WoS İndeksli Yayınlar Koleksiyonu
Permanent URI for this collectionhttps://hdl.handle.net/20.500.12573/394
Browse
2 results
Search Results
Article Citation - WoS: 13Citation - Scopus: 20IGPRED: Combination of Convolutional Neural and Graph Convolutional Networks for Protein Secondary Structure Prediction(Wiley, 2021-05-25) Gormez, Yasin; Sabzekar, Mostafa; Aydin, ZaferThere is a close relationship between the tertiary structure and the function of a protein. One of the important steps to determine the tertiary structure is protein secondary structure prediction (PSSP). For this reason, predicting secondary structure with higher accuracy will give valuable information about the tertiary structure. Recently, deep learning techniques have obtained promising improvements in several machine learning applications including PSSP. In this article, a novel deep learning model, based on convolutional neural network and graph convolutional network is proposed. PSIBLAST PSSM, HHMAKE PSSM, physico-chemical properties of amino acids are combined with structural profiles to generate a rich feature set. Furthermore, the hyper-parameters of the proposed network are optimized using Bayesian optimization. The proposed model IGPRED obtained 89.19%, 86.34%, 87.87%, 85.76%, and 86.54% Q3 accuracies for CullPDB, EVAset, CASP10, CASP11, and CASP12 datasets, respectively.Article Citation - Scopus: 1Breast Cancer Detection Using a New Parallel Hybrid Logistic Regression Model Trained by Particle Swarm Optimization and Clonal Selection Algorithms(Wiley, 2025-04-29) Etcil, Mustafa; Dedeturk, Bilge Kagan; Kolukisa, Burak; Bakir-Gungor, Burcu; Gungor, Vehbi CagriBreast cancer is one of the most widespread kinds of cancer, especially in women, and it has a high mortality rate. With the help of technology, it is possible to develop a computer-aided method for the diagnosis of breast cancer, which is crucial for effective treatment. Recent breast cancer diagnosis studies utilizing numerous machine learning models were efficient and innovative. However, it has been observed that they may have problems such as long training times and low accuracy rates. To this end, in this study, we present a new classifier that utilizes a hybrid of the clonal selection algorithm (CSA) and the particle swarm optimization (PSO) algorithm for the training of the logistic regression (LR) model, which is named CSA-PSO-LR. The proposed method is evaluated using two publicly accessible breast cancer datasets, that is, the Wisconsin Diagnostic Breast Cancer (WDBC) database and the Wisconsin Breast Cancer Database (WBCD), with 10-fold cross-validation and Bayesian hyperparameter optimization techniques. Additionally, a CPU parallelization method is applied, which substantially shortens the training time of the model. The efficacy of the CSA-PSO-LR classifier is compared with state-of-the-art machine learning algorithms and related studies in the literature. Performance analysis indicates that the proposed method achieves 98.75% accuracy and 98.27% F1-score on the WDBC dataset, and 97.94% accuracy and 97.35% F1-score on the WBCD dataset. These results demonstrate the potential of the proposed method as an effective approach for improving breast cancer diagnosis.