Scopus İndeksli Yayınlar Koleksiyonu

Permanent URI for this collectionhttps://hdl.handle.net/20.500.12573/395

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In-silico Identification of Papillary Thyroid Carcinoma Molecular Mechanisms
(IEEE, 345 E 47TH ST, NEW YORK, NY 10017 USA, 2019) Ersoz, Nur Sebnem; Guzel, Yasin; Bakir-Gungor, Burcu
Representing approximately 70% to 80% of thyroid cancers, papillary thyroid cancer (PTC) is the most common type of thyroid cancers. PTC is seen in all age groups, but it is seen more frequently in women than in men. Detection of biomarker proteins of papillary thyroid cancinoma plays an important role in the diagnosis of the disease. In this study, we aim to find target genes and pathways that are associated with papillar thyroid carcinoma, by integrating different bioinformatics methods. For this purpose, usingin-silico methodologies, candidate genes and pathways that could explain disease development mechanisms are identified. Throughout this study, firstly we identified differentially expressed genes as the amount of their protein product differ between patient and healthy groups. Secondly, by using active subnetworks search algorithms, topologic analyses and functional enrichment tests, candidate proteins,which could be thought as PTC biomarkers, and affected pathways are identified.
Structure Health Monitoring Using Wireless Sensor Networks on Structural Elements (vol 82, pg 68, 2019)
(ELSEVIER, RADARWEG 29, 1043 NX AMSTERDAM, NETHERLANDS, 2020) Ayyildiz, Cem; Erdem, H. Emre; Dirikgil, Tamer; Dugenci, Oguz; Kocak, Taskin; Altun, Fatih; Gungor, V. Cagri
This paper presents a system that monitors the health of structural elements in Reinforced Concrete (RC), concrete elements and/or masonry buildings and warn the authorities in case of physical damage formation. Such rapid and reliable detection of impairments enables the development of better risk management strategies to prevent casualties in case of earthquake and floods. Piezoelectric (PZT) sensors with lead zirconate titanate material are the preferred sensor type for fracture detection. The developed sensor mote hardware triggers the PZT sensors and collects the responses they gather from the structural elements. It also sends the collected data to a data center for further processing and analysis in an energy-efficient manner utilizing low-power wireless communication technologies. The access and the analysis of the collected data can be remotely performed via a web interface. Performance results show that the fractures serious enough to cause structural problems can be successfully detected with the developed system.
Positive Solutions of Multipoint Φ-Laplacian BVPS With First-Order Derivative Dependence
(World Scientific, 2023) Bachouche, Kamal; Tair, Hocine; Doǧan, Abdülkadir Muhittin
This paper concerns existence of positive solutions for a second-order boundary value problem of Sturm-Liouville type associated with a φ-Laplacian operator and posed on a bounded interval. Existence results are obtained by an adapted version of the Krasnosel'skii's fixed point theorem of cone expansion and compression. Some examples illustrate our results. © 2023 Elsevier B.V., All rights reserved.
Ensemble Churn Prediction for Internet Service Provider with Machine Learning Techniques
(IEEE, 345 E 47TH ST, NEW YORK, NY 10017 USA, 2020) Goy, Gokhan; Kolukisa, Burak; Bahcevan, Cenk; Gungor, Vehbi Cagri
With the developing technology in every fields, a competitive marketing environment has been arised In this competitive environment analyzing customer behavior has become vital In particular, the ability to easily change any service provider has become vet) , critical for the company to continue its existence At the same time, the amount of financial resources spent on retaining instituters much less than to obtain new clients. In this context, the traditional methods of examining vast amount of data obtained today for establishing decision support systems have lost their validities In this study. we used a dataset which is provided by TurkNet serving as an internet service provider in Turkey. Various preprocessing steps has performed on this dataset and then classification algorithms ran. Afterwards results have obtained and compared. The results of these experiments analyzed in terms of the area under the curve value In this context the aunt successful classifier algorithm has been determined as the Random Trees algorithm with a value of 0.936.
Citation - Scopus: 2
Street Vendor Detection: Helping Municipalities Make Decisions With Actionable Insights
(IEEE, 2021) Agba, Hatice Nur; Tahir, Abdullah
Street vendors are quite common in countries across the world. By the prevalence of mobile surveillance systems, increasing demand for automatic detection of street vendors for further decisions and planning by the city administrators emerged. In this paper, an object detector is developed using a MobileNet SSD object detection algorithm to detect vendors on the street. For this study images were used, however, in the future this technique could be used for real time video footage from street cameras. Since this is the first study tackling this issue, a data set was created from scratch. The accuracy achieved by the algorithm is promising considering the size of the data set and the minimal computational power available. The goal of this research is to pave the way for more work to be done in this area and help municipalities improve their decision making process regarding street vendor activities in countries like Mexico, Pakistan, China, Turkey, etc.
Evaluation of Hybrid Classification Approaches: Case Studies on Credit Datasets
(Springer Verlag service@springer.de, 2018) Cetiner, Erkan; Güngör, Vehbi Çağrı; Kocak, Taskin
Hybrid classification approaches on credit domain are widely used to obtain valuable information about customer behaviours. Single classification algorithms such as neural networks, support vector machines and regression analysis have been used since years on related area. In this paper, we propose hybrid classification approaches, which try to combine several classifiers and ensemble learners to boost accuracy on classification results. We worked with two credit datasets, German dataset which is a public dataset and a Turkish Corporate Bank dataset. The goal of using such diverse datasets is to search for generalization ability of proposed model. Results show that feature selection plays a vital role on classification accuracy, hybrid approaches which shaped with ensemble learners outperform single classification techniques and hybrid approaches which consists SVM has better accuracy performance than other hybrid approaches. © 2018 Elsevier B.V., All rights reserved.
Citation - Scopus: 1
Man-Hour Prediction for Complex Industrial Products
(Institute of Electrical and Electronics Engineers Inc., 2023) Unal, Ahmet Emin; Boyar, Halit; Kuleli Pak, Burcu Kuleli; Cem Yildiz, Mehmet; Erten, Ali Erman; Güngör, Vehbi Çağrı
Accurately predicting the cost is crucial for the success of complex industrial projects. There can be several sources contributing to the cost. Traditional methods for cost estimation may not provide the required accuracy and speed to ensure the success of the project. Recently, machine learning techniques have shown promising results in improving cost estimation in various industrial products. This study investigates the performance of gradient-boosting machine learning models and feature engineering techniques on a private dataset of metal sheet project man-hour costs. A comparison of distinct models is conducted, key aspects influencing cost are identified, and the implications of incorporating domain-specific knowledge, including its advantages and disadvantages, are assessed based on performance outcomes. Experimental results demonstrate that LightGBM and XGBoost outperform other models, and feature selection and synthetic data generation techniques improve the performance. Overall, this study highlights the potential of machine learning in metal sheet sampling projects and emphasizes the importance of feature engineering and domain expertise for better model performance. © 2024 Elsevier B.V., All rights reserved.
Human identification using palm print images based on deep learning methods and gray wolf optimization algorithm
(SPRINGER, 2024) Alshakree, Firas; Akbas, Ayhan; Rahebi, Javad
Palm print identification is a biometric technique that relies on the distinctive characteristics of a person’s palm print to distinguish and authenticate their identity. The unique pattern of ridges, lines, and other features present on the palm allows for the identification of an individual. The ridges and lines on the palm are formed during embryonic development and remain relatively unchanged throughout a person’s lifetime, making palm prints an ideal candidate for biometric identification. Using deep learning networks, such as GoogLeNet, SqueezeNet, and AlexNet combined with gray wolf optimization, we achieved to extract and analyze the unique features of a person’s palm print to create a digital representation that can be used for identification purposes with a high degree of accuracy. To this end, two well-known datasets, the Hong Kong Polytechnic University dataset and the Tongji Contactless dataset, were used for testing and evaluation. The recognition rate of the proposed method was compared with other existing methods such as principal component analysis, including local binary pattern and Laplacian of Gaussian-Gabor transform. The results demonstrate that the proposed method outperforms other methods with a recognition rate of 96.72%. These findings show that the combination of deep learning and gray wolf optimization can effectively improve the accuracy of human identification using palm print images.
Identification of Shared Pathways Among Immune Related Diseases Utilizing Active Subnetworks
(IEEE, 345 E 47TH ST, NEW YORK, NY 10017 USA, 2020) Eryilmaz, Mahmut Kaan; Kuzudisli, Cihan; Gungor, Burcu Bakir
Different, but related diseases often contain shared symptoms indicating the presence of possible overlaps in underlying pathogenic mechanisms. The identification of the shared pathways and related factors across these diseases helps to better understand the causes of these diseases, to prevent and treat these diseases. In this study, using immune-related diseases, we proposed a new method on how to compare the development mechanisms of related diseases based on biological pathways. Following the developments in genomic technologies, the genotyping gets cheaper and easier, and hence genome-wide association studies (GWAS) emerged. By this means, via studying big-sized case-control groups for a specific disease, potential genetic variations, single nucleotide polymorphisms (SNPs) could he identified. With the help of these studies, in which around a million of SNPs are scanned, the variations and genes that could have a role in specific disease development could be detected. In this study, via using available GWAS datasets and human protein-protein interaction network, and via detecting active subnetworks and affected pathways, seven immune related diseases are analyzed. Via investigating the similarities among the identified pathways for related diseases, we aim to define the underlying pathogenic mechanisms, and hence to contribute to the elucidation of disease development mechanisms and to the drug repositioning studies.
Citation - WoS: 15
Citation - Scopus: 16
Stacking Ensemble Learning-Based Wireless Sensor Network Deployment Parameter Estimation
(Springer Heidelberg, 2023) Akbas, Ayhan; Buyrukoglu, Selim
In wireless sensor network projects, it is generally desired to cover the area to be monitored at a given cost and to achieve the maximum useful network lifetime. In the deployment of the wireless sensors, it is necessary to know in advance how many sensor nodes will be required, how much the distance between the nodes should be, etc., or what the transmit power level should be, etc. depending on the channel parameters of the area. This necessitates accurate calculation of variables such as maximum network lifetime, communication channel parameters, number of nodes to be used, and distance between nodes. As numbers reach to the order of hundreds, calculation tends to a NP hard problem to solve. At this point, we employed both single-based and stacked ensemble-based machine learning models to speed up the parameter estimations with highly accurate outcomes. Adaboost was superior over other models (Elastic Net, SVR) in single-based models. Stacked ensemble models achieved best results for the WSN parameter prediction compared to single-based models.
Citation - WoS: 44
Citation - Scopus: 52
CBI4.0: A Cross-Layer Approach for Big Data Gathering for Active Monitoring and Maintenance in the Manufacturing Industry 4.0
(Elsevier, 2021) Faheem, Muhammad; Butt, Rizwan Aslam; Ali, Rashid; Raza, Basit; Ngadi, Md Asri; Gungor, Vehbi Cagri
Industry 4.0 (I4.0) defines a new paradigm to produce high-quality products at the low cost by reacting quickly and effectively to changing demands in the highly volatile global markets. In Industry 4.0, the adoption of Internet of Things (IoT)-enabled Wireless Sensors (WSs) in the manufacturing processes, such as equipment, machining, assembly, material handling, inspection, etc., generates a huge volume of data known as Industrial Big Data (IBD). However, the reliable and efficient gathering and transmission of this big data from the source sensors to the floor inspection system for the real-time monitoring of unexpected changes in the production and quality control processes is the biggest challenge for Industrial Wireless Sensor Networks (IWSNs). This is because of the harsh nature of the indoor industrial environment that causes high noise, signal fading, multipath effects, heat and electromagnetic interference, which reduces the transmission quality and trigger errors in the IWSNs. Therefore, this paper proposes a novel cross-layer data gathering approach called CBI4.0 for active monitoring and control of manufacturing processes in the Industry 4.0. The key aim of the proposed CBI4.0 scheme is to exploit the multi-channel and multi-radio architecture of the sensor network to guarantee quality of service (QoS) requirements, such as higher data rates, throughput, and low packet loss, corrupted packets, and latency by dynamically switching between different frequency bands in the Multichannel Wireless Sensor Networks (MWSNs). By performing several simulation experiments through EstiNet 9.0 simulator, the performance of the proposed CBI4.0 scheme is compared against existing studies in the automobile Industry 4.0. The experimental outcomes show that the proposed scheme outperforms existing schemes and is suitable for effective control and monitoring of various events in the automobile Industry 4.0.
A New Method to Identify Affected Pathway Subnetworks and Clusters in Colon Cancer
(IEEE, 345 E 47TH ST, NEW YORK, NY 10017 USA, 2019) Goy, Gokhan; Yazici, Miray Unlu; Bakir-Gungor, Buren
Nowadays new technological developments that play an important role in the production of big data have brought about the interpretation, sharing and storage of data related to complex diseases. Combining multi-omic data in different molecular levels is potentially important for understanding the biological origin of complex diseases. One of these complex diseases is cancer of different types, which has one of the highest causes of death worldwide. The integration of multiple omic data in the framework of a comprehensive analysis and identification of relevant pathways contribute to the development of therapeutic approaches related to disease. In this study, RNA and methylation data (genes and p values) of colon adenocarcinoma were obtained from TCGA data portal and combined with Fisher's method. While protein subnetworks affected by the disease were identified by using subnetwork algorithm, pathways related to the disease and genes associated with these pathways were determined by functional enrichment analysis. Using gene-pathway relationship matrix, kappa scores of pathways were determined by similarity calculation. In this way, the pathways were clustered according to the hierarchically optimal number, as a result, the most important pathway clusters and related genes that are effective in disease formation identified.

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