PubMed İndeksli Yayınlar Koleksiyonu
Permanent URI for this collectionhttps://hdl.handle.net/20.500.12573/397
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Article Does Your Love Lift Me Higher? A Direct Replication of the Energising Role of Secure Relationships(John Wiley & Sons Ltd, 2025-12-07) Lagap, Adar Cem; Harma, MehmetPrevious work has revealed that priming people with significant others increases feelings of security and energy, and in turn, boosts exploration motivations. In this preregistered study, we directly replicated Luke et al.'s (2012) Study 2 (N = 281). We found similar results as the replicated study regarding increased security feelings and exploration motivations on the self-report measures after the priming. However, we did not find any support for the increased energy feelings after the attachment security priming. In addition, contrary to Luke et al.'s (2012) results, energy feelings did not mediate the relationship between security priming and exploration motivations. A discussion of null findings, along with the limitations of self-reports and potential misinterpretation of the mediational analyses, follows. We also discuss possible future implications of the current findings.Article Measuring Disaster Resilience in MENA Countries and Its Impact on Disaster Losses(Nature Portfolio, 2025-12-08) Demir, Abdullah; Dincer, Ali Ersin; Dincer, Nazire NergizDisaster resilience is a protective feature aimed at reducing the effects of natural disaster events and losses resulting from these events. This study develops a Disaster Resilience Index (DRI) for MENA countries to assess resilience across ten dimensions, including economic, social, institutional, infrastructural, and environmental factors. Unlike most prior studies, which focus on individual countries or use narrower sets of indicators, this study provides a multi-country, region-specific framework tailored to MENA's socio-economic and environmental heterogeneity. The index integrates geospatial data on disaster risk from geographic information systems (GIS) and a natural hazard risk dimension. Validation using disaster-related fatalities, supported by a dual PCA-based sensitivity analysis, confirms the robustness of the DRI and reveals that countries with stronger governance, higher human capital, and robust infrastructure tend to exhibit greater resilience, while fragile states and resource-dependent economies are more vulnerable. Notably, the DRI calculated using both dimension-specific and all-indicator PCA produces closely aligned values, indicating the choice of conducting PCA at the dimension level does not significantly alter the overall assessment of disaster resilience. These insights provide a foundation for targeted disaster risk reduction strategies and highlight areas where international cooperation and policy interventions can strengthen resilience in the region.Article Vim-Polyp: Multimodal Colon Polyp Dataset with Video, Histopathology, and Protein Expression(Nature Portfolio, 2025-12-03) Dogan, Refika Sultan; Akay, Ebru; Dogan, Serkan; Yilmaz, BulentThe dataset in this study includes 202 videos with a total of 422 minutes, reaching Kayseri City Hospital's gastroenterology department as colonoscopy videos and 1903 microscopy images between 2019 and 2021. It includes 399 colonoscopy, microscopy images, and pathological diagnoses of polyps, as well as immunohistochemical staining results for proteins that play an important role in the assessment of cancerous cells, such as staining results for p53 (clone: bp53-11), Ki-67 (clone: 30-9), CD34 (clone: QBend/10), PD-L1 (clone: SP142), BRAF (clone: V600E) and VEGF (clone: SP125). By sharing the data openly, we aim to facilitate benchmarking, exploratory analysis and transfer-learning studies on colorectal polyps and cancer. In combination with external datasets or pretrained models, the resource can help advance data-driven detection and characterisation work. The diverse range of polyps assigned to cancer stages from 201 patients makes this tool valuable for researchers and clinicians in furthering diagnosis and treatment.Article Development and Characterization of Starch-Fatty Acid Complexes Produced with Buckwheat Starch and Capric/Stearic Acid Using Different Reaction Conditions(Elsevier, 2025-12) Oskaybas-Emlek, Betul; Ozbey, Ayse; Aydemir, Levent Yurdaer; Kahraman, KevserThe aim of present study was to investigate the impact of reaction parameters on the complex formation between buckwheat starch and capric acid (B-Capric) or stearic acid (B-Stearic). The most effective parameters on complex formation indicator (Complex index (CI) value) were found as reaction temperature (60-90 degrees C) and pH (5-8). Additionally, the effect of these parameters on physicochemical, pasting, and in-vitro digestibility properties of complex samples were evaluated. XRD and FTIR was also used in characterize the complex samples. In general, increasing pH increased the CI values of B-Stearic samples while decreasing those of B-Capric samples. Syneresis of buckwheat starch increased after complexation while paste clarity and swelling power diminished. The pasting properties of native starch significantly changed after complex formation. The FTIR results showed that starch structure changed with complex formation. XRD revealed that buckwheat starch, having an A-type pattern, converted to V-type pattern after complexation. Complex formation of buckwheat starch with capric and stearic acid significantly increased the RS content of buckwheat starch (19.01 %) by up to 36.25 % and 30.60 %, respectively. These results highlight the possibility of using buckwheat starch-capric acid/stearic acid complexes in food formulation to enhance the RS content.Article Citation - Scopus: 1Labyrinthine Microstructures With a High Dipole Moment Boron Complex for Molecular Physically Unclonable Functions(American Chemical Society, 2025-10-29) Yıldız, T.A.; Kiremitler, N.B.; Kayacı, N.; Kalay, M.; Özcan, E.; Deneme, I.; Usta, H.The design and development of novel molecular-physically unclonable functions (PUFs) with advanced encoding characteristics and ease of fabrication have recently attracted attention in cryptography, secure authentication, and anticounterfeiting. Here, we report the development of a new high dipole-moment small molecule, InIm-BF<inf>2</inf>, a difluoroborate complex of an indolyl-imine ligand, and the fabrication of unique labyrinthine patterns through a facile two-step thin film process under ambient conditions. The new molecule has a dipolar, coplanar π-backbone and arranges in the solid state with antisymmetric cofacial π-stackings (3.86 Å). These properties, along with short C–H···π contacts (2.74–2.88 Å) and nonclassical C–H···F hydrogen bonds (2.47–2.51 Å) (23.4% and 11.5% of the Hirshfeld surfaces, respectively), drive the formation of amorphous molecular PUF patterns with disordered, short-range interactions. Spin-coating followed by thermal annealing at a moderate temperature produces nanoscopic molecular thin films with intricate labyrinthine patterns. These patterns, characterized by interconnected, irregularly shaped, micron-sized (≈50–100 μm) features, exhibit excellent PUF characteristics, verified through advanced image analysis and computational algorithms. Unlike randomly positioned isolated features in classical binarized keys, the interconnected labyrinthine patterns possess rich entropy and complex features, directly authenticated via deep-learning methodologies. Our work not only demonstrates a facile, promising approach to fabricating unique high-entropy PUF patterns but also provides critical insights into designing advanced molecular materials for next-generation security applications. © 2025 The Authors. Published by American Chemical SocietyArticle The Clinical Efficacy of Psychological Interventions for Bipolar Depression: A Systematic Review and Individual Patient Data (IPD) Meta-Analysis(Cambridge University Press, 2025) Yilmaz, Sakir; Huguet, Anna; Kisely, Steve; Rao, Sanjay; Wang, Jianli; Price, Molly; Wright, KimUnlike conventional meta-analyses, individual patient data (IPD) meta-analysis assesses moderator variables at the level of each participant, which generates more precise and biased estimates. The objective of this study was to investigate whether psychological therapy reduces depression symptoms in people with Bipolar I and II disorders and examine whether baseline depression has a moderating effect on treatment outcomes. Through the use of several electronic databases, a systematic search was conducted. Eligible studies were randomized controlled trials evaluating a psychological intervention for adults diagnosed with Bipolar I or II disorder. Titles and abstracts were screened, followed by full texts. The authors of the included studies were asked to provide IPD from their trials. A multilevel model approach was used to analyze the data. From the 7552 studies found by our searches, six studies with 668 study participants were eligible. Intervention significantly reduced depression scores. There was a significant association between baseline depression and post treatment depression scores. There was no statistically significant interaction between condition allocation and baseline depression score. When IPD from the two most comparable studies were analyzed, CBT had reduced depression scores relative to the comparator condition. The study included patient data from only six studies which were heterogeneous in terms of intervention type, outcome measure, and comparators. Overall, the psychological interventions tested significantly reduced bipolar depression scores. There was no evidence of moderation by baseline depression scores.
