WoS İndeksli Yayınlar Koleksiyonu
Permanent URI for this collectionhttps://hdl.handle.net/20.500.12573/394
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Article Citation - WoS: 54Citation - Scopus: 61Synthesis, Cytotoxic and Antimicrobial Activities of Novel Cobalt and ZINC Complexes of Benzimidazole Derivatives(Elsevier Science SA, 2017-01) Apohan, Elif; Yilmaz, Ulku; Yilmaz, Ozgur; Serindag, Ayfer; Kucukbay, Hasan; Yesilada, Ozfer; Baran, YusufIn this study fourteen novel cobalt (II) or zinc (II) complexes of benzimidazoles were synthesized from the 1-(4-substitutedbenzyl)-1H-benzimidazoles and CoCl2.6H(2)O or ZnCl2. Cytotoxic activities of novel complexes were investigated against lung cancer cells (A549) and BEAS-2B. Three of the examined compounds (1, 4 and 5) showed high cytotoxic activity against A549. While the IC50 of the cisplatin was 2.56 pg/mL for A549 cells at 72 h, the IC50 values of compounds 1, 4 and 5 were 1.97, 1.87 and 1.9 mu g/mL, respectively. IC50 values of these compounds for BEAS-2B cells were higher than the IC50 values for A549. While the IC50 values for BEAS-2B cells were 59.8, 24.5 and 32.67 mu g/mL, respectively, the IC50 of the cisplatin was determined as 2.53 pgimL in the present work. Three of the compounds have also high antimicrobial activity against all the microorganisms used. (C) 2016 Elsevier B.V. All rights reserved.Article Citation - WoS: 3Citation - Scopus: 3Robust Reactivity, Neutron Source, and Precursor Estimators for Nuclear Reactors(Elsevier Science SA, 2013-12) Ablay, GunyazReactivity, precursor concentration, and external neutron source strength determine control, operation and performance of nuclear reactors. These main reactor quantities are not directly measurable and must be calculated or estimated using reactor kinetics. This study presents efficient and robust nonlinear estimation algorithms for predicting these fundamental reactor quantities. The effectiveness of the proposed estimators is assessed through chirp and step test signals in the presence of parameter uncertainties and measurement noise. (C) 2013 Elsevier B.V. All rights reserved.