WoS İndeksli Yayınlar Koleksiyonu
Permanent URI for this collectionhttps://hdl.handle.net/20.500.12573/394
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Conference Object Detection of Variation Instances on Colonoscopy Videos using Structural Similarity Index(IEEE, 345 E 47TH ST, NEW YORK, NY 10017 USA, 2018) Kacmaz, Rukiye Nur; Yilmaz, BulentThe aim of this study is to reduce the number of images extracted from the videos recorded by the specialists during the colonoscopy process for further examination, thereby enabling the specialist to deal with fewer images. Since the images obtained from the videos are very similar, the main assumption of this study is that the whole video can be represented by fewer images. The approach used in this study is the structural similarity index. Totally, images were obtained from 4 different videos coming from healthy, ulcerative colitis, Crohn's, and polyp patients. The noisy images in these videos were eliminated manually. When the structural similarity index between two consecutive clear images was less than 0.83, the second image was selected and shown to the specialist for his/her examination. By this way, the frames carrying significantly new information from the videos were defined as the variation instances. The tests on healthy or diseased colon videos showed that only 5-10% of the clear images provide significantly new information.Conference Object Citation - WoS: 1Citation - Scopus: 1Polyp Localization in Colonoscopy Images Using Vessel Density(Institute of Electrical and Electronics Engineers Inc., 2018-11) Doǧan, Refika Sultan; Yilmaz, BulentIn this paper, we present a new approach for polyp localization in colonoscopy images. This approach is based on the determination of the polyp location using the vessel density in colon images. Primarily, we used pre-processing procedures on the colon images, and then blood vessel extraction techniques were employed. Later, segmentation of the vessel boundaries was performed. With the help of vessel boundaries we calculated the vessel density, and used this for the localization of the polyps. We tested the success of this approach using a publicly available image set (CVC-ClinicDB database). This database consisted of 612 images from 29 different polyps. This approach succeeds in correct detection of 24 out of 29 different polyps. © 2019 Elsevier B.V., All rights reserved.Article Citation - WoS: 14Citation - Scopus: 15Image-Analysis Based Readout Method for Biochip: Automated Quantification of Immunomagnetic Beads, Micropads and Patient Leukemia Cell(Pergamon-Elsevier Science Ltd, 2020-06) Uslu, Fatma; Icoz, Kutay; Tasdemir, Kasim; Dogan, Refika S.; Yilmaz, BulentFor diagnosing and monitoring the progress of cancer, detection and quantification of tumor cells is utmost important. Beside standard bench top instruments, several biochip-based methods have been developed for this purpose. Our biochip design incorporates micron size immunomagnetic beads together with micropad arrays, thus requires automated detection and quantification of not only cells but also the micropads and the immunomagnetic beads. The main purpose of the biochip is to capture target cells having different antigens simultaneously. In this proposed study, a digital image processing-based method to quantify the leukemia cells, immunomagnetic beads and micropads was developed as a readout method for the biochip. Color, size-based object detection and object segmentation methods were implemented to detect structures in the images acquired from the biochip by a bright field optical microscope. It has been shown that manual counting and flow cytometry results are in good agreement with the developed automated counting. Average precision is 85 % and average error rate is 13 % for all images of patient samples, average precision is 99 % and average error rate is 1% for cell culture images. With the optimized micropad size, proposed method can reach up to 95 % precision rate for patient samples with an execution time of 90 s per image.Article Citation - WoS: 7Citation - Scopus: 5Effect of Interpolation on Specular Reflections in Texture-Based Automatic Colonic Polyp Detection(Wiley, 2020-06-26) Kacmaz, Rukiye Nur; Yilmaz, Bulent; Aydin, ZaferReflections of LED light cause unwanted noise effects called specular reflection (SR) on colonoscopic images. The aim of this study was to seek answers to the following two questions. (a) How are the texture features used in automatic detection of polyps affected by the interpolation on specular reflections? (b) If they are affected does it really affect the classification performance? In order to answer these questions, we used 610 colonoscopy images, and divided each image into tiles whose sizes were 32-by-32 pixels. From these tiles, we selected the ones without any specular reflection. We added different shape and size specular reflections cropped from real images onto the reflection-free tiles. We then used the nearest neighbors, bilinear and bicubic interpolation techniques on the tiles on which SRs were added. On these tiles we extracted 116 texture features using 3 second-order approaches, and 4 first-order statistics. First, we used paired samplettest. Second, we performed automatic classification of polyps and background using random forest and k nearest neighbors (k-NN) approaches using the texture features for different combinations of specular reflections added on the tiles from the polyp or background. The results showed that depending on the size of specular reflection, interpolation can cause a significant difference between the texture features that were coming from reflection-free tiles and the same tiles on which interpolation was performed. In addition, we note that bicubic interpolation may be preferred to eliminate specular reflection when texture features are used for background and polyp discrimination.Conference Object Kolonoskopi Görüntülerinde Bilineer İnterpolasyonun Tekstör Analizine Etkisi(Institute of Electrical and Electronics Engineers Inc., 2017-10) Kacmaz, Rukiye Nur; Yilmaz, BulentInterpolation is a method that is used to obtain unknown intensities with the help of known intensities on an image. This method is frequently used in the literature to eliminate light reflection on colonoscopy images. Texture features are the most important characteristics used to describe the region or objects of interest in the image. They are the measures of intensity variation of a surface that determine properties such as smoothness, roughness, and regularity. The aim of this study is to find out the how bilinear interpolation applied on colonoscopy images with reflection impact texture features obtained from the same images. A research carried out to make reasonable comparison between a texture feature from an image with no reflection and the same feature obtained from the same image with synthetically added reflections with various percentages. Using the approaches like gray level co-occurence matrix (GLCM), gray level run length matrix (GLRLM), neighborhood gray tone difference matrix (NGTDM) 126 features were extracted from each 32×32 sub-images coming from 610 colonoscopy images. Several of the features extracted from sub-images with no reflection and reflection were not statistically significantly different, while majority of them were affected from the reflections. © 2018 Elsevier B.V., All rights reserved.Conference Object Citation - Scopus: 1Yapısal Benzerlik İndeksini Kullanarak Kolonoskopi Videolarında Değişim Anlarının Belirlenmesi(IEEE, 2018-11) Kacmaz, Rukiye Nur; Yilmaz, BulentThe aim of this study is to reduce the number of images extracted from the videos recorded by the specialists during the colonoscopy process for further examination, thereby enabling the specialist to deal with fewer images. Since the images obtained from the videos are very similar, the main assumption of this study is that the whole video can be represented by fewer images. The approach used in this study is the structural similarity index. Totally, images were obtained from 4 different videos coming from healthy, ulcerative colitis, Crohn's, and polyp patients. The noisy images in these videos were eliminated manually. When the structural similarity index between two consecutive clear images was less than 0.83, the second image was selected and shown to the specialist for his/her examination. By this way, the frames carrying significantly new information from the videos were defined as the variation instances. The tests on healthy or diseased colon videos showed that only 5-10% of the clear images provide significantly new information.Conference Object Kolonoskopi Görüntülerinden Otomatik Ülseratif Kolit Teşhisi(Institute of Electrical and Electronics Engineers Inc., 2018-11) Kacmaz, Rukiye Nur; Yilmaz, BulentUlcerative colitis (UC) is a disease in which inner surface of colon is inflamed. Ulcers and open scars on the colon are observed. The complaint in the flare period is the frequent bloody diarrhea. Complaints of people with UC increase and decrease periodically. Colonoscopy is the most preferred approach for the visualization of the gastrointestinal tract for the diagnosis and follow-up of related diseases, and UC in particular. The lack of experience of the colonoscopist, complicated locality of the lesion, and the rush in the colonoscopy suite to complete the procedure as soon as possible may cause mistakes in visual analysis. In this study, 200 colonoscopy images (100 normal, 100 UC) were used. The statistical features such as gray level variance, gray level local variance, normalized variance, histogram range, and entropy were extracted from the images, and a normalized 200x5 feature matrix was formed. The normal images and images with UC were discriminated using support vector machines and k-nearest neighbors. It should be noted that the extraction of only 5 features from the colonoscopy images resulted in 95% accuracy. This study demonstrated the feasibility of the development of software tools for aiding the physicians in the diagnosis of colon diseases. © 2019 Elsevier B.V., All rights reserved.