WoS İndeksli Yayınlar Koleksiyonu
Permanent URI for this collectionhttps://hdl.handle.net/20.500.12573/394
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Article Borax-Doped Fe2O3 and CeO2 Nanoparticles Regulate Dose-Dependently Inflammation, the Cell Cycle, and Migration in LPS-Activated THP-1 Cells(Wiley-VCH Verlag GmbH, 2026-03) Sulak, Mine; Ceylan Ekiz, Yağmur; Şen, Alaattin; Acar, Büşra; Çelik Turgut, Gurbet; Aktaş Pepe, NihanThis study examined the biological effects of borax-doped Fe2O3 and CeO2 nanoparticles (NPs) on lipopolysaccharide (LPS)-activated THP-1 cells. The morphology and composition of the nanocomposites were confirmed via scanning electron microscopy (SEM) and energy-dispersive x-ray spectroscopy (EDX). Cell viability (resazurin and crystal violet assays), apoptosis/necrosis (annexin V/propidium iodide [PI]), cell cycle (flow cytometry), migration (scratch assay), and inflammatory response (Iba1 immunofluorescence staining, inducible nitric oxide synthase [iNOS] activity, and RT-PCR) were evaluated. The particle sizes ranged from 21.34 to 33.47 nm (Fe2O3-B-NPs) and 31.07 to 36.62 nm (CeO2-B-NPs). The IC10 and IC50 dose ranges were defined for each nanocomposite and applied across different cell lines to evaluate dose-dependent biological effects. Fe2O3-B-NPs altered cell cycle progression, increasing the number of S phase cells. Both nanocomposites promoted migration at low doses but inhibited it at high doses. CeO2-B-NPs reduced Iba1 levels, whereas Fe2O3-B-NPs increased inflammatory marker levels at higher concentrations. CeO2-B-NPs suppressed TNF-alpha and IL-1 beta gene expression at the IC50 dose, while both nanocomposites reduced iNOS activity. These results indicate that the dose-dependent effects of nanocomposites should be carefully evaluated.Article Citation - WoS: 14Citation - Scopus: 18Fabrication and Electrochemical Behavior Study of Nano-Fibrous Sodium Titanate Composite(Elsevier Science Bv, 2017-02) Ge, Yeqian; Zhu, Jiadeng; Dirican, Mahmut; Jia, Hao; Yanilmaz, Meltem; Lu, Yao; Zhang, XiangwuNanofiber structured Na2Ti3O7 was synthesized via electrospinning process which was further used as an anode material for sodium-ion batteries for the first time. One-dimensional construction of Na2Ti3O7 composite could contribute to better electrochemical activity. It was demonstrated that the capacity of Na2Ti3O7 nanofibers was significantly improved to 257.8 mAh g(-1) at 30 mA g(-1). Furthermore, the rate capability of Na2Ti3O7 nanofibers was significantly enhanced, showing charge capacities were 161.8, 116.5, and 72.4 mAh g(-1) at 100, 200, and 400 mA g(-1), respectively. Therefore, improved specific capacity and rate capability made Na2Ti3O7 nanofibers composite as a promising anode material for sodium-ion batteries.