Browsing by Author "Boyuk, Mustafa"

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Design, modeling, and control of a horizontal magnetic micromanipulator
(SAGE PUBLICATIONS LTD, 1 OLIVERS YARD, 55 CITY ROAD, LONDON EC1Y 1SP, ENGLAND, 2019) Ablay, Gunyaz; Boyuk, Mustafa; Icoz, Kutay; 0000-0002-0947-6166; 0000-0003-2862-6761; AGÜ, Mühendislik Fakültesi, Elektrik - Elektronik Mühendisliği Bölümü
Magnetic micromanipulators with a wide range of force generating capabilities are able to manipulate micron size particles for various applications and measurements. These magnetic particles can be coated with receptors to specifically bind to target biomolecules. In this work, a horizontal magnetic micromanipulator is designed, modeled and controlled for single micron size magnetic particle manipulations. A method is presented for dynamic modeling of magnetic micromanipulators. A feedback control method is designed that allows direct linearization of the system. It is shown that the proposed controller guarantees the stability of the closed-loop system, and yields zero steady-state error in a wide range of operation conditions. We show that the micromanipulator is able to generate a wide range of piconewton (pN) scale forces on a superparamagnetic particle for single molecule separation, and biosensor developments.
Feedback controller designs for an electromagnetic micromanipulator
(SAGE PUBLICATIONS LTD, 1 OLIVERS YARD, 55 CITY ROAD, LONDON EC1Y 1SP, ENGLAND, 2019) Boyuk, Mustafa; Eroglu, Yakup; Ablay, Gunyaz; Icoz, Kutay; 0000-0002-0947-6166; 0000-0003-2862-6761; AGÜ, Mühendislik Fakültesi, Elektrik - Elektronik Mühendisliği Bölümü
Magnetic micromanipulators are capable of generating wide range of magnetic forces to manipulate magnetic microparticles for biomedical applications. In this study, a multipole magnetic micromanipulator system including electromagnets, driver circuitry and control unit is designed, modeled and implemented. The micromanipulator can produce a broad range of magnetic forces up to 25 pN on a single magnetic microparticle (1-10 mu m diameter) that is 5 mm away from the electromagnet core tip. Both linear and nonlinear controllers are designed and implemented, and the proposed nonlinear controller produces smooth control currents to assure closed-loop stability of the system with 1 s non-overshoot transient response and zero steady-state tracking error. The maximum output current of the driver circuitry is set to 1 A. The single particle at the center is moved at a speed of 5 mm/s. The fully automatic system can be utilized in applications related to single cell or microparticle manipulations.
A horizontal magnetic tweezer for single molecule micromanipulations
(IEEE, 345 E 47TH ST, NEW YORK, NY 10017 USA, 2018) Ablay, Gunyaz; Boyuk, Mustafa; Eroglu, Yakup; Icoz, Kutay; 0000-0002-0947-6166; AGÜ, Mühendislik Fakültesi, Elektrik - Elektronik Mühendisliği Bölümü
Magnetic tweezers are able to manipulate cells or biomolecules for various applications and measurements. In this work, a horizontal magnetic tweezer is designed, modeled and controlled for single molecule manipulations. A method is presented for dynamic modeling of horizontal magnetic tweezers. A linear control method is designed to ensure a wide range of operation conditions with zero steady-state error. The horizontal magnetic tweezer is able to generate a wide range of piconewton scale forces on a superparamagnetic microparticle for single molecule separation, and biosensor developments.