WoS İndeksli Yayınlar Koleksiyonu

Permanent URI for this collectionhttps://hdl.handle.net/20.500.12573/394

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  • Conference Object
    Bioinformatics Analysis of Antifungal Mechanisms in Serratia Fonticola: Protein-Protein Interaction with Botrytis Cinerea BAG1 and Genome-Encoded Enzyme Reportoire
    (Wiley, 2025) Bozkurt, E. B.; Baysal, O.; Marzec-Grzadziel, A.; Silme, R. S.; Can, A.; Belen, I. N.; Korkut, A.
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  • Conference Object
  • Article
    Citation - WoS: 1
    Citation - Scopus: 1
    A Comparative Study of Existing and Current On-Site Documentation of Anatolian Seljuk Kümbets
    (Elsevier Ltd, 2025-12) Güzelci, O.Z.; Türel, A.
    During the Anatolian Seljuk period (1077–1307), monumental tombs known as kümbets emerged as a distinct architectural typology in present-day Türkiye. 2D drawings of these structures, produced since the early 20th century, contain inconsistencies that necessitate verification and accurate documentation. This study digitally documents Anatolian Seljuk kümbets in 3D to generate updated 2D sections reflecting their current condition and compares these with previously published drawings. The methodology includes collecting available 2D sections, digitally documenting kümbets through field studies, generating new 2D sections from 3D models, and systematically comparing these datasets. Two image-based metrics are employed in the comparison: the Exact Pixel Match Ratio (EPMR), which evaluates pixel-level alignment, and the Structural Similarity Index Measure (SSIM), a standard indicator for visual similarity. The results provide a comparative framework for assessing previous drawings and present a verified, up-to-date dataset of kümbet sections for future research. © 2025 Elsevier B.V., All rights reserved.
  • Article
    An Extension of Lucas's Theorem
    (indian Nat Sci Acad, 2025-10-31) Cinkir, Zubeyir; Ozturkalan, Aysegul
    We give elementary proofs of some congruence criteria to compute binomial coefficients modulo a prime number. These criteria are analogues to the symmetry property of binomial coefficients. We give extended version of Lucas's Theorem by using those criteria. We give applications of these criteria by describing a method to derive identities and congruences involving sums of binomial coefficients.
  • Article
    Citation - WoS: 1
    Citation - Scopus: 2
    Green Synthesis and Characterization of Zinc Oxide Nanoparticles via Thyme for Biomedical Applications: Effect of Plant Extract Concentration and Drying Method
    (Springer, 2025-10-15) Karakaya, Humeyra; Kizilates, Burcu; Erdem, Ilker
    Green synthesis of nano particles using plant extracts is sustainable, cost-effective, and eco-friendly. However, the synthesis parameters are still being investigated. In this study, zinc oxide nanoparticles (ZnO NPs) were prepared via thyme extract (green synthesis) and the effect of synthesis parameters were investigated. Samples with different concentrations of thyme plant extract (PE) (10, 16 & 24% (v/v) PE / Zn salt solution) were prepared and two different drying methods (freeze-drying (FD) and oven-drying (OD)) were performed. XRD results showed the hexagonal crystalline ZnO were formed with considerable crystallinity (70.8-75.1%) without further heat treatment (calcination). The crystallite sizes of ZnO NPs were determined to be in the range of 11.9-14.8 nm. The ZnO NPs prepared via PE concentration of 16% (v/v) and freeze-drying was with the finest crystallite size (11.9 nm) and considerable crystallinity (72.9%). ZnO NPs prepared via FD method were found to have smaller particle sizes, thus providing a higher surface-to-volume ratio. DLS (dynamic light scattering) analysis was used for determining the particle size distribution (PSD) and surface charge of ZnO NPs at acidic, neutral and basic pH values. The antibacterial characteristics of ZnO NPs were determined against Gram (+) and (-) bacteria. The ZnO NPs with the finest microstructure (16% PE (v/v), FD) had the highest antibacterial activity. The green synthesized ZnO NPs prepared in this study may be promising candidates for various applications including biomaterials and biomedical applications with their fine microstructure and considerable antibacterial activity.
  • Article
    Sustainable Stabilization of Peat Soil with Hybrid Geopolymer Jet Grout Columns
    (Springer Int Publ A.G., 2025-10-15) Yalcin, Hakan; Erol, Aykut; Kaya, Zulkuf; Cadir, Cenk Cuma; Uncuoglu, Erdal; Akin, Muge K.
    Peat soils present severe challenges in geotechnical engineering due to their low shear strength, high water content, and aggressive chemical environments such as sulfate exposure. While cement-based jet grouting (JG) is widely used, it entails high carbon emissions and energy consumption. Hybrid geopolymer jet grout columns (HGJGCs) are presented in this work as a viable and sustainable alternative. Unlike conventional geopolymer studies that rely on pre-cured molds later exposed to aggressive environments, this research simulates realistic field conditions by injecting fresh geopolymer directly into sulfate-rich peat, where early-age durability and strength are critical. To address early strength limitations commonly seen in aggressive situations, a tiny amount of cement was added to the fly ash/GGBFS-based combination. Crucially, there is no need for high heat because the mechanism cures at room temperature. Physical model testing, laboratory-scale jet grouting, and performance comparisons with conventional JGCs were all carried out. Results show that HGJGCs increased the bearing capacity of peat by 5.5 times, improved compressive strength (5.3-5.7 MPa), and reduced settlement more effectively than JGCs. Additionally, CO2 emissions were reduced by 25.14% due to lower binder-related emissions and energy demand. This work shows that hybrid geopolymer systems are a viable, low-carbon substitute for peat stabilization because they can function well in real-world, chemically demanding situations.
  • Article
    Citation - WoS: 1
    Citation - Scopus: 1
    Interaction of Inula Viscosa (L.) Aiton with IBA1 via Rosmarinic Acid and Rutin: Insights from Computational Models and Biological Effects
    (Wiley-VCH verlag GmbH, 2025-10-29) Aktas Pepe, Nihan; Acar, Busra; Ceylan Ekiz, Yagmur; Senol, Ayse Merve; Semiz, Gurkan; Sen, Alaattin; Celik Turgut, Gurbet
    Inula viscosa (L.) Aiton is a traditional medicinal plant extensively utilized in Mediterranean nations for the treatment of rheumatic pain, inflammatory disorders, diabetes, anemia, and cancer. This study further explored its anti-inflammatory mechanisms through the highest components, chlorogenic acid, rosmarinic acid, and rutin, on the expression of the ionized calcium-binding adapter molecule 1 (Iba1) on monocyte-derived macrophage-like cells. Iba1 is known to contribute pathogenesis of diverse inflammatory diseases. HPLC analysis identified 13 major phenolic compounds, with rosmarinic acid, chlorogenic acid, and rutin as major components. The aqueous extract of the plant and its major components exhibited dose-dependent antiproliferative activity on pTHP-1, RAW264.7, and PCS-201-012 cells. Immunofluorescence staining revealed a significant reduction in Iba1 protein expression, which is associated with inflammation, at the high dose of I. viscosa and rutin. Molecular docking studies indicated that rosmarinic acid and rutin had the strongest predicted interactions with Iba1, with docking scores of -12.403 and -12.301 kcal/mol and MM/GBSA binding energies of -64.47 and -84.20 kcal/mol, respectively. I. visoca and its major components were observed to significantly suppress iNOS activity in LPS-stimulated cells; these findings were also supported by RT-PCR results. Treatment with the high dose of I. viscosa resulted in 9.45% necrotic cells and caused cell cycle arrest in the S phase (59.2 +/- 5.23%). This suggests that it may potentially reduce the proliferation of activated macrophages. In the fibroblast migration assays, the relative wound closure rate was found to be significant 27.06 +/- 18.09% at the low dose of I. viscosa and 31.59 +/- 22.42% at the high dose of I. viscosa. Although the relatively low wound closure rate limits tissue repair, it may benefit chronic wounds and fibrosis by suppressing excessive cell proliferation and inflammation. These results suggest that I. viscosa is a promising natural source of bioactive compounds with potential applications in anti-inflammatory drug development.
  • Article
    Citation - WoS: 1
    Citation - Scopus: 1
    A Comprehensive Review on the Extraction and Recovery of Lithium from Primary and Secondary Sources: Advances Toward Battery-Grade Materials
    (Wiley, 2025-10-20) Top, Soner; Kursunoglu, Sait; Altiner, Mahmut
    Lithium-ion battery (LIB) technologies have become indispensable to modern energy systems, driving global demand for high-purity lithium compounds. This review focuses on lithium recovery and purification strategies for battery-grade lithium carbonate (Li2CO3) and lithium hydroxide (LiOH), addressing both primary sources (brines and minerals) and secondary sources (waste materials). Industrially established processes, such as evaporation-based brine treatment and conventional metallurgical methods, are discussed alongside emerging techniques, including membrane separation, solvent extraction, and CO2-assisted precipitation. Particular attention is given to lithium precipitation mechanisms, the behaviour of co-existing ions during extraction, and the specific quality requirements for cathode material synthesis. By evaluating process scalability, environmental impact, and product purity, this review provides a comprehensive understanding of current practices and future directions. Additionally, it highlights the growing importance of lithium in the context of accelerating electric vehicle (EV) adoption, underscoring the bright and expanding future of the lithium industry.
  • Article
    Enhanced Photoluminescence via Plasmonic Gold Nanoparticles and Improved Stability of Perovskite Nanocrystals in Macroporous (Polydimethylsiloxane) PDMS Matrices
    (Springer, 2025-10-09) Ocal, Sema Karabel; Tiras, Kevser Sahin; Onses, M. Serdar; Mutlugun, Evren
    In this work, we report a simple and cost-effective method for improving both the environmental stability and photoluminescence quantum efficiency (PLQY) of perovskite nanocrystals (PNCs). Through their embedding in a specially designed macroporous polydimethylsiloxane (MPDMS) matrix and incorporation of plasmonic gold nanoparticles (Au NPs), remarkable improvements are achieved. The resulting MPDMS@PNC composites are seen to retain near-unity quantum efficiency even after 24-h immersion in water and are observed to retain over 85% of the original efficiency even at 75 degrees C, displaying excellent thermal stability. More interestingly, by incorporating Au NPs and subjecting the material to mechanical pressure, the lifetime of the PNCs gets further increased. This is due to the more intimate spatial arrangement of Au NPs in the porous matrix, enhancing localized surface plasmon resonance (LSPR) coupling and thereby enhancing the photoluminescence (PL) of the PNCs. In general, this approach offers a scalable and robust route to designing stable, high-performance perovskite-based materials for next-generation optoelectronic applications.