WoS İndeksli Yayınlar Koleksiyonu
Permanent URI for this collectionhttps://hdl.handle.net/20.500.12573/394
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Article Citation - WoS: 3Citation - Scopus: 3Pericardial Fluid and Vascular Tissue Engineering: A Preliminary Study(Ios Press, 2021-03-23) Sonmezer, Dilek; Latifoglu, Fatma; Toprak, Guler; Duzler, Ayhan; Isoglu, Ismail AlperBACKGROUND: The heart is surrounded by a membrane called pericardium or pericardial cavity. OBJECTIVE: In this study, we investigated the pericardial fluid (PF) for coating polycaprolactone (PCL) scaffolds. PFS, which is a PF component, was used for the coating material. In addition to using PFS for surface coating, MED and fetal bovine serum (FBS) were also used for comparison. METHODS: Pericardial fluid cells (PFSc) isolated from PF were cultured on coated PCL scaffolds for 1, 3, and 5 days. Cell viability was determined using 3-(4, 5-di-methylthiazol- 2-yl)-2, 5-diphenyltetrazolium bromide (MTT) assay. RESULTS: The MTT assay results showed that the viability of cells on PCL scaffold coated with PFS increased over time (P < 0.005), and cell viability was significantly different between PCL scaffolds coated with PFS and non-coated PCL scaffolds. However, cell viability was significantly higher in the PCL scaffolds coated with PFS than non-coated and coated with FBS, MED, and PCL scaffolds. Scanning electron microscopy (SEM) microscopy images and MTT assay indicated that PFSc are attached, proliferated, and spread on PCL scaffolds, especially on PCL scaffolds coated with PFS. CONCLUSIONS: These results suggest that PFS is a biocompatible material for surface modification of PCL scaffolds, which can be used as a suitable material for tissue engineering applications.Article Citation - WoS: 14Citation - Scopus: 13Iterative Image Reconstruction Using Non-Local Means With Total Variation From Insufficient Projection Data(Ios Press, 2016-02-01) Ertas, Metin; Yildirim, Isa; Kamasak, Mustafa; Akan, AydinIn this work, algebraic reconstruction technique (ART) is extended by using non-local means (NLM) and total variation (TV) for reduction of artifacts that are due to insufficient projection data. TV and NLM algorithms use different image models and their application in tandem becomes a powerful denoising method that reduces erroneous variations in the image while preserving edges and details. Simulations were performed on a widely used 2D Shepp-Logan phantom to demonstrate performance of the introduced method (ART + TV) NLM and compare it to TV based ART (ART + TV) and ART. The results indicate that (ART + TV) NLM achieves better reconstructions compared to (ART + TV) and ART.