Browsing by Author "Ildiz, Nilay"

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Citation - WoS: 5
Citation - Scopus: 7
Rational Design of EDTA-Incorporated Nanoflowers as Novel and Effective Endodontic Disinfection Against Biofilms
(Springer, 2024) Aslan, Tugrul; Dadi, Seyma; Kafdag, Ozgur; Temur, Nimet; Ildiz, Nilay; Ocsoy, Ismail; Ustun, Yakup
The ethylenediaminetetradiacetic acid (EDTA) is one of the most commonly used irrigation solutions. Although EDTA has a very low antimicrobial property, it is used to remove inorganic part of smear layer in areas of root canal system. Herein, we developed EDTA-incorporated nanoflowers (EDTA NFs), for the first time, as novel and effective irrigation solution with quite high antimicrobial property to provide complete disinfection in root canal system. We both systematically elucidated the formation of the EDTA NFs with various techniques, and their catalytic and antimicrobial activities in the presence of hydrogen peroxide (H2O2) were documented through intrinsic EDTA property and peroxidase-like activities.
Citation - WoS: 15
Citation - Scopus: 16
Natural Molecule-Incorporated Magnetic Organic-Inorganic Nanoflower: Investigation of Its Dual Fenton Reaction-Dependent Enzyme-Like Catalytic Activities With Cyclic Use
(Wiley-VCH Verlag GmbH, 2023) Dadi, Seyma; Cardoso, Marlon Henrique; Mandal, Amit Kumar; Franco, Octavio Luiz; Ildiz, Nilay; Ocsoy, Ismail
The functional organic-inorganic hybrid nanoflowers (hNFs) have recently attracted considerable attention due to enhanced catalytic activity and stability. The main purpose of this study is to synthesize new Fenton reagents and investigate their catalytic activity, dye degradation performance and antimicrobial activity. This magnetic gallic acid nanoflowers (FeGANF) were self-assembled via incorporating magnetic nanoparticles (Fe3O4 NPs) into gallic acid (GA) as organic part and copper(II) phosphate (Cu-3(PO4)(2)) as inorganic parts. The FeGANF were characterized by SEM, EDX, FT-IR and XRD. The peroxidase-like activity and dye degradation performance of FeGANF and GANF based on Fenton reaction in the presence of H2O2 was studied toward guaiacol as substrate, using methylene blue (MB) and congo red (CR) as a cationic and anionic dyes, respectively. FeGANF shows much high catalytic activity and decoloration efficiency (97 % for MB and 99 % for CR) because of dual active center in Fenton reaction on the surface of FeGANF. FeGANF exhibited more antimicrobial activity against Escherichia coli ATCC 25922, Staphylococcus aureus ATCC 25923, and Candida albicans ATCC 10231 than that of the GA and GANF. The results of these studies suggest that magnetic hNFs has proved to be promising Fenton reagents for biological and environmental applications including treatment of wastewater.