TR-Dizin İndeksli Yayınlar Koleksiyonu
Permanent URI for this collectionhttps://hdl.handle.net/20.500.12573/396
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Article Citation - Scopus: 2Zeolite Synthesis by Alkali Fusion Method Using Two Different Fly Ashes Derived From Turkish Thermal Power Plants(Chamber of Mining Engineers of Turkey, 2020-03-01) Top, S.; Vapur, HüseyinIn this study, Faujasite (Na-LSX) (3.5(Ca0.3)3.5(Na0.6)3.5(Mg0.1)Al7Si17O48 32(H2O)) type zeolites and Ca-Filipsite (CaK0.6Na0.4Si5.2Al2.8O16 6(H2O)) type zeolites were produced from Sugözü Thermal Power Plant and Çatalaǧzi Thermal Power Plant fly ashes by alkali fusion method followed by water leaching, respectively. In these methods, fly ashes and sodium hydroxide (NaOH) were mixed in certain proportions and sintered at 600°C in ash furnace. Then, zeolites were obtained from the ground materials after water leaching and solid/liquid separation, respectively. Cation Exchange Capacity (CEC), X-Ray Diffraction (XRD), Scanning Electron Microscopy (SEM), Fourier-Transform Infrared Spectroscopy (FTIR), X-Ray Fluorescence (XRF) and Atomic Absorption Spectrometer (AAS) analyses were used to characterize the synthesized zeolites. The zeolites synthesized with Sugözü fly ashes in a ratio of 1:2 had 136.93 meq/100 g CEC, whereas the CEC of synthesized zeolite from Çatalaǧzi fly ashes was found to be 247.88 meq/100 g. As a result, zeolites, which can be used as wastewater treatment agent, energy storage material, catalyst and separator, were synthesized by using 2 different Class F fly ash. © 2023 Elsevier B.V., All rights reserved.Article Tracing Trajectories of Regime Support in Turkey(Ege Univ, Fac Economics & Admin Sciences, 2022-06-09) Inan, MuratAccording to the legitimacy approach of political culture research, public's approval of a particular regime as the best form of government and rejection of its alternatives provides public support for that particular regime. This research attempted to trace temporal trajectories of approval of democratic political system as well as it's three alternative forms of government among the electorates of recent three major political parties in Turkey, the Justice and Development Party (AKP), the Republican People's Party (CHP) and the Nationalist Movement Party (MHP). It also revealed the extent these parties' manifesto documents praise democratic political system across the successive eighteen general elections in the modern Turkish political history. It revealed the changes in both public and party support for four alternative regimes across years in modern Turkish history. This research analyzed the World Values Survey and the Manifesto Project data using quantitative research methods. It has achieved four main findings. First, voters are more stable than their parties across time in terms of pro-democracy. Second, democracy clearly emerges as the strongest alternative among the four alternative regimes for all the three electorates. Third, supporting democracy and rejecting its three alternatives occupy different places in the minds of the three party electorates. Fourth, changes in the three political parties' pro-democracy as identified in their manifesto documents are not always parallel with changes in those of their voters.Article Thermosensitive Pluronic® F127-Based in Situ Gel Formulation Containing Nanoparticles for the Sustained Delivery of Paclitaxel(2023) Unal, Sedat; Aktas, Yesim; Doğan, Osman; Tekeli, Merve CelikBone metastasis is one of the most encountered complications among cancer patients and majority of cancer types has led to bone metastasis. Paclitaxel (PCX) is an anticancer agent commonly used in cancer treatment. However, its clinical use is restricted owing to poor water solubility. PCL NPs were investigated to cope with solubility problem of PCX. The size, polydispersity index and zeta potential of PCL were 383.8±2.4 nm, 0.253±0.122 and +51.3±6.1 mV, respectively. The PCX encapsulation efficiency was 77.2±2.1%. Subsequently, in situ gellling system was prepared by using different Pluronic F-127 concentration in order to determine the optimum ratio. İn situ gel formulation containing 20% Pluronic F-127 was selected as the optimum formulation and subjected to characterization tests. The viscosity of in situ gelling system with CS/PCX-PCL NPs at room temperature (25 °C±0.1) and at body temperature (37 °C±0.1) were found 137.00 ±3.05 cP and 890.30 ±89.61 cP at 100 rpm, respectively. According to the release results, in situ gel provided prolonged release profile compared to PCL NPs alone. Consequently, in situ gel containing CS/PCX-PCL NP elucidated in detail is a promising approach for locally applicable injectable systems.Article Theoretical Investigation of Steric Effects on the S1 Potential Energy Surface of O-Carborane Derivatives(Tubitak Scientific & Technological Research Council Turkey, 2023-01-01) Alkan, FahriTDDFT scan calculations were performed for s-carborane-anthracene derivatives (o-CB-X-Ant where X=-H,-CH3,-C2H5 and tert-butyl or-tBu) in order to understand the interplay between the steric effects, S1 potential energy surface (PES) and photophysical properties. The results show that all systems exhibit three local minima on the S1 PES, which correspond to the emissive LE and TICT state, along with the nonemissive CT state respectively. In the case of the unsubstituted system (o-CB-H-Ant), and-CH3 and-C2H5 substituted cases, S1 PES is predicted to be quite flat for certain conformations indicating that it is possible for these systems to reach the nonemissive CT state without a large energy penalty. In comparison, conformational pathways for the nonemissive CT state are predicted to be energetically unfavorable for o-CB-tBu-Ant as a result of both steric and electronic effects. These results provide a mechanism for the enhanced emission of cr-CB-fluorophore molecules with bulky ligands.Article The Therapeutic Potential of Targeting Hdac6 With Tubastatin a in Tfk-1 and Egi-1 Cholangiocarcinoma Cells(2021) Yenigül, Münevver; Akcok, E. Basak GencerCholangiocarcinoma (CCA) is a highly aggressive and invasive malignancy with a poor diagnosis because of the resistance, relapse and limited therapy. Histone deacetylases (HDAC) are a class of enzyme that have important roles in epigenetic modulations. These enzymes are intensely studied and HDAC inhibitors are considered as potent anticancer agents in both solid tumors and hematological malignancies. HDAC inhibitors can affect and induce different mechanisms such as cell cycle arrest, differentiation, and cell death. In this study, we aim to investigate the cytotoxic effect of Tubastatin A, which is a selective HDAC6 inhibitor, on cholangiocarcinoma cell lines, TFK-1 and EGI-1, by MTT assay. Besides, it was aimed to examine the impact on colony formation potential of the cells. The effect of the inhibitor on cell cycle distribution was also examined by using flow cytometry. Tubastatin A has significantly decreased the colony formation and changed cell cycle progression. Taken together, our results suggest that Tubastatin A could be a potent inhibitor against cholangiocarcinoma. On the basis of these results, further mechanistic studies are required to elucidate the antineoplastic activity of Tubastatin A.Article Citation - WoS: 2Citation - Scopus: 2The Nexus of Leadership, Political Empowerment, and Social Mobilization: The Case of the July 15 Coup Attempt in Turkey(Seta Foundation, 2020-06-30) Donmez, Rasim Ozgur; Timur, Kasim; Lloyd, Fatma Armagan TekeThis study analyzes the mutually empowering relations between Turkish President Recep Tayyip Erdogan and his followers, and how Erdogan's charismatic leadership and image functioned to galvanize his followers on the night of July 15, 2016, when large numbers of them mobilized against the attempted coup. The article has three sections. The first is a theoretical discussion which sheds light on the concept and the underlying mechanisms of political empowerment and its effects on the relationships between leaders and followers. The second section evaluates Erdogan's characteristics and ruling style, which was instrumental in motivating resistance to the abortive coup. Finally, the third section analyzes the various means by which Erdogan was able to inspire the masses to mobilize against the armed junta through interviews and observations.Article Testing a Metacognitive Regulation Approach for Judgment of Satiation: Might Hunger and Fullness Not Be the Polar Opposites of the Same Dimension(2020-12-31) Güzel, Mehmet Akif; Güngör, DuyguDespite the existence of several cognitive influences, metacognitive factors on eating and satiation still remain unclear. Therefore, we investigated a relatively recent metacognitive regulation approach and its measurement method in a lab-experiment.Participants (N=216) were shownphotografsof varying portions of common lunch foods (selected after a separate study, N=94) and asked to makepredicted judgmentsof satiation (JOS) for each via considering their actual hunger levels and whilst imagining other bodily states (e.g., extremely hungry and completely full). Differencescalculated between observed-JOS and their reference scores -thosepresumed to yield accurate matches for the cases-produced either deviances or none at all (discordant-or concordant-JOS). Hungry-group yielded significantly lower concordant-JOS percentage than full-group regardless of portion size, indicating a clearercognitive tendency to lose control over consumption when being hungry than satiated. Critically, full-group could notimagine extreme hunger as hungry-group whereas hungry-group imagined complete fullness just as full-group did, suggesting that whilst hunger was not an obstacle to imagine fullness,fullness hindered the ability to imagine hunger. These findingssuggestthathunger and fullness mightnotbe the polar opposites on the very same dimension, which would, for instance,reveal a need to revisit the treatments of eating disorders accordingly.Article Symbolic Aggregate Approximation-Based Clustering of Monthly Natural Gas Consumption(2024-03-24) Söylemez, İsmet; Ünlü, Ramazan; Nalici, Mehmet ErenNatural gas is an indispensable non-renewable energy source for many countries. It is used in many different areas such as heating and kitchen appliances in homes, and heat treatment and electricity generation in industry. Natural gas is an essential component of the transportation sector, providing a cleaner alternative to traditional fuels in vehicles and fleets. Moreover, natural gas plays a vital role in boosting energy efficiency through the development of combined heat and power systems. These systems produce electricity and useful heat concurrently. As nations move towards more sustainable energy solutions, natural gas has gained prominence as a transitional fuel. This is due to its lower carbon emissions when compared to coal and oil, thus making it an essential component of the global energy framework. In this study, monthly natural gas consumption data of 28 different European countries between 2014 and 2022 are used. Symbolic Aggregate Approximation method is used to analyse the data. Analyses are made with different numbers of segments and numbers of alphabet sizes, and alphabet vectors of each country are created. These letter vectors are used in hierarchical clustering and dendrogram graphs are created. Furthermore, the elbow method is used to determine the appropriate number of clusters. Clusters of countries are created according to the determined number of clusters. In addition, it is interpreted according to the consumption trends of the countries in the determined clusters.Article Citation - WoS: 1Citation - Scopus: 1Study of Helical Antenna Endowing Short Wire Length and Compact Structure for High-Frequency Operations and Its Exclusive Manufacturing Process(Tubitak Scientific & Technological Research Council Turkey, 2023-03-01) Aslan, Melih; Sik, Kaan; Güzelkara, Izzet; Özdür, Ibrahim Tuna; Kilic, Veli TayfunIn this paper a study of a helical antenna resonating at high-frequency (HF) band with a very compact structure is reported. The designed antenna's S11 parameter magnitude change with frequency was calculated for different geometrical parameters. For each case, first, only a single parameter was changed. Then for a fair comparison, multiple parameters were changed simultaneously while the total wire length was set to be constant. Also, shifts in resonance frequencies and variations in -10 dB bandwidths were investigated. Our results show that resonance behaviour changes distinctively with the geometrical parameters and it allows shortening of the antenna wire length. For the designed antenna, the resonances shift to lower frequencies and -10 dB bandwidths around the resonances decrease as the winding wire thickness, number of turns, and turn radius increase. Whereas as the turn spacing increases the resonances shift to higher frequencies and -10 dB bandwidths widen, although the total wire length of the antenna increases. To verify the simulation results, the designed antenna was fabricated with an exclusive manufacturing process and characterized. The measurement results are in good agreement with the simulation results. It demonstrates the feasibility of the proposed manufacturing technique, which is new in the literature and enables accurate and rigid antenna fabrication with simple and low-cost steps.Article Space Prospect in the Flexible Era of Late Capitalism(Konya Technical Univ, Fac Architecture & design, 2020-12-21) Ozmen, Nihan Mus; Asiliskender, BurakThis study is mainly influenced by the idea of Manfredo Tafuri that architecture cannot fulfil its ideological task since it started serving capitalism and there are no more utopias. In his book Architecture and Utopia: Design and Capitalist Development, Tafuri discusses the sociophilosophical tangle in which architects have been struggling since the 18th century. According to Tafuri, the drama of today's architecture is the obligation to return to pure architecture, a matter of form without utopia, supreme uselessness. Another influence on the study is Richard Sennett's book The Corrosion of Character. Sennett mentions the concept of flexible capitalism and explains that work life is not as rigid as it was before. According to Sennett, flexibility has an impact on personal character and asks questions about how to decide the lasting value of we in an impatient society, how to pursue a long-term goal in a short-term economy, how to sustain loyalties to the continually redesigning institutions. Purpose The thoughts of Tafuri and Sennett are discussed through Patrik Schumacher's Parametricism manifesto. In the manifesto, Schumacher reflects architecture's evolving patterns of communication in relation to its social task. The main objective of the study is to propose a future space based on the ideas of Tafuri, Sennett and Schumacher. Design/Methodology/Approach This paper discusses the reviews of books of Tafuri and Sennett and manifesto of Schumacher as a methodology. Findings After the reviews of The Corrosion of Character and Architecture and Utopia, there is a discussion of flexible space through parametric design approach. Finally, there is the prediction of future space based on the findings in the previous sections. Research Limitations/Implications There are no research limitations for this paper. Social/Practical Implications According to this paper, parametric design method can be used in practice to achieve the spaces that are needed by the complex society of global era. Originality/Value This paper synthesizes the ideas of two great thinkers, who have influential discourses on architecture and business world, and approaches them from the perspective of parametric design as one of today's design tools, to make predictions about the future space.