TR-Dizin İndeksli Yayınlar Koleksiyonu
Permanent URI for this collectionhttps://hdl.handle.net/20.500.12573/396
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Article Modeling and Simulation of Dynamic Energy Management Systems for Smart Buildings(TÜBİTAK, 2025-11-25) Ozel, O.; Rıfat Boynueğrİ, A.; Yigit, H.; Tekgun, B.; Boynuegri, Ali RifatThis study presents a dynamic energy management system tailored for smart residential buildings, integrating thermal and electrical models to achieve both natural gas and electricity bill cost reduction. By harnessing wind and solar energy sources, the system aims to meet the diverse energy needs of modern homes. Through load shifting and thermal storage strategies, known as power-to-heat (P2H) approaches, the system ensures efficient renewable energy utilization while maintaining resident comfort. Validation of the proposed system was conducted using real-world data from the Yıldız Technical University Smart Home Laboratory, demonstrating its practical applicability and effectiveness. Results indicate significant reductions in both natural gas and electricity consumption, leading to substantial cost savings. Specifically, the proposed system reduced natural gas consumption by 3.79% and electricity consumption by 35.62%, highlighting its potential to enhance energy efficiency and sustainability in residential settings. © This work is licensed under a Creative Commons Attribution 4.0 International License.Article Citation - WoS: 1Comprehensive Prediction of FBN1 Targeting Mirnas: A Systems Biology Approach for Marfan Syndrome(Galenos Publishing House, 2025-09-22) Orhan, M.E.; Demirci, Y.M.; Saçar Demirci, M.D.S.; Demirci, Muserref Duygu SacarObjective: Marfan syndrome (MFS) is a genetic connective tissue disorder primarily caused by mutations in the FBN1 gene. Emerging evidence highlights the regulatory role of microRNAs (miRNAs) in modulating gene expression in MFS, but a systematic investigation into miRNAs targeting FBN1 is lacking. This study aimed to comprehensively identify miRNAs interacting with the FBN1 transcript to reveal potential molecular regulators and therapeutic targets. Methods: Human miRNA sequences were retrieved from miRBase (Release 22.1), and the canonical FBN1 transcript (RefSeq: NM_000138.5) was used for target prediction. Computational interaction analysis was conducted using the psRNATarget server with stringent parameters to detect potential miRNA binding sites. Expression profiles and disease associations of the top candidate miRNAs were further investigated through database integration and literature review. Results: Out of 2656 human mature miRNAs analyzed, 251 were predicted to bind FBN1, with the hsa-miR-181 family exhibiting the highest number of predicted interactions. Evidence from the literature highlighted dysregulation of hsa-miR-181 expression in MFS patients, suggesting a functional role in disease pathophysiology. Conclusion: This study identifies key members of the hsa-miR-181 family as post-transcriptional regulators of FBN1, offering new insights into miRNA-driven mechanisms in MFS. These findings support the potential of RNA-based diagnostics and therapeutic strategies targeting miRNA-FBN1 interactions. ©Copyright 2025 The Author.Article Forecasting the Consumer Price Index in Türkiye Using Machine Learning Models: A Comparative Analysis(Gazi Univ, 2025-09-01) Söylemez, İsmet; Ünlü, Ramazan; Nalici, Mehmet ErenThis study utilizes machine learning models to forecast Türkiye's Consumer Price Index (CPI), thereby addressing a critical gap in inflation prediction methodologies. The central research problem involves the forecasting of CPI in a volatile economic environment, which is essential for informed policymaking. The primary objective of this study is to evaluate the performance of three machine learning models, such as Decision Tree (DT), Random Forest (RF), and Support Vector Machine (SVM), in forecasting CPI over periods ranging from one to six months, utilizing data from 2012 to 2024. The study's unique contribution lies in the application of the \"SelectKBest\" method, which identifies the most relevant indices, thereby enhancing the efficiency of the models. An ensemble method, Averaging Voting, is also employed to combine the strengths of these models, producing more accurate and robust predictions. The findings indicate that while the RF model consistently generates the most accurate forecasts across all shifts, the SVM model demonstrates a particular strength in the domain of short-term predictions. The ensemble model demonstrates a substantial performance improvement, with a R2 value of 0.962 for one-month ahead of estimates and 0.956 for five-month forecasts. This combined approach has been shown to outperform individual models, offering a more reliable framework for CPI forecasting. The findings offer valuable insights for economic policymakers, enabling more precise and stable inflation predictions in Türkiye.Other Barriers in Sustainable Lean Supply Chain Management: Implementation in SMEs(Ege Univ, Fac. Economics & Admin. Sciences, 2025-02-04) Kazancoglu, Yigit; Takcı, Ebru; Ada, ErhanAs the world undergoes significant transformations in various domains, including technology, energy supply and communication, the idea of sustainability has become a significant issue. This study investigates the barriers to Sustainable Lean Supply Chain (SLSC) management within Small and Medium-Sized Enterprises (SMEs) and explores the structural interrelationships among these barriers. A comprehensive literature review was carried out to recognize critical elements relevant to the research topic, resulting in the identification of fifteen specific elements that account for 85% of the barriers in SLSC management. The DEMATEL method was used to evaluate the significance and influence levels of these factors. Furthermore, structured in-depth interviews were conducted with ten experts representing sectors that constitute 85% of the SMEs operating in Kayseri Organized Industrial Zone (OIZ), Turkey, including metal products, furniture, plastic packaging, construction materials, textiles and food. The findings reveal that strategies represent the most significant barrier to SLSC management in SMEs. The barriers were analyzed in two dimensions: influencing and influenced factors. The primary influencing factor identified was laws, standards, regulations, and legislation while the most significant influenced factor was found supply and suppliers. The study concludes with findings and actionable recommendations for practitioners and decision-makers.Article An Opportunity for Nuri Demirağ the National Development Party the Transition to Multiparty Life in Turkey(Osman Kose, 2023) Karatas, Murat; Solak, YeterThe political life in Turkey during the period of 1923-1945 showed a single-party characteristic. Turkey, which did not enter the Second World War in 1939-1945, faced some negativities brought by the war both during and after the war. These negativities have had a compelling effect on the government to switch to a multi-party system with the effect of external and internal factors. Nuri Demira & gbreve; founded the National Development Party while he was preparing to take a step towards a multiparty system in Turkey, forced by both domestic and foreign conditions. Although the party could not show an active presence in our political life, its establishment made an important contribution to the establishment of democracy culture and the Despite all the efforts of Nuri Demira & gbreve; as the founder and chairman of the party, the inconsistency in the party and the evaluation of party activities from the wrong points led to the party's indifference in political life. In 1957, the existence of the National Development Party in our political life came to an end quietly due to the fact that the party committee could not convene after the death of the party chairman, Nuri Demira & gbreve;.In this sense, our study aims to contribute to the literature by aiming to discuss the political adventure of the National Development Party, which stands at an important point in terms of the democratization process in our political life, and to reveal the role of its founder, Nuri Demirag, in this process.
