PubMed İndeksli Yayınlar Koleksiyonu
Permanent URI for this collectionhttps://hdl.handle.net/20.500.12573/397
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Correction Citation - WoS: 2Citation - Scopus: 2The Influence of Cement Kiln Dust on Strength and Durability Properties of Cement-Based Systems(Springer Heidelberg, 2022-06-15) Hakkomaz, Hadiye; Yorulmaz, Hediye; Durak, Ugur; Ilkentapar, Serhan; Karahan, Okan; Atis, Cengiz DuranArticle Citation - WoS: 7Citation - Scopus: 7The Influence of Cement Kiln Dust on Strength and Durability Properties of Cement-Based Systems(Springer Heidelberg, 2022-06-06) Hakkomaz, Hadiye; Yorulmaz, Hediye; Durak, Ugur; Ilkentapar, Serhan; Karahan, Okan; Atis, Cengiz DuranThere are very few studies in the literature on the usage of CKD in cementitious systems. This article presents the laboratory study results on the influence of cement kiln dust (CKD) on the properties of mortar made with cement kiln dust and Portland cement. The article aims to prevent CKD's (known as a hazardous waste product) damage to nature by utilizing CKD in cementitious systems and contributing to sustainability by reducing cement amount in the cementitious system. For this purpose, 5%, 10%, 15%, and 20% of CKD were replaced with cement and binary cementitious systems were formed. For all mortar mixes, the water/binder ratio was kept constant at 0.5, and the sand/binder ratio was 3. Workability, dry unit weight, water absorption ratio and porosity, flexural strength, compressive strength, abrasion, carbonation, and high-temperature resistance tests were performed on the mortar specimens. Based on the results of laboratory work, it was observed that the replacement of CKD with cement reduces the workability of fresh mortar. Compressive and flexural strengths of CKD-added mixtures were found to be equivalent or insignificantly lower than that of the control sample. The addition of CKD had a negligible effect on water absorption and porosity of samples. Besides, the residual compressive strength determined after the elevated temperature test for the sample made with CKD were found to be equivalent or higher compared to the control sample. Present laboratory studies showed that utilization of CKD in cementitious mortar system is feasible in terms of testing conducted.Article Citation - WoS: 111Citation - Scopus: 136The Impacts of Organizational Green Culture and Corporate Social Responsibility on Employees' Responsible Behaviour Towards the Society(Springer Heidelberg, 2022-04-12) Abbas, Jawad; Dogan, EyupCorporate social responsibility (CSR) initiatives and organizational green culture (OGC) play a significant role in developing organizations and society. However, the extent to which these activities encourage organizational employees to act socially responsible outside their workplace is yet to be explored. This study uses the Operant conditioning theory to examine the effect of OGC and CSR activities on employees' responsible behaviour towards the society (ERBS) outside their organizations. To collect data, we focused on employees of public and private manufacturing and services firms and analysed it using the structural equation modelling (SEM) technique). It is found that OGC and CSR activities significantly reshape employees' behaviour, and they tend to behave in a socially responsible manner in society. Moreover, the relationship between OGC and ERBS' is partially mediated by CSR. It is also found that female workers tend to behave more socially responsibly than male workers. This study suggests that firms should adopt a green culture and CSR practices since it promotes socially responsible behaviour (a better citizen) among their employee, which is essential for a sustainable society.Article Citation - WoS: 21Citation - Scopus: 25The Impact of Organic Cotton Use and Consumer Habits in the Sustainability of Jean Production Using the LCA Approach(Springer Heidelberg, 2022-09-14) Fidan, Fatma Sener; Aydogan, Emel Kizilkaya; Uzal, Nigmet; Şener Fidan, Fatma; Kızılkaya Aydoğan, EmelDue to the rise in clothing consumption per person and growing consumer awareness of environmental issues with products, the textile industry must adopt new practices for improving sustainability. The current study thoroughly investigates the benefits of using organic cotton fiber instead of conventional cotton fiber. Because of the extensive use of natural resources in the production of cotton, the primary raw material for textiles, which accounts for the environmental effects of a pair of jeans, a life cycle assessment methodology was used to examine these effects in four different scenarios. The additional scenarios were chosen based on the user preferences for washing temperatures, drying methods, and the type of cotton fiber used in the product. The environmental impact categories of global warming potential, eutrophication potential terrestrial ecotoxicity potential, acidification potential, and freshwater ecotoxicity potential were analyzed by the CML-IA method. The life cycle assessment results revealed that the lowest environmental impacts were obtained for scenario 4 with 100% organic cotton fiber with an improvement of 87% in terrestrial ecotoxicity potential and 59% in freshwater ecotoxicity potential. All of the selected environmental impacts of a pair of jeans are reduced in all scenarios when organic cotton is used. Additionally, consumer habits had a significant impact on all impact categories. Using a drying machine instead of a line dryer during the use phase is just as important as the washing temperature. The environmental impact hotspots for a pair of jeans were revealed to be the eutrophication potential, acidification potential, and global warming potential categories during the use phase, and the terrestrial ecotoxicity potential and freshwater ecotoxicity potential categories during the fabric manufacturing including cotton cultivation. The use of organic cotton as a raw material in manufacturing processes, as well as consumer preferences for washing temperature and drying methods, appears to have significant environmental impacts on a pair of jeans' further sustainable life cycle.Article Citation - WoS: 450Citation - Scopus: 485The Impact of Economic Structure to the Environmental Kuznets Curve (EKC) Hypothesis: Evidence from European Countries(Springer Heidelberg, 2020-02-01) Dogan, Eyup; Inglesi-Lotz, RoulaThe purpose of this study is to examine the role of economic structure of European countries into testing the Environmental Kuznets Curve (EKC) hypothesis for European countries for the period 1980 to 2014. This study is inspired by the work of Lin et al. (J Clean Prod 133:712-724, 2016), which made the first effort to investigate the phenomenon looking only at African countries. The main finding of the study is that the overall economic growth is the factor with which CO2 emissions exhibit an inverted U-shaped relationship in the studied country group. On the contrary, when using their industrial share as a proxy to capture the countries' economic structure, the EKC hypothesis is not confirmed - but a U-shaped relationship is confirmed. The industrial share decreases emissions through the development and absorption of technologies that are energy efficient and environmental friendly. The EKC hypothesis is confirmed when the aggregate GDP growth is considered, taking into account the improvement of the overall economic conditions of the countries regardless of the economic structure and role of industrialization.Article Citation - WoS: 17Citation - Scopus: 17Removal of Pesticides From Secondary Treated Urban Wastewater by Reverse Osmosis(Springer Heidelberg, 2022-04-11) Ates, Nuray; Uzal, Nigmet; Yetis, Ulku; Dilek, Filiz B.The residues of pesticides that reach water resources from agricultural activities in several ways contaminate drinking water resources and threaten aquatic life. This study aimed to investigate the performance of three reverse osmosis (RO) membranes (BW30-LE, SW30-XLE, and GE-AD) in rejecting four different pesticides (tributyl phosphate, flutriafol, dicofol, and irgarol) from secondary treated urban wastewater and also to elucidate the mechanisms underlying the rejection of these pesticides. RO experiments were conducted using pesticide-spiked wastewater samples under 10 and 20 bar transmembrane pressures (TMP) and membrane performances were evaluated. Overall, all the membranes tested exhibited over 95% rejection performances for all pesticides at both TMPs. The highest rejections for tributyl phosphate (99.0%) and irgarol (98.3%) were obtained with the BW30-LE membrane, while for flutriafol (99.9%) and dicofol (99.1%) with the GE-AD membrane. The increase in TMP from 10 to 20 bar did not significantly affect the rejections of all pesticides. The rejection performances of RO membranes were found to be governed by projection area as well as molecular weight and hydrophobicity/hydrophilicity of pesticides. Among the membranes tested, the SW30-XLE membrane was the most prone to fouling due to the higher roughness.Article Citation - Scopus: 25Recursive Cluster Elimination Based Rank Function (SVM-RCE-R) Implemented in KNIME(F1000 Research Ltd, 2021-01-05) Yousef, Malik; Bakir-Güngör, Burcu; Jabeer, Amhar; Göy, Gökhan; Qureshi, Rehman A.; C Showe, Louise; C. Showe, LouiseIn our earlier study, we proposed a novel feature selection approach, Recursive Cluster Elimination with Support Vector Machines (SVM-RCE) and implemented this approach in Matlab. Interest in this approach has grown over time and several researchers have incorporated SVM-RCE into their studies, resulting in a substantial number of scientific publications. This increased interest encouraged us to reconsider how feature selection, particularly in biological datasets, can benefit from considering the relationships of those genes in the selection process, this led to our development of SVM-RCE-R. SVM-RCE-R, further enhances the capabilities of SVM-RCE by the addition of a novel user specified ranking function. This ranking function enables the user to stipulate the weights of the accuracy, sensitivity, specificity, f-measure, area under the curve and the precision in the ranking function This flexibility allows the user to select for greater sensitivity or greater specificity as needed for a specific project. The usefulness of SVM-RCE-R is further supported by development of the maTE tool which uses a similar approach to identify MicroRNA (miRNA) targets. We have also now implemented the SVM-RCE-R algorithm in Knime in order to make it easier to applyThe use of SVM-RCE-R in Knime is simple and intuitive and allows researchers to immediately begin their analysis without having to consult an information technology specialist. The input for the Knime implemented tool is an EXCEL file (or text or CSV) with a simple structure and the output is also an EXCEL file. The Knime version also incorporates new features not available in SVM-RCE. The results show that the inclusion of the ranking function has a significant impact on the performance of SVM-RCE-R. Some of the clusters that achieve high scores for a specified ranking can also have high scores in other metrics. © 2021 Elsevier B.V., All rights reserved.Article Citation - WoS: 73Citation - Scopus: 81Prophylactic and Therapeutic Roles of Oleanolic Acid and Its Derivatives in Several Diseases(Baishideng Publishing Group inc, 2020-05-26) Sen, AlaattinOleanolic acid (OA) and its derivatives are widely found in diverse plants and are naturally effective pentacyclic triterpenoid compounds with broad prophylactic and therapeutic roles in various diseases such as ulcerative colitis, multiple sclerosis, metabolic disorders, diabetes, hepatitis and different cancers. This review assembles and presents the latestin vivoreports on the impacts of OA and OA derivatives from various plant sources and the biological mechanisms of OA activities. Thus, this review presents sufficient data proposing that OA and its derivatives are potential alternative and complementary therapies for the treatment and management of several diseases.Article Citation - WoS: 54Citation - Scopus: 66Optical Detection of Microplastics in Water(Springer Heidelberg, 2021-01-19) Iri, Ahmet H.; Shahrah, Malek H. A.; Ali, Ali M.; Qadri, Sayed A.; Erdem, Talha; Ozdur, Ibrahim T.; Icoz, KutayUnfortunately, the plastic pollution increases at an exponential rate and drastically endangers the marine ecosystem. According to World Health Organization (WHO), microplastics in drinking water have become a concern and may be a risk to human health. One of the major efforts to fight against this problem is developing easy-to-use, low-cost, portable microplastic detection systems. To address this issue, here, we present our prototype device based on an optical system that can help detect the microplastics in water. This system that costs less than $370 is essentially a low-cost Raman spectrometer. It includes a collimated laser (5 mW), a sample holder, a notch filter, a diffraction grating, and a CCD sensor all integrated in a 3D printed case. Our experiments show that our system is capable of detecting microplastics in water having a concentration less than 0.015% w/v. We believe that the designed portable device can find a widespread use all over the world to monitor the microplastic content in an easier and cost-effective manner.Article Citation - WoS: 17Citation - Scopus: 18Obesity Induced by High-Fat Diet Is Associated With Critical Changes in Biological and Molecular Functions of Mesenchymal Stromal Cells Present in Visceral Adipose Tissue(Impact Journals LLC, 2020-12-27) Acar, Mustafa Burak; Ayaz-Guner, Serife; Di Bernardo, Giovanni D.; Guner, Hüseyin; Murat, Ayşegül; Peluso, G. F.; Galderisi, UmbertoThe mesenchymal stromal cells (MSCs) residing within the stromal component of visceral adipose tissue appear to be greatly affected by obesity, with impairment of their functions and presence of senescence. To gain further insight into these phenomena, we analyzed the changes in total proteome content and secretome of mouse MSCs after a high-fat diet (HFD) treatment compared to a normal diet (ND). In healthy conditions, MSCs are endowed with functions mainly devoted to vesicle trafficking. These cells have an immunoregulatory role, affecting leukocyte activation and migration, acute inflammation phase response, chemokine signaling, and platelet activities. They also present a robust response to stress. We identified four signaling pathways (TGF-β, VEGFR2, HMGB1, and Leptin) that appear to govern the cells’ functions. In the obese mice, MSCs showed a change in their functions. The immunoregulation shifted toward pro-inflammatory tasks with the activation of interleukin-1 pathway and of Granzyme A signaling. Moreover, the methionine degradation pathway and the processing of capped intronless pre-mRNAs may be related to the inflammation process. The signaling pathways we identified in ND MSCs were replaced by MET, WNT, and FGFR2 signal transduction, which may play a role in promoting inflammation, cancer, and aging © 2024 Elsevier B.V., All rights reserved.