Yaşam ve Doğa Bilimleri Fakültesi
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Conference Object Ceramide is a key factor that regulates the crosstalk between TGF-beta and sonic hedgehog signaling at the basal cilia to control cell migration and tumor metastasis(ELSEVIER SCI LTDTHE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND, 2016) Gencer, Salih; Ogretmen, Besim; AGÜ, Yaşam ve Doğa Bilimleri Fakültesi, Moleküler Biyoloji ve Genetik Bölümü; Gencer, Salih; 01. Abdullah Gül UniversityCeramide is a key factor that regulates the crosstalk between TGF-beta and sonic hedgehog signaling at the basal cilia to control cell migration and tumor metastasisConference Object Ceramide Is a Key Factor That Regulates the Crosstalk Between TGF-Β and Sonic Hedgehog Signaling at the Basal Cilia to Control Cell Migration and Tumor Metastasis(Federation Amer Soc Exp Biol, 2016) Gencer, Salih; Oleinik, Natalia; Dany, Mohammed; Ogretmen, Besim; 01. Abdullah Gül UniversityConference Object Ceramide Is a Key Factor That Regulates the Crosstalk Between TGF-Β and Sonic Hedgehog Signaling at the Basal Cilia to Control Cell Migration and Tumor Metastasis(Elsevier Sci Ltd, 2016) Gencer, S.; Ogretmen, B.; AGÜ, Yaşam ve Doğa Bilimleri Fakültesi, Moleküler Biyoloji ve Genetik Bölümü; Gencer, Salih; 01. Abdullah Gül UniversityConference Object Computer-Aided Classification of Breast Cancer Histopathological Images(IEEE345 E 47TH ST, NEW YORK, NY 10017 USA, 2017) Aksebzeci, Bekir Hakan; Kayaalti, Omer; AGÜ, Yaşam ve Doğa Bilimleri Fakültesi, Biyomühendislik Bölümü; 01. Abdullah Gül UniversityNowadays, one of the most common types of cancer is breast cancer. The early and accurate diagnosis of breast cancer has great importance in the treatment of the disease. In the diagnosis of breast cancer, histopathological analysis of cell and tissue specimens taken by biopsy is considered as the gold standard. Histopathological analysis is a tedious process that is highly dependent on the knowledge and experience of the pathologists. In this study; it is aimed to develop a computer-aided system that can reduce the workload of pathologists and help them in their diagnosis. An image set containing benign and malignant tumor images of breast cancer has been studied. To perform texture analysis on tumor images; first order statistics, Gabor and gray-level co-occurrence matrix (GLCM) feature extraction methods have been applied. Then, various classifiers were applied to the obtained feature matrices and their performances were compared. The highest classification accuracy was achieved 82.06% by Random Forests classifier with feature combination of Gabor and GLCM methods. The results presented here show that computer-assisted diagnosis of breast cancer is a promising field.Conference Object Investigation of the Antitumor Effect of Targeting PI3K-AKT-mTOR Pathway and Histone Deacetylase Enzymes on Acute Myeloid Leukemia Cells(Cig Media Group, Lp, 2021) Sansacar, Merve; Sagir, Helin; Akcok, Emel Gencer; AGÜ, Yaşam ve Doğa Bilimleri Fakültesi, Biyomühendislik Bölümü; Sansacar, Merve; Sagir, Helin; Akcok, Emel Gencer; 01. Abdullah Gül University; 04. Yaşam ve Doğa Bilimleri Fakültesi; 04.01. Biyomühendislik; 04.02. Moleküler Biyoloji ve GenetikConference Object A novel signaling pathway that governs tumor metastasis: ceramide regulates direct crosstalk between TGF-beta and sonic hedgehog signaling(WILEY111 RIVER ST, HOBOKEN 07030-5774, NJ, 2016) Gencer, Salih; Ogretmen, B.; AGÜ, Yaşam ve Doğa Bilimleri Fakültesi, Moleküler Biyoloji ve Genetik Bölümü; 01. Abdullah Gül UniversityA novel signaling pathway that governs tumor metastasis: ceramide regulates direct crosstalk between TGF-beta and sonic hedgehog signalingConference Object A Novel Signaling Pathway That Governs Tumor Metastasis: Ceramide Regulates Direct Crosstalk Between TGF-Β and Sonic Hedgehog Signaling(Federation Amer Soc Exp Biol, 2016) Gencer, Salih; Ogretmen, Besim; AGÜ, Yaşam ve Doğa Bilimleri Fakültesi, Moleküler Biyoloji ve Genetik Bölümü; Gencer, Salih; 01. Abdullah Gül UniversityConference Object Poly(OEGMA)-B Block Copolymer Nanocarriers for Anticancer Agent Release(Wiley, 01.06.2018) Aksit, N. N.; Topuzogullari, M.; Isoglu, I. A.; El Khatib, M.; Isoglu, S. Dincer; 0000-0002-8697-1654; AGÜ, Yaşam ve Doğa Bilimleri Fakültesi, Moleküler Biyoloji ve Genetik Bölümü; 01. Abdullah Gül University; 04. Yaşam ve Doğa Bilimleri Fakültesi; 04.01. BiyomühendislikConference Object TGF-Β Receptor I/II Signaling at Primary Cilia Membrane Is Regulated by Ceramide to Modulate Cell Migration(Elsevier Sci Ltd, 2016) Gencer, S.; Ogretmen, B.; AGÜ, Yaşam ve Doğa Bilimleri Fakültesi, Moleküler Biyoloji ve Genetik Bölümü; Gencer, Salih; 01. Abdullah Gül University
