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Permanent URI for this collectionhttps://hdl.handle.net/20.500.12573/394
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Article GenShare: A Blockchain-Based Genomic Data Sharing Platform(Association for Computing Machinery, 2026-01-27) Dedeturk, B.A.; Soran, A.; Bakir-Güngör, B.Every day, hundreds of gigabytes of data are produced due to the exponential growth of next-generation sequencing and omics technologies. By combining omics data with other data types, such as electronic health record data, panomics research is actively attempting to uncover novel and potentially useful biomarkers. For the effective analysis of high-throughput-derived omics data, it is imperative to establish robust and reliable platforms that prioritize ethical considerations while effectively managing privacy, ownership concerns, and the responsible sharing of data. The GenShare model was proposed to provide an efficient platform that fits these needs. GenShare is a hybrid platform that utilizes blockchain technology. Paillier’s homomorphic encryption scheme in tandem with Intel Software Guard Extension (SGX) serves to enable the sharing of genomic data, execution of count queries, and statistical analysis of genomic data while preserving privacy and avoiding compromise of sensitive information. The objective of this paradigm is to confront security and privacy concerns through the integration of homomorphic encryption and SGX, addressing additional challenges associated with Hyperledger Fabric and Ethereum. In pursuit of this objective, the implementation of the system involved establishing the Hyperledger Fabric network, with various workloads employed to assess the network’s efficiency. Consequently, it was hypothesized that the new GenShare model would enhance the data collection and dissemination cycle and serve as a proficient platform catering to the needs of its users. © 2026 Copyright held by the owner/author(s).Article Citation - WoS: 6Citation - Scopus: 4Towards Global Sustainable Development: The Role of Financial Innovation and Technological Advancements(Sage Publications Ltd, 2024-08-10) Dogan, Eyup; Chishti, Muhammad Zubair; Zaman, Umer; Binsaeed, Rima H.The importance of metaverse and blockchain technologies in today's global landscape cannot be overstated. These innovative technologies offer transformative potential for various sectors, including economics, by enhancing connectivity, security and transparency. The present study leverages these technologies to investigate their dynamic impacts, in conjunction with geopolitical risk, on global economic cycles to navigate the challenges of an interconnected world. To ensure the reliability of our findings, this study employs two proxies to gauge economic cycles: global green economic growth and global environmental sustainability. By utilizing daily data, this study reveals several noteworthy findings. First, the quantile-var-based network analysis demonstrates a robust directional connection among the variables in our model. Second, the wavelet quantile correlation technique uncovers the significant role of metaverse technology in influencing economic cycles by promoting global green economic growth and global environmental sustainability across all time horizons (short, medium and long term). Third, economic cycles exhibit a negative association with financial innovation and a positive connection with geopolitical risk across all timeframes. Fourth, the continuous wavelet transform causality test identifies a substantial causal relationship running from metaverse technology, financial innovation and geopolitical risk to economic cycles. Based on our empirical results, this study recommends that the global economy should continue investing in metaverse and blockchain technologies to address economic cycles in the future.Article Citation - WoS: 16Citation - Scopus: 23Review on Energy Application Using Blockchain Technology With an Introductions in the Pricing Infrastructure(IEEE-Inst Electrical Electronics Engineers Inc, 2022) Al-Abri, Tariq; Onen, Ahmet; Al-Abri, Rashid; Hossen, Abdulnasir; Al-Hinai, Amer; Jung, Jaesung; Ustun, Taha SelimWith the rapid transformation of the energy sector towards modern power systems represented by smart grids (SGs), microgrids (MG), and distributed generation, blockchain (BC) technology has shown the capability for solving security, privacy, and reliability challenges that hinder progress. Currently, the energy structure is forming a decentralized system that prioritizes customer satisfaction. BC technology undertakes power network stockholders in a secure energy market, transparent transactions, and fair competition and offers promising energy solutions. This paper is a comprehensive review of energy applications using BC integration. Firstly, we introduce the drivers of BC leverage that make it a potentially important component of the power network. Following that, we provide background information on BC and its application in areas other than the energy sector. Subsequently, we discuss studies and sort potential energy applications from various recent papers and surveys that have already adopted BC technology in the energy sector. Then, we summarize the pricing infrastructure for applying BC in the energy sector and identify the requirements to build it. Finally, energy security and privacy challenges based on BC are highlighted, along with potential drawbacks and concerns related to the pricing infrastructure.Article Citation - WoS: 115Citation - Scopus: 173Peer-to-Peer Energy Trading in Virtual Power Plant Based on Blockchain Smart Contracts(IEEE-Inst Electrical Electronics Engineers Inc, 2020) Seven, Serkan; Yao, Gang; Soran, Ahmet; Onen, Ahmet; Muyeen, S. M.A novel Peer-to-peer (P2P) energy trading scheme for a Virtual Power Plant (VPP) is proposed by using Smart Contracts on Ethereum Blockchain Platform. The P2P energy trading is the recent trend the power society is keen to adopt carrying out several trial projects as it eases to generate and share the renewable energy sources in a distributed manner inside local community. Blockchain and smart contracts are the up-and-coming phenomena in the scene of the information technology used to be considered as the cutting-edge research topics in power systems. Earlier works on P2P energy trading including and excluding blockchain technology were focused mainly on the optimization algorithm, Information and Communication Technology, and Internet of Things. Therefore, the financial aspects of P2P trading in a VPP framework is focused and in that regard a P2P energy trading mechanism and bidding platform are developed. The proposed scheme is based on public blockchain network and auction is operated by smart contract addressing both cost and security concerns. The smart contract implementation and execution in a VPP framework including bidding, withdrawal, and control modules developments are the salient feature of this work. The proposed architecture is validated using realistic data with the Ethereum Virtual Machine (EVM) environment of Ropsten Test Network.Article Citation - WoS: 27Citation - Scopus: 31Energy Trading on a Peer-to-Peer Basis Between Virtual Power Plants Using Decentralized Finance Instruments(MDPI, 2022-10-16) Seven, Serkan; Yoldas, Yeliz; Soran, Ahmet; Alkan, Gulay Yalcin; Jung, Jaesung; Ustun, Taha Selim; Onen, Ahmet; Yalcin Alkan, GulayOver time, distribution systems have begun to include increased distributed energy resources (DERs) due to the advancement of auxiliary power electronics, information and communication technologies (ICT), and cost reductions. Electric vehicles (EVs) will undoubtedly join the energy community alongside DERs, and energy transfers from vehicles to grids and vice versa will become more extensive in the future. Virtual power plants (VPPs) will also play a key role in integrating these systems and participating in wholesale markets. Energy trading on a peer-to-peer (P2P) basis is a promising business model for transactive energy that aids in balancing local supply and demand. Moreover, a market scheme between VPPs can help DER owners make more profit while reducing renewable energy waste. For this purpose, an inter-VPP P2P trading scheme is proposed. The scheme utilizes cutting-edge technologies of the Avalanche blockchain platform, developed from scratch with decentralized finance (DeFi), decentralized applications (DApps), and Web3 workflows in mind. Avalanche is more scalable and has faster transaction finality than its layer-1 predecessors. It provides interoperability abilities among other common blockchain networks, facilitating inter-VPP P2P trading between different blockchain-based VPPs. The merits of DeFi contribute significantly to the workflow in this type of energy trading scenario, as the price mechanism can be determined using open market-like instruments. A detailed case study was used to examine the effectiveness of the proposed scheme and flow, and important conclusions were drawn.Conference Object Citation - WoS: 4Blockchain-Based Fog Computing Applications in Healthcare(IEEE, 2020-10-05) Adanur, Beyhan; Bakir-Gungor, Burcu; Soran, AhmetRecently, the use of blockchain technology in the field of healthcare has increased. Although blockchain technology brought several innovations to healthcare, still there are problems waiting to be resolved. In order to provide alternative solutions to these problems, the use of fog computing together with blockchain technology has been proposed. In this study, the applications of blockchain based fog computing technology in healthcare are investigated. The aim of this study is to provide the readers an idea about the interactive use of blockchain and fog computing in the field of healthcare. For this purpose, firstly, fog computing and blockchain technologies are introduced. Afterwards, the integration of these areas, the advantages and disadvantages of using these technologies in the field of healthcare is discussed and a new system architecture is proposed.Article Citation - WoS: 18Citation - Scopus: 29Blockchain for Genomics and Healthcare: A Literature Review, Current Status, Classification and Open Issues(PeerJ Inc, 2021-09-30) Dedeturk, Beyhan Adanur; Soran, Ahmet; Bakir-Gungor, BurcuThe tremendous boost in the next generation sequencing technologies and in the "omics"technologies resulted in the generation of hundreds of gigabytes of data per day. Nowadays, via integrating -omics data with other data types, such as imaging and electronic health record (EHR) data, panomics studies attempt to identify novel and potentially actionable biomarkers for personalized medicine applications. In this respect, for the accurate analysis of -omics data and EHR, there is a need to establish secure and robust pipelines that take the ethical aspects into consideration, regulate privacy and ownership issues, and data sharing. These days, blockchain technology has picked up significant attention in diverse fields, including genomics, since it offers a new solution for these problems from a different perspective. Blockchain is an immutable transaction ledger, which offers secure and distributed system without a central authority. Within the system, each transaction can be expressed with cryptographically signed blocks, and the verification of transactions is performed by the users of the network. In this review, firstly, we aim to highlight the challenges of EHR and genomic data sharing. Secondly, we attempt to answer "Why"or "Why not"the blockchain technology is suitable for genomics and healthcare applications in detail. Thirdly, we elucidate the general blockchain structure based on the Ethereum, which is a more suitable technology for the genomic data sharing platforms. Fourthly, we review current blockchain-based EHR and genomic data sharing platforms, evaluate the advantages and disadvantages of these applications, and classify these applications using different metrics. Finally, we conclude by discussing the open issues and introducing our suggestion on the topic. In summary, to facilitate the diagnosis, monitoring and therapy of diseases with the effective analysis of -omics data with other available data types, through this review, we put forward the possible implications of the blockchain technology to life sciences and healthcare.Article Citation - WoS: 18Citation - Scopus: 27BlockFaas: Blockchain-Enabled Serverless Computing Framework for AI-Driven IoT Healthcare Applications(Springer, 2023-11-03) Golec, Muhammed; Gill, Sukhpal Singh; Golec, Mustafa; Xu, Minxian; Ghosh, Soumya K.; Kanhere, Salil S.; Uhlig, SteveWith the development of new sensor technologies, Internet of Things (IoT)-based healthcare applications have gained momentum in recent years. However, IoT devices have limited resources, making them incapable of executing large computational operations. To solve this problem, the serverless paradigm, with its advantages such as dynamic scalability and infrastructure management, can be used to support the requirements of IoT-based applications. However, due to the heterogeneous structure of IoT, user trust must also be taken into account when providing this integration. This problem can be overcome by using a Blockchain that guarantees data immutability and ensures that any data generated by the IoT device is not modified. This paper proposes a BlockFaaS framework that supports dynamic scalability and guarantees security and privacy by integrating a serverless platform and Blockchain architecture into latency-sensitive Artificial Intelligence (AI)-based healthcare applications. To do this, we deployed the AIBLOCK framework, which guarantees data immutability in smart healthcare applications, into HealthFaaS, a serverless-based framework for heart disease risk detection. To expand this framework, we used high-performance AI models and a more efficient Blockchain module. We use the Transport Layer Security (TLS) protocol in all communication channels to ensure privacy within the framework. To validate the proposed framework, we compare its performance with the HealthFaaS and AIBLOCK frameworks. The results show that BlockFaaS outperforms HealthFaaS with an AUC of 4.79% and consumes 162.82 millijoules less energy on the Blockchain module than AIBLOCK. Additionally, the cold start latency value occurring in Google Cloud Platform, the serverless platform into which BlockFaaS is integrated, and the factors affecting this value are examined.Article Citation - Scopus: 4Aguhyper: A Hyperledger-Based Electronic Health Record Management Framework(PeerJ Inc, 2024-05-22) Dedeturk, Beyhan Adanur; Bakir-Gungor, BurcuThe increasing importance of healthcare records, particularly given the emergence of new diseases, emphasizes the need for secure electronic storage and dissemination. With these records dispersed across diverse healthcare entities, their physical maintenance proves to be excessively time-consuming. The prevalent management of electronic healthcare records (EHRs) presents inherent security vulnerabilities, including susceptibility to attacks and potential breaches orchestrated by malicious actors. To tackle these challenges, this article introduces AguHyper, a secure storage and sharing solution for EHRs built on a permissioned blockchain framework. AguHyper utilizes Hyperledger Fabric and the InterPlanetary Distributed File System (IPFS). Hyperledger Fabric establishes the blockchain network, while IPFS manages the off -chain storage of encrypted data, with hash values securely stored within the blockchain. Focusing on security, privacy, scalability, and data integrity, AguHyper ' s decentralized architecture eliminates single points of failure and ensures transparency for all network participants. The study develops a prototype to address gaps identi fi ed in prior research, providing insights into blockchain technology applications in healthcare. Detailed analyses of system architecture, AguHyper ' s implementation con fi gurations, and performance assessments with diverse datasets are provided. The experimental setup incorporates CouchDB and the Raft consensus mechanism, enabling a thorough comparison of system performance against existing studies in terms of throughput and latency. This contributes signi fi cantly to a comprehensive evaluation of the proposed solution and offers a unique perspective on existing literature in the fi eld.Conference Object Citation - WoS: 4Citation - Scopus: 10Sağlıkta Blokzincir Tabanlı Sistem Bilişimi Uygulamaları(Institute of Electrical and Electronics Engineers Inc., 2020-10-05) Dedeturk, Beyhan Adanur; Bakir-Güngör, Burcu; Soran, Ahmet; Adanur, BeyhanRecently, the use of blockchain technology in the field of healthcare has increased. Although blockchain technology brought several innovations to healthcare, still there are problems waiting to be resolved. In order to provide alternative solutions to these problems, the use of fog computing together with blockchain technology has been proposed. In this study, the applications of blockchain based fog computing technology in healthcare are investigated. The aim of this study is to provide the readers an idea about the interactive use of blockchain and fog computing in the field of healthcare. For this purpose, firstly, fog computing and blockchain technologies are introduced. Afterwards, the integration of these areas, the advantages and disadvantages of using these technologies in the field of healthcare is discussed and a new system architecture is proposed. © 2021 Elsevier B.V., All rights reserved.