the volume of the bubbles was estimated using three different approaches. The bubble volumes were estimated more accurately by using the rising velocity of the bubble rather than its direct radii appearances on the images. An inversely proportional relationship was observed between the laser-induced bubble volume and the fluid pressure. IOP can be measured with a non-invasive technique using laser-induced bubble volume. Deeper and detailed studies, including clinical studies, may lead to the use of lasers for measuring IOP.Conference Object Citation - WoS: 7Citation - Scopus: 12Use of Topological Data Analysis in Motor Intention Based Brain-Computer Interfaces(European Signal Processing Conference, EUSIPCO, 2018-09) Altindis, Fatih; Yilmaz, Bulent; İçöz, Kutay; Borisenok, S.This study aims to investigate the use of topological data analysis in electroencephalography (EEG) based on brain-computer interface (BCI) applications. Our study focused on extracting topological features of EEG signals obtained from the motor cortex area of the brain. EEG signals from 8 subjects were used for forming data point clouds with a real-time simulation scenario and then each cloud was processed with JPlex toolbox in order to find out corresponding Betti numbers. These numbers represent the topological structure of the point data cloud related to the persistent homologies, which differ for different motor activity tasks. The estimated Betti numbers has been used as features in k-NN classifier to discriminate left or right hand motor intentions. © 2019 Elsevier B.V., All rights reserved.Article Citation - WoS: 5Citation - Scopus: 6Transfer Learning for P300 Brain-Computer Interfaces by Joint Alignment of Feature Vectors(IEEE-Inst Electrical Electronics Engineers Inc, 2023-10) Altindis, Fatih; Banerjee, Antara; Phlypo, Ronald; Yilmaz, Bulent; Congedo, MarcoThis article presents a new transfer learning method named group learning, that jointly aligns multiple domains (many-to-many) and an extension named fast alignment that aligns any further domain to previously aligned group of domains (many-to-one). The proposed group alignment algorithm (GALIA) is evaluated on brain-computer interface (BCI) data and optimal hyper-parameter values of the algorithm are studied for classification performance and computational cost. Six publicly available P300 databases comprising 333 sessions from 177 subjects are used. As compared to the conventional subject-specific train/test pipeline, both group learning and fast alignment significantly improve the classification accuracy except for the database with clinical subjects (average improvement: 2.12 +/- 1.88%). GALIA utilizes cyclic approximate joint diagonalization (AJD) to find a set of linear transformations, one for each domain, jointly aligning the feature vectors of all domains. Group learning achieves a many-to-many transfer learning without compromising the classification performance on non-clinical BCI data. Fast alignment further extends the group learning for any unseen domains, allowing a many-to-one transfer learning with the same properties. The former method creates a single machine learning model using data from previous subjects and/or sessions, whereas the latter exploits the trained model for an unseen domain requiring no further training of the classifier.Article Citation - WoS: 56Citation - Scopus: 69Synchrosqueezing Transform Based Feature Extraction From EEG Signals for Emotional State Prediction(Elsevier Sci Ltd, 2019-07) Ozel, Pinar; Akan, Aydin; Yilmaz, BulentThis paper presents a novel method for emotion recognition based on time-frequency analysis using multivariate synchrosqueezing transform (MSST) of multichannel electroencephalography (EEG) signals. With the advancements of the multichannel sensor applications, the need for multivariate algorithms has become obvious for extracting features that stem from multichannel dependency in addition to mono-channel features. In order to model the joint oscillatory structure of these multichannel signals, MSST has recently been proposed. It uses the concepts of joint instantaneous frequency and bandwidth. Electrophysiological data processing mostly requires joint time-frequency analysis in addition to both time and frequency analysis separately. The short-time Fourier transform (STFT) and wavelet transform (WT) are the main approaches utilized in time-frequency analysis. In this paper, the feasibility and performance of multivariate wavelet-based synchrosqueezing algorithm was demonstrated on EEG signals obtained from publically available DEAP database by comparing with its univariate version. Eight emotional states were considered by combining arousal-valence and dominance dimensions. Using linear support vector machines (SVM) as a classifier, MSST and its univariate version resulted in the highest prediction accuracy rates of (9) over tilde3% among all emotional states. (C) 2019 Elsevier Ltd. All rights reserved.Article Citation - WoS: 27Citation - Scopus: 30Super Resolution Convolutional Neural Network Based Pre-Processing for Automatic Polyp Detection in Colonoscopy Images(Pergamon-Elsevier Science Ltd, 2021-03) Tas, Merve; Yilmaz, BulentColonoscopy is the most common methodology used to detect polyps on the colon surface. Increasing the image resolution has the potential to improve the automatic colonoscopy based diagnosis and polyp detection and localization. In this study, we proposed a pre-processing approach that uses convolutional neural network based super resolution method (SRCNN) to increase the resolution of the training colonoscopy images before the localization of polyps. We also investigated the use of CNN based models such as the Single Shot MultiBox Detector (SSD) and Faster Regional CNN (RCNN) for real-time polyp detection and localization. Our results showed that using SRCNN method before the training process provides better results in terms of accuracy in both models compared to the low-resolution cases. Furthermore, we reached an F2 score of 0.945 for the correct localization of colon polyps using Faster RCNN with ResNet-101 feature extractor.Article Citation - WoS: 7Citation - Scopus: 9Split-Attention Effects in Multimedia Learning Environments: Eye-Tracking and EEG Analysis(Springer, 2022-02-02) Mutlu-Bayraktar, Duygu; Ozel, Pinar; Altindis, Fatih; Yilmaz, BulentThis study aimed to evaluate the split-attention effect in multimedia learning environments via objective measurements as EEG and eye-tracking. Two different multimedia learning environments in a focused (integrated) and split-attention (separated) format were designed. The experimental design method was used. The participants consisted of 44 students divided into two groups for focused attention and split-attention. There were significant differences between the fixation, brain wave, and retention performance of the two groups. Fixations of the split-attention group were higher than the focused attention group. A significant difference was found in the focused attention group in the alpha brain wave in the frontal region for intra-group comparisons and in the split-attention group in the beta brain wave in the frontal area for the inter-group comparison. The retention performance of the focused attention group was higher than the split-attention group. Accordingly, more cognitive activity emerged in environments where the text was not integrated into the picture. Additionally, the narration of text instead of printed text is effective for focusing attention. To prevent the emergence of a split-attention effect, the text should be integrated into the picture in designs. Due to the split-attention effect, the eye-tracking and EEG data were different between the groups.
